1448440-52-5
1448440-52-5
Chemical Structure
UAMC-1110
- CAS. Nr.: 1448440-52-5
- Formula:C17H14F2N4O2
- Molecular Weight:344.32
IUPAC Name: (S)-N-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide
InChIKey: PUOOCZVRHBHJRS-NSHDSACASA-N
SMILES: O=C(C1=CC=NC2=CC=CC=C12)NCC(N3[C@H](C#N)CC(F)(F)C3)=O
Biological Activity: UAMC-1110 is a highly potent and selective inhibitor of fibroblast activation protein (FAP) with an IC50 of 3.2 nM. UAMC-1110 also inhibits prolyl oligopeptidase (PREP) with an IC50 of 1.8 μM[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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UAMC-1110 | 99.51% | UAMC-1110 is a highly potent and selective inhibitor of fibroblast activation protein (FAP) with an IC50 of 3.2 nM. UAMC-1110 also inhibits prolyl oligopeptidase (PREP) with an IC50 of 1.8 μM. | ||||||||||||||||||||
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UAMC-1110 (Standard) | ≥98% | UAMC-1110 (Standard) is the analytical standard of UAMC-1110 (HY-100684). This product is intended for research and analytical applications. UAMC-1110 is a highly potent and selective inhibitor of fibroblast activation protein (FAP) with an IC50 of 3.2 nM. UAMC-1110 also inhibits prolyl oligopeptidase (PREP) with an IC50 of 1.8 μM. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.81
HY-184826FAP Ligand-4 -
Similarity Score 0.73
HY-153552NH2-UAMC1110 -
Similarity Score 0.68
HY-153552ANH2-UAMC1110 TFA -
Similarity Score 0.68
HY-47979FAP-IN-2 -
Similarity Score 0.67
HY-145938OncoFAP -
Similarity Score 0.66
HY-164316FT-FAPI-12_9 -
Similarity Score 0.61
HY-W6687493BP-3580 -
Similarity Score 0.61
HY-175685FAP-IN-7 -
Similarity Score 0.59
HY-158326FAP-IN-4 -
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