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Results for "

fibroblast-activation protein

" in MedChemExpress (MCE) Product Catalog:

By Targets:	FAP (52) ADC Payload (2) Biochemical Assay Reagents (1) Dipeptidyl Peptidase (2) Drug Derivative (1) Drug Intermediate (4) Drug-Linker Conjugates for ADC (1) ERK (1) Fluorescent Dye (1) GLUT (1) HSP (1) Interleukin Related (1) PI3K (1) Prolyl Endopeptidase (PREP) (4) Radionuclide-Drug Conjugates (RDCs) (6) Reference Standards (1)
By Research Areas:	Cancer (61) Inflammation/Immunology (6) Metabolic Disease (3)

Inhibitors & Agonists

Fluorescent Dye

Peptides

Inhibitory Antibodies

Antibodies

Targets Recommended: FAP

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-13233A

Talabostat mesylate Maximum Cited Publications 42 Publications Verification Val-boroPro mesylate; PT100 mesylate	Dipeptidyl Peptidase	Inflammation/Immunology Cancer
Talabostat mesylate (Val-boroPro mesylate; PT100 mesylate) is an orally active and nonselective dipeptidyl peptidase IV (DPP-IV) inhibitor (IC₅₀ < 4 nM; K_i = 0.18 nM) and the inhibitor of fibroblast activation protein (FAP) (IC₅₀ = 560 nM), inhibits DPP8/9 (IC₅₀ = 4/11 nM; K_i = 1.5/0.76 nM), quiescent cell proline dipeptidase (QPP) (IC₅₀ = 310 nM), DPP2, and some other DASH family enzymes. Antineoplastic and hematopoiesis- stimulating activities .

HY-128643

FAPI-4 30+ Cited Publications	FAP	Cancer
FAPI-4 is a potent **fibroblast activation protein (FAP**) inhibitor for the targeting FAP. FAPI-4 can be used in cancer research. ⁶⁸Ga-FAPI-4 PET/CT is a promising new diagnostic method for imaging various kinds of cancer, with good tumor-to-background contrast ratios .

HY-100684

UAMC-1110 2 Publications Verification	Prolyl Endopeptidase (PREP) FAP	Cancer
UAMC-1110 is a highly potent and selective inhibitor of fibroblast activation protein (FAP) with an IC₅₀ of 3.2 nM. UAMC-1110 also inhibits prolyl oligopeptidase (PREP) with an IC₅₀ of 1.8 μM .

HY-137331

FAPI-46 2 Publications Verification	FAP	Cancer
FAPI-46 is a quinoline-based fibroblast activation protein (FAP)-targeted tracer. Use radioactivity FAPI-46 labeled with ⁶⁸Ga or ¹⁷⁷Lu can be used for tumor imaging in a variety of cancers and has higher tumor uptake rates and longer tumor accumulation .

HY-P99269

Sibrotuzumab 1 Publications Verification BIBH 1; Anti-Human FAP Recombinant Antibody	FAP	Cancer
Sibrotuzumab (BIBH 1) is a humanized IgG1 monoclonal antibody targets fibroblast activation protein (FAP). Sibrotuzumab can be used for the research of colorectal cancer and non-small cell lung cancer (NSCLC) .

HY-147173

FAPI-74	FAP	Cancer
FAPI-74 is a PET (positron emission tomography) tracer targeting the fibroblast activation protein (FAP). FAPI-74 can be used for FAP-positive tumor research .

HY-47979

FAP-IN-2 1 Publications Verification	FAP	Cancer
FAP-IN-2 is an isonitrile-containing fibroblast activation protein (FAP) inhibitor. FAP-IN-2 can be labeled with technetium-99m ( ^99mTc) for targeted tumor SPECT imaging .

HY-13233

Talabostat Val-boroPro; PT100	Dipeptidyl Peptidase	Inflammation/Immunology Cancer
Talabostat (Val-boroPro; PT100) is an orally active and nonselective dipeptidyl peptidase IV (DPP-IV) inhibitor (IC₅₀ < 4 nM; K_i = 0.18 nM) and the first clinical inhibitor of fibroblast activation protein (FAP) (IC₅₀ = 560 nM), inhibits DPP8/9 (IC₅₀ = 4/11 nM; K_i = 1.5/0.76 nM), quiescent cell proline dipeptidase (QPP) (IC₅₀ = 310 nM), DPP2, and some other DASH family enzymes. Antineoplastic and hematopoiesis- stimulating activities .

HY-145938

OncoFAP	FAP	Cancer
OncoFAP is an ultra-high-affinity ligand of fibroblast activation protein (FAP) for targeting applications with pan-tumoral potential.

HY-136641

NOTA-FAPI	Radionuclide-Drug Conjugates (RDCs) FAP	Cancer
NOTA-FAPI is a **fibroblast activation protein (FAP**) inhibitor. NOTA-FAPI can be used as a probe for FAP-targeted tumour imaging. NOTA-FAPI has good tumour detection efficacy and excellent imaging quality .

HY-P10944

Unlabeled FXX489 NNS309	FAP	Inflammation/Immunology Cancer
Unlabeled FXX489 (NNS309) is a fibroblast activation protein (FAP)-targeting ligand. Unlabeled FXX489 can be labeled with ⁶⁸Ga and ¹⁷⁷Lu and shows anticancer effects. Unlabeled FXX489 can be used for the study of pancreatic ductal adenocarcinoma (PDAC), non-small cell lung cancer (NSCLC), breast cancer (BC), and colorectal cancer (CRC) .

HY-P10945

FAP targeting peptide for FXX489	Radionuclide-Drug Conjugates (RDCs) FAP	Cancer
FAP targeting peptide for FXX489 is the polypeptide part of Unlabeled FXX489 (HY-P10944). Unlabeled FXX489 is a fibroblast activation protein (FAP)-targeting ligand .

HY-145983

Suc-Gly-Pro-AMC 1 Publications Verification	FAP Prolyl Endopeptidase (PREP)	Cancer
Suc-Gly-Pro-AMC is a fluorescent substrate. Suc-Gly-Pro-AMC is a fibroblast activation protein (FAP) specific substrate. Suc-Gly-Pro-AMC reacts with recombinant porcine prolyl oligopeptidase. Suc-Gly-Pro-AMC can be used to study the activity of FAP, prolyl endopeptidase (PREP). Suc-Gly-Pro-AMC is used in glioma research .

HY-153552A

NH2-UAMC1110 TFA	FAP	Cancer
NH2-UAMC1110 TFA is an aminobutoxy derivative of the fibroblast activation protein (FAP) inhibitor UAMC1110 (HY-100684), and is a precursor compound for the synthesis of FAP inhibitor probes, not directly used in bioactivity experiments. For example, NH2-UAMC1110 TFA is involved in the synthesis of the radiotracer FAPI-QS, which exhibits high tumor selectivity and high dose effect, and has been used in tumor diagnosis. NH2-UAMC1110 TFA structurally incorporates an active amino group, allowing it to form covalent bonds with various molecules (such as DOTA, DATA5m, radionuclide chelators, etc.) to synthesize molecular imaging probes or targeted compounds with the ability to target FAP. NH2-UAMC1110 TFA specifically binds to the FAP active site, inhibiting its proline-selective serine protease activity (including dipeptidyl peptidase and endopeptidase activity), blocking FAP-mediated tissue remodeling-related processes. Its key activity is high targeting and high affinity, and its core function is to act as a targeting module coupled with bifunctional chelators (such as DOTA, DATA5m). NH2-UAMC1110 TFA can be applied to diagnostic imaging studies of tumors expressing FAP (such as colorectal cancer, pancreatic cancer, etc.), and also provides molecular tools for targeted research of FAP-related diseases with high FAP expression, such as fibrosis and arthritis .

HY-148127

TAM558	Drug-Linker Conjugates for ADC	Cancer
TAM558 is a payload molecule used for the synthesis of OMTX705. OMTX705 is a humanized anti-fibroblast-activating *protein* (FAP) antibody conjugated to the cytolysin TAM470 (HY-148128), with antitumor activity .

HY-P99902

Simlukafusp alfa FAP-IL2v; RO6874281; RG7461	Interleukin Related	Cancer
Simlukafusp alfa (FAP-IL2v) is an immunocytokine comprising an antibody against fibroblast activation protein α (FAPα) and an IL-2 variant that only binds IL-2Rβγ. Isotype: human IgG1 .

HY-153552

NH2-UAMC1110	FAP	Cancer
NH2-UAMC1110 is an aminobutoxy derivative of the fibroblast activation protein (FAP) inhibitor UAMC1110 (HY-100684), and is a precursor compound for the synthesis of FAP inhibitor probes, not directly used in bioactivity experiments. For example, NH2-UAMC1110 is involved in the synthesis of the radiotracer FAPI-QS, which exhibits high tumor selectivity and high dose-response, and has been used for tumor diagnosis. NH2-UAMC1110 introduces an active amino group into its structure, enabling it to form covalent bonds with various molecules (such as DOTA, DATA5m, radionuclide chelators, etc.), thereby synthesizing molecular imaging probes or targeted compounds with the ability to target FAP. NH2-UAMC1110 specifically binds to the FAP active site, inhibiting its proline-selective serine protease activity (including dipeptidyl peptidase and endopeptidase activity), blocking FAP-mediated tissue remodeling processes. Its key activity is high targeting and high affinity, and its core function is to be coupled with bifunctional chelators (such as DOTA, DATA5m) as a targeting module. NH2-UAMC1110 can be applied to diagnostic imaging studies of tumors expressing FAP (such as colorectal cancer, pancreatic cancer, etc.), and also provides molecular tools for targeted research of FAP-related diseases with high FAP expression, such as fibrosis and arthritis .

HY-160289

ARI-3144	FAP	Cancer
ARI-3144 is an excellent and specific substrate for fibroblast activation protein (FAP). ARI-3144 is usually coupled with the fluorophore 7-Amino-4-methylcoumarin (HY-D0027) (AMC) for detection and quantification of FAP .

HY-125366

ARI-3099	FAP	Metabolic Disease
ARI-3099 is an oral fibroblast activation protein (FAP) inhibitor. ARI-3099 specifically inhibits the proteolytic activity of FAP and blocks the cleavage of human FGF-21 between residues P171 and S172. ARI-3099 extends the half-life of circulating human FGF-21 in mice. ARI-3099 can be used in the research of type 2 diabetes and metabolic disorders .

HY-161074

PNT6555	FAP	Cancer
PNT6555 is a fibroblast activation protein-α (FAP) inhibitor. PNT6555 has antitumor activity. PNT6555 can be used for imaging of FAP-positive tumors .

HY-P3441A

3BP-4089 TFA	FAP	Cancer
3BP-4089 TFA is a highly efficient fibroblast activation protein (FAP) targeting peptide. 3BP-4089 TFA is often conjugated with radionuclides for tumor diagnosis and research .

HY-W404002

BR102910	Prolyl Endopeptidase (PREP)	Metabolic Disease
BR102910 is a selective fibroblast activation protein (FAP) inhibitor with the IC₅₀ of 2 nM. BR102910 also inhibits prolyl oligopeptidase (PREP) with the IC₅₀ of 49.00 μM. BR102910 can be used for the researchof type 2

HY-162334

HYOU1-IN-1	HSP	Inflammation/Immunology Cancer
HYOU1-IN-1 (Compound 33) is an inhibitor of hypoxia-upregulated protein 1 (HYOU1) with anti-inflammatory activity. HYOU1-IN-1 can be used in research on the regulation of fibroblast activation, chronic inflammation, and fibrotic diseases .

HY-173374

DOTAGA-FAP-2286-ALB	FAP Drug Derivative	Cancer
DOTAGA-FAP-2286-ALB is a derivative of Rofapitide tetraxetan (HY-147057). DOTAGA-FAP-2286-ALB is a selective fibroblast activation protein (FAP) inhibitor with an IC₅₀ value of 67.5 nM. DOTAGA-FAP-2286-ALB enhances tumor retention via albumin interaction, prolonging blood circulation and improving radiometal complex stability (e.g., with 111In and 225Ac). DOTAGA-FAP-2286-ALB is promising for research of radionuclide therapy (TRT) of FAP-positive solid tumors .

HY-177435

FAPI-800CW	FAP	Inflammation/Immunology
FAPI-800CW is a near-infrared (NIR) fluorescent-labeled fibroblast activation protein (FAP) inhibitor. FAPI-800CW shows specific uptake in inflamed paws in collagen-induced arthritis (CIA) model mice. FAPI-800CW can be used for in vivo molecular imaging of FAP expression in inflammatory diseases such as rheumatoid arthritis (RA) to monitor joint inflammation and disease activity .

HY-177459

DOTA-2P(FAPI)2	FAP	Cancer
DOTA-2P(FAPI)2 is a dimeric FAP (fibroblast activation protein) that can be used as a PET imaging agent and a tracer for tumor therapy .

HY-P3441

3BP-4089	FAP	Cancer
3BP-4089 is a highly efficient fibroblast activation protein (FAP) targeting peptide. 3BP-4089 is often conjugated with radionuclides for tumor diagnosis and research .

HY-176958

OncoFAP-EN-DOTAGA	FAP	Others
OncoFAP-EN-DOTAGA is a FAP (fibroblast activation protein) targeting conjugate compound. OncoFAP-EN-DOTAGA can chelate radioactive isotopes (such as ) Ga-68 or fluorescent agent and can be used as a probe with targeting binding functions .

HY-177083

Faridoxorubicin AVA-6000	FAP	Cancer
Faridoxorubicin (AVA-6000) is a prodrug targeting fibroblast activation protein α (FAPα). Faridoxorubicin releases active doxorubicin through FAPα-mediated cleavage, enhancing intratumoral drug exposure and reducing cardiac toxicity. Faridoxorubicin is promising for research of solid tumors (e.g., colorectal cancer liver metastasis) .

HY-164725

FAPI-mFS	Radionuclide-Drug Conjugates (RDCs) FAP	Cancer
FAPI-mFS is an irreversible fibroblast activation protein (FAP) inhibitor, that enhances the uptake and retention time in cancer cells through its covalent binding property for FAP. FAPI-mFS can be used for cancer imaging the therapy, when labeled with radioactive 68Ga or 177Lu . FAPI-mFS can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-164364A

DOTAGA.(SA.FAPi)2 TFA	FAP	Cancer
DOTAGA.(SA.FAPi)2 TFA is a potent dimeric **fibroblast-activation protein inhibitor (FAPi**). DOTAGA.(SA.FAPi)2 TFA has the potential for cancer diagnosis research .

HY-W668749

3BP-3580	FAP	Cancer
3BP-3580 is a fibroblast activation protein (FAP) inhibitor (pIC₅₀: 8.6), and can be used for cancer research .

HY-149860

FAP-IN-1	FAP	Cancer
FAP-IN-1 is a fibroblast activation protein (FAP) inhibitor with an IC₅₀ value of 3.3 nM. FAP-IN-1 can be used for the research of cancer .

HY-47979A

FAP-IN-2 TFA 1 Publications Verification	FAP	Cancer
FAP-IN-2 TFA is an isonitrile-containing fibroblast activation protein (FAP) inhibitor. FAP-IN-2 TFA can be labeled with technetium-99m ( ^99mTc) for targeted tumor SPECT imaging .

HY-D2281

FAP Ligand 2	FAP	Cancer
FAP Ligand 2, a FAPI-46 derivative, is a specific fibroblast activation protein (FAP)-targeted tracer. FAP Ligand 2 exhibits good tumor uptake and acts as a promising molecular tracer for FAP tumor imaging .

HY-175322

FAPI-P8PN	FAP	Cancer
FAPI-P8PN is a fibroblast activation protein (FAP) inhibitor (IC₅₀=3.6 nM). FAPI-P8PN is promising for research of FAP-overexpressing solid tumors .

HY-175353

TriOncoFAP-GlyPro-MMAE	FAP	Cancer
TriOncoFAP-GlyPro-MMAE is a small molecule drug conjugate (SMDC) targeting fibroblast activation protein (FAP) with an IC₅₀ of 13 pmol/L. TriOncoFAP-GlyPro-MMAE combines a FAP-targeting ligand (TriOnco), a cleavable glycine-proline linker, and a cytotoxic payload (MMAE) .

HY-145358

FAP-PI3KI1	PI3K	Cancer
FAP-PI3KI1 is a fibroblast-activated protein (FAP)-targeted PI3K inhibitor that selectively targets FAP-expressing human idiopathic pulmonary fibrosis (IPF) cells and effectively inhibits collagen synthesis and reduces collagen deposition .

HY-128642

FAPI-2	FAP	Cancer
FAPI-2 is a quinoline-based fibroblast activation protein (FAP)-targeting ligand that can be labeled as ⁶⁸Ga-FAPI-2 and used as a PET tracer for cancer diagnosis. FAPI-2 has advantages such as fast tracer kinetics, no need for fasting preparation, and being unaffected by blood glucose .

HY-174421

FAPI-JNU	FAP	Cancer
FAPI-JNU is a molecule targeting fibroblast activation protein (FAP). FAPI-JNU specifically binds to FAP highly expressed in the tumor microenvironment, and uses radionuclides [ ⁶⁸Ga]Ga or [ ¹⁷⁷Lu]Lu to achieve tumor imaging diagnosis. [177Lu]Lu−FAPI−JNU can effectively target and inhibit tumor growth in tumor-bearing mice. FAPI-JNU is promising for research of FAP-positive tumors (such as various solid tumors) .

HY-164364B

DOTAGA.(SA.FAPi)2 analogue TFA	FAP	Cancer
DOTAGA.(SA.FAPi)2 analogue TFA is a DOTAGA.(SA.FAPi)2 TFA (HY-164364A) analogue, in which the ligand and the chelator are identical to those of DOTAGA.(SA.FAPi)2 TFA. DOTAGA.(SA.FAPi)2 TFA is a potent dimeric fibroblast-activation protein inhibitor (FAPi) .

HY-161262

SB03178	FAP	Cancer
SB03178 is a fibroblast activation protein-alpha (FAP) inhibitor. SB03178 can be conjugated with DOTA and can be used for cancer research .

HY-172137

FAPI-FUSCC-07	FAP	Cancer
FAPI-FUSCC-07 is a targeted probe for fibroblast activation protein (FAP), exhibiting high affinity binding to FAP for applications in molecular imaging, tumor diagnosis, and radiotherapy .

HY-P10945B

Cys-FAP targeting peptide for FXX489 TFA	Radionuclide-Drug Conjugates (RDCs) FAP	Cancer
Cys-FAP targeting peptide for FXX489 TFA is the polypeptide part of Unlabeled FXX489 (HY-P10944). Unlabeled FXX489 is a fibroblast activation protein (FAP)-targeting ligand .

HY-158326

FAP-IN-4	FAP	Cancer
FAP-IN-4 (Comp 10) is a fibroblast activation protein (FAP) inhibitor and a ¹⁸F-labeled PET tracer targeting FAP. FAP-IN-4 can be used for cancer research .

HY-169868

NOTA-FAPI-52	Biochemical Assay Reagents	Cancer
NOTA-FAPI-52 is a tracer with potent tumor uptake. NOTA-FAPI-52 can be radiolabeled to enable PET imaging or other bioimaging techniques. NOTA-FAPI-52 can be used to study diseases in which fibroblast activation protein (FAP) is overexpressed .

HY-P10946

FAP targeting peptide-PEG2 conjugate	Radionuclide-Drug Conjugates (RDCs)	Cancer
FAP targeting peptide-PEG2 conjugate (Example A1) is the peptide (HY-P10945) and linker conjugate of Unlabeled FXX489 (HY-P10944). Unlabeled FXX489 is a fibroblast activation protein (FAP)-targeting ligand .

HY-128642A

FAPI-2 TFA	FAP	Cancer
FAPI-2 TFA is a quinoline-based fibroblast activation protein (FAP)-targeting ligand that can be labeled as ⁶⁸Ga-FAPI-2 and used as a PET tracer for cancer diagnosis. FAPI-2 TFA has advantages such as fast tracer kinetics, no need for fasting preparation, and being unaffected by blood glucose .

HY-159934

QI-18	FAP	Cancer
QI-18 is a fibroblast activation protein (FAP) inhibitor with the IC₅₀ of 0.50 nM, which is a 6.5-fold increase in potency over that of UAMC-1110 (HY-100684，IC₅₀ of 3.25 nM). QI-18 can be used to synthesize high tumor selectivity and high dose radiotracers for the diagnosis and study of tumors .

HY-159771

FAP6-19	FAP	Cancer
FAP6-19 is a fibroblast activation protein (FAP) targeting radioligand with a K_d of 18.2 nM. FAP6-19 selectively delivers therapeutic radioactive nuclides (such as 177Lu) to the tumor site by targeting the overexpressed FAP protein in the tumor microenvironment, achieving precise killing of cancer cells while minimizing radiation damage to healthy tissues. FAP6-19 exhibits extremely high total cellular uptake and good intracellular retention ability in HT1080 cells. After being labeled with 111In, FAP6-19 produced extremely high tumor/kidney and tumor/liver dose ratios in the mouse model with 4T1 tumors. FAP6-19 can be used in the research of solid tumors expressing FAP.

Cat. No.	Product Name	Target	Research Area

HY-P10944

Unlabeled FXX489 NNS309	FAP	Inflammation/Immunology Cancer
Unlabeled FXX489 (NNS309) is a fibroblast activation protein (FAP)-targeting ligand. Unlabeled FXX489 can be labeled with ⁶⁸Ga and ¹⁷⁷Lu and shows anticancer effects. Unlabeled FXX489 can be used for the study of pancreatic ductal adenocarcinoma (PDAC), non-small cell lung cancer (NSCLC), breast cancer (BC), and colorectal cancer (CRC) .

HY-P10945

FAP targeting peptide for FXX489	Radionuclide-Drug Conjugates (RDCs) FAP	Cancer
FAP targeting peptide for FXX489 is the polypeptide part of Unlabeled FXX489 (HY-P10944). Unlabeled FXX489 is a fibroblast activation protein (FAP)-targeting ligand .

HY-P3441A

3BP-4089 TFA	FAP	Cancer
3BP-4089 TFA is a highly efficient fibroblast activation protein (FAP) targeting peptide. 3BP-4089 TFA is often conjugated with radionuclides for tumor diagnosis and research .

HY-P3441

3BP-4089	FAP	Cancer
3BP-4089 is a highly efficient fibroblast activation protein (FAP) targeting peptide. 3BP-4089 is often conjugated with radionuclides for tumor diagnosis and research .

HY-164725

FAPI-mFS	Radionuclide-Drug Conjugates (RDCs) FAP	Cancer
FAPI-mFS is an irreversible fibroblast activation protein (FAP) inhibitor, that enhances the uptake and retention time in cancer cells through its covalent binding property for FAP. FAPI-mFS can be used for cancer imaging the therapy, when labeled with radioactive 68Ga or 177Lu . FAPI-mFS can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-P10945B

Cys-FAP targeting peptide for FXX489 TFA	Radionuclide-Drug Conjugates (RDCs) FAP	Cancer
Cys-FAP targeting peptide for FXX489 TFA is the polypeptide part of Unlabeled FXX489 (HY-P10944). Unlabeled FXX489 is a fibroblast activation protein (FAP)-targeting ligand .

HY-P10946

FAP targeting peptide-PEG2 conjugate	Radionuclide-Drug Conjugates (RDCs)	Cancer
FAP targeting peptide-PEG2 conjugate (Example A1) is the peptide (HY-P10945) and linker conjugate of Unlabeled FXX489 (HY-P10944). Unlabeled FXX489 is a fibroblast activation protein (FAP)-targeting ligand .

HY-159771

FAP6-19	FAP	Cancer
FAP6-19 is a fibroblast activation protein (FAP) targeting radioligand with a K_d of 18.2 nM. FAP6-19 selectively delivers therapeutic radioactive nuclides (such as 177Lu) to the tumor site by targeting the overexpressed FAP protein in the tumor microenvironment, achieving precise killing of cancer cells while minimizing radiation damage to healthy tissues. FAP6-19 exhibits extremely high total cellular uptake and good intracellular retention ability in HT1080 cells. After being labeled with 111In, FAP6-19 produced extremely high tumor/kidney and tumor/liver dose ratios in the mouse model with 4T1 tumors. FAP6-19 can be used in the research of solid tumors expressing FAP.

HY-P4448

Ac-Gly-Pro-AFC	Fluorescent Dye	Others
Ac-Gly-Pro-AFC is a fluorogenic substrate for the determination of fibroblast activation protein (FAP) endopeptidase activity .

HY-P10945A

Cys-FAP targeting peptide for FXX489	Radionuclide-Drug Conjugates (RDCs) FAP	Cancer
Cys-FAP targeting peptide for FXX489 is the polypeptide part of Unlabeled FXX489 (HY-P10944). Unlabeled FXX489 is a fibroblast activation protein (FAP)-targeting ligand .

HY-P11599

NOTA-SP2A-FAPT	FAP	Cancer
NOTA-SP2A-FAPT is a **fibroblast activation protein (FAP**) ligand. NOTA-SP2A-FAPT can be adiolabeled and exhibits rapid renal excretion with fast kidney tissue clearance, accumulates rapidly in and retains high levels in FAP-positive tumor xenografts to enable clear tumor visualization. NOTA-SP2A-FAPT can be used as a tracer of cancer .

HY-P11602

DOTA-C1-FAP-2286	FAP	Cancer
DOTA-C1-FAP-2286 is a cysteic acid-modified fibroblast activation protein (FAP)-targeting radioligand. DOTA-C1-FAP-2286 binds competitively to FAP with an IC₅₀ of 127.64 nM. DOTA-C1-FAP-2286 is targeted accumulation in FAP-expressing cells and exhibits accelerated renal clearance. DOTA-C1-FAP-2286 can be used as a PET/CT tracer in cancer .

Cat. No.	Product Name	Target	Research Area	Image

HY-P99269

Sibrotuzumab 1 Publications Verification BIBH 1; Anti-Human FAP Recombinant Antibody	FAP	Cancer
Sibrotuzumab (BIBH 1) is a humanized IgG1 monoclonal antibody targets fibroblast activation protein (FAP). Sibrotuzumab can be used for the research of colorectal cancer and non-small cell lung cancer (NSCLC) .

HY-P99902

Simlukafusp alfa FAP-IL2v; RO6874281; RG7461	Interleukin Related	Cancer
Simlukafusp alfa (FAP-IL2v) is an immunocytokine comprising an antibody against fibroblast activation protein α (FAPα) and an IL-2 variant that only binds IL-2Rβγ. Isotype: human IgG1 .

Host:	Mouse (1) Rabbit (5)
Reactivity:	Human (6)
Application:	IHC-P (4) ICC/IF (1) IP (1) WB (5) FC (1) ELISA (2)
Isotype:	IgG (4) IgG1 (1) IgG/Kappa (1)
Conjugation:	Non-conjugated (6)
Clonality:	Monoclonal (4) Recombinant (1)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P86341

	FAP Antibody (YA6033) Seprase; 170 kDa melanoma membrane-bound gelatinase; fibroblast activation protein alpha; Integral membrane serine protease;	WB, IHC-P, ICC/IF, IP, ELISA	Human
	FAP Antibody (YA6033) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FAP.

HY-P81345

	FAP Antibody (YA1090) FAP; Seprase; 170 kDa melanoma membrane-bound gelatinase; fibroblast activation protein alpha; Integral membrane serine protease	WB, IHC-P	Human
	FAP Antibody (YA1090) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FAP.

HY-P81697

	FAP Antibody (YA1442) FAP; Seprase; 170 kDa melanoma membrane-bound gelatinase; fibroblast activation protein alpha; Integral membrane serine protease	IHC-P, FC, ELISA	Human
	FAP Antibody (YA1442) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to FAP.

HY-P81345A

	FAP Antibody (YA1090)(PBS only) FAP; Seprase; 170 kDa melanoma membrane-bound gelatinase; fibroblast activation protein alpha; Integral membrane serine protease	WB, IHC-P	Human
	FAP Antibody (YA1090) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FAP.

HY-P86673

	FAP Antibody (YA6365) Prolyl endopeptidase FAP; FAPA; fibroblast activation protein, alpha; 170 kDa melanoma membrane bound gelatinase; 170 kDa melanoma membrane-bound gelatinase; DPPIV; fibroblast activation protein alpha; Integral membrane serine protease; SEPR_HUMAN; 170 kDa melanoma membrane-bound gelatinase; Dipeptidyl peptidase FAP; FAPalpha; Gelatine degradation protease FAP; Integral membrane serine protease; Post-proline cleaving enzyme; Serine integral membrane protease; SIMP; Surface-expressed protease; Seprase; Antiplasmin-cleaving enzyme FAP, soluble form; APCE.	WB	Human
	FAP Antibody (YA6365) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FAP.

HY-P86673A

	FAP Antibody (YA6365)(PBS only) Prolyl endopeptidase FAP; FAPA; fibroblast activation protein, alpha; 170 kDa melanoma membrane bound gelatinase; 170 kDa melanoma membrane-bound gelatinase; DPPIV; fibroblast activation protein alpha; Integral membrane serine protease; SEPR_HUMAN; 170 kDa melanoma membrane-bound gelatinase; Dipeptidyl peptidase FAP; FAPalpha; Gelatine degradation protease FAP; Integral membrane serine protease; Post-proline cleaving enzyme; Serine integral membrane protease; SIMP; Surface-expressed protease; Seprase; Antiplasmin-cleaving enzyme FAP, soluble form; APCE.	WB	Human
	FAP Antibody (YA6365) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FAP.

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