1802499-21-3
Chemical Structure
TAM558
- CAS No.: 1802499-21-3
- Formula:C79H122N14O19S
- Molecular Weight:1603.96
IUPAC Name: 1-(4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)phenyl)-3-oxo-2,7,10,13-tetraoxa-4-azapentadecan-15-yl 2-((2S,4R)-5-(4-hydroxyphenyl)-2-methyl-4-(2-((1R,3R)-4-methyl-3-((2S,3S)-3-methyl-2-((R)-1-methylpiperidine-2-carboxamido)-N-propylpentanamido)-1-propoxypentyl)thiazole-4-carboxamido)pentanoyl)hydrazine-1-carboxylate
InChIKey: GJSOQVVIEZWQBH-FOJMMPRNSA-N
SMILES: O=C([C@@H]1N(CCCC1)C)N[C@@H]([C@@H](C)CC)C(N(CCC)[C@@H](C(C)C)C[C@H](C2=NC(C(N[C@H](C[C@H](C)C(NNC(OCCOCCOCCOCCNC(OCC3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN4C(C=CC4=O)=O)=O)=O)=O)=O)=O)=O)CC5=CC=C(C=C5)O)=O)=CS2)OCCC)=O
Biological Activity: TAM558 is a payload molecule used for the synthesis of OMTX705. OMTX705 is a humanized anti-fibroblast-activating protein (FAP) antibody conjugated to the cytolysin TAM470 (HY-148128), with antitumor activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TAM558 | 99.48% | TAM558 is a payload molecule used for the synthesis of OMTX705. OMTX705 is a humanized anti-fibroblast-activating protein (FAP) antibody conjugated to the cytolysin TAM470 (HY-148128), with antitumor activity. | ||||||||||||||||||||
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Keywords
