1448440-52-5
1448440-52-5
Chemical Structure
UAMC-1110
- CAS No.: 1448440-52-5
- Formula:C17H14F2N4O2
- Molecular Weight:344.32
IUPAC Name: (S)-N-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide
InChIKey: PUOOCZVRHBHJRS-NSHDSACASA-N
SMILES: O=C(C1=CC=NC2=CC=CC=C12)NCC(N3[C@H](C#N)CC(F)(F)C3)=O
Biological Activity: UAMC-1110 is a highly potent and selective inhibitor of fibroblast activation protein (FAP) with an IC50 of 3.2 nM. UAMC-1110 also inhibits prolyl oligopeptidase (PREP) with an IC50 of 1.8 μM[1].
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UAMC-1110 | 99.51% | UAMC-1110 is a highly potent and selective inhibitor of fibroblast activation protein (FAP) with an IC50 of 3.2 nM. UAMC-1110 also inhibits prolyl oligopeptidase (PREP) with an IC50 of 1.8 μM. | ||||||||||||||||||||
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UAMC-1110 (Standard) | ≥98% | UAMC-1110 (Standard) is the analytical standard of UAMC-1110 (HY-100684). This product is intended for research and analytical applications. UAMC-1110 is a highly potent and selective inhibitor of fibroblast activation protein (FAP) with an IC50 of 3.2 nM. UAMC-1110 also inhibits prolyl oligopeptidase (PREP) with an IC50 of 1.8 μM. | ||||||||||||||||||||
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References
Keywords
