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Results for "

frog skin

" in MedChemExpress (MCE) Product Catalog:

26

Inhibitors & Agonists

1

Biochemical Assay Reagents

22

Peptides

4

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P0270
    Magainin 2

    Magainin II

    		 Bacterial Antibiotic Fungal Infection
    Magainin 2 (Magainin II) is an antimicrobial peptide (AMP) isolated from the skin of the African clawed frog Xenopus laevis. Magainin 2 displays antibiotic activity against numerous gram-negative and gram-positive bacteria. Magainin 2 also is active against protozoa . Magainin 2 exerts its cytotoxicity effects by preferential interactions with anionic phospholipids abundant in bacterial membranes .
    Magainin 2
  • HY-P0263
    Dermaseptin

    		Bacterial Fungal Antibiotic Infection
    Dermaseptin, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi, and protozoa at micromolar concentration .
    Dermaseptin
  • HY-P1629
    Temporin A

    		Bacterial Fungal Antibiotic Infection
    Temporin A is a short alpha-helical antimicrobial peptide isolated from the skin of the frog Rana temporaria. Temporin A is effective against a broad spectrum of Gram-positive bacteria. Temporin A interacts directly with the cell membrane of the microorganism and it is non-toxic to erythrocytes at concentrations that are antimicrobial. Temporin A also has antifungal activities (against yeast-like Candida albicans) .
    Temporin A
  • HY-P3443
    Peanut agglutinin
    1 Publications Verification

    PNA

    		 Biochemical Assay Reagents Cancer
    Peanut agglutinin (PNA) is a carbohydrate-recognition protein that binds competitively and irreversibly to cell-surface β-D-Gal (1-3)-GalNAc, and this binding can be inhibited by D-galactose and asialofetuin. Peanut agglutinin recognizes exposed glycoepitopes and reflects the glycosylation status of cells. Peanut agglutinin can label glycoconjugates at neuromuscular junctions to safely visualize synaptic structures. Peanut agglutinin can be used to synthesize dyes to distinguish between normal and tumor tissues. Peanut agglutinin provides support for research on leukemia, Burkitt's tumors, and cutaneous squamous lesions .
    Peanut agglutinin
  • HY-P3915
    Esculentin 1A

    		Bacterial Infection
    Esculentin 1A is a frog skin-derived antimicrobial peptide (AMP) with potent in vitro anti-Pseudomonas activity .
    Esculentin 1A
  • HY-P5594
    Dermaseptin-S1

    		Fungal Infection
    Dermaseptin-S1 is an antimicrobial peptide derived from frog skin against filamentous fungi .
    Dermaseptin-S1
  • HY-P0274
    PGLa

    		Bacterial Antibiotic Infection
    PGLa, a 21-residue peptide, is an antimicrobial peptide. PGLa is a member of the magainin family of antibiotic peptides found in frog skin and its secretions .
    PGLa
  • HY-P3645
    (Nle4)-α-MSH

    		Melanocortin Receptor Others
    (Nle4)-α-MSH is a synthetic analogue of α-MSH (HY-P0252), a melanocyte-stimulating hormone. (Nle4)-α-MSH reversibly darkens frog skins and also exhibits prolonged activity after heat-alkali treatment .
    (Nle4)-α-MSH
  • HY-P4816
    Pseudin-2

    		Bacterial Fungal Infection Inflammation/Immunology
    Pseudin-2, an AMP thast could be isolated from the skin of the South American paradoxical frog Pseudis paradoxa, exert a potent growth inhibitory effect against Gram-negative bacteria .
    Pseudin-2
  • HY-P2706
    Granuliberin R

    		Histamine Receptor Endocrinology
    Granuliberin R is a new mast cell degranulating peptide comes from amphibian, can be isolated from the skin of frog Rana rugosa. Granuliberin R is a dodecapeptide, can act on rat peritoneal mast cell to liberate granules and release histamine .
    Granuliberin R
  • HY-129271
    Deltorphin

    Deltorphin A; Dermenkephalin

    		 Opioid Receptor Others
    Deltorphin (Deltorphin A; Dermenkephalin) is a biological active peptide. (Deltorphin A peptide was isolated from skin extracts of the South American frog, Phyllomedusa sauvagei. Deltorphin A is a potent and selective agonist for the delta-opioid receptor.)
    Deltorphin
  • HY-P1685
    Ranatensin

    		Bombesin Receptor Cardiovascular Disease Endocrinology
    Ranatensin is a undecapeptide and a Bombesin Receptor angonist, can be isolated from amphibian skin, such as the frog, Rana pipiens. Ranatensin could maintain the dynamic balance of animal blood pressure, without cross-tachyphylaxis with Angiotensin amide (HY-P2212),Bradykinin (HY-P0206), or Norepinephrine (HY-13715) .
    Ranatensin
  • HY-18612
    MK-7725

    		Bombesin Receptor Metabolic Disease
    MK-7725 is a selective, orally active, and blood-brain barrier-permeable agonist of the subtype 3 of the frog skin peptide receptor (BRS-3). MK-7725 has a high affinity for the human BRS-3 (hBRS-3), with an IC50 of 3 nM, and its functional activity in the mouse-derived BRS-3 (mBRS-3) model with an EC50 of 22 nM (105% agonistic). MK-7725 significantly reduces the body weight of obese rats and obese dogs. MK-7725 can be used for the treatment of obesity .
    MK-7725
  • HY-101078A
    (±)-Epibatidine dihydrochloride

    CMI 545 dihydrochloride

    		 Dopamine Receptor Neurological Disease
    (±)-Epibatidine (CMI 545) dihydrochloride is an agonist of nicotinic with potent analgetic activity. (±)-Epibatidine (CMI 545) dihydrochloride is an alkaloid originally characterized from frog skin. (±)-Epibatidine (CMI 545) dihydrochloride have little or no activity at a variety of other central receptors, including opioid receptors, muscarinic receptors, adrenergic receptors, dopamine receptors, serotonin receptors, and gamma-aminobutyric acid receptors .
    (±)-Epibatidine dihydrochloride
  • HY-P5587
    Dermaseptin-S5

    		Fungal Infection
    Dermaseptin-S5 is an antimicrobial peptide derived from frog skin against filamentous fungi .
    Dermaseptin-S5
  • HY-P5588
    Dermaseptin-S4

    		Fungal Infection
    Dermaseptin-S4 is an antimicrobial peptide derived from frog skin against filamentous fungi .
    Dermaseptin-S4
  • HY-P5590
    Dermaseptin-S3

    		Fungal Infection
    Dermaseptin-S3 is an antimicrobial peptide derived from frog skin against filamentous fungi .
    Dermaseptin-S3
  • HY-P5593
    Dermaseptin-S2

    		Fungal Infection
    Dermaseptin-S2 is an antimicrobial peptide derived from frog skin against filamentous fungi .
    Dermaseptin-S2
  • HY-P5585
    Dermaseptin-B4

    		Bacterial Infection
    Dermaseptin-B4 is an antimicrobial peptide derived from the skin secretions of the South American frog Phyllomedusa bicolor .
    Dermaseptin-B4
  • HY-P0263A
    Dermaseptin TFA

    		Bacterial Fungal Infection
    Dermaseptin TFA, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi, and protozoa at micromolar concentration .
    Dermaseptin TFA
  • HY-P0274A
    PGLa TFA

    		Bacterial Antibiotic Infection
    PGLa TFA, a 21-residue peptide, is an antimicrobial peptide. PGLa TFA is a member of the magainin family of antibiotic peptides found in frog skin and its secretions .
    PGLa TFA
  • HY-167657
    Tizolemide

    		Sodium Channel Cardiovascular Disease
    Tizolemide is a sulphonamide diuretic compound that has alkaline properties and is cleared by a tubular transport system. Tizolemide induces changes of passive transport components across the basolateral membrane of isolated frog skin .
    Tizolemide
  • HY-158702
    5-HTQ chloride

    		5-HT Receptor Neurological Disease
    5-HTQ chloride is an indole alkaloid that can be isolated from the skin secretions of the Australian golden bell frog Litoria aurea. 5-HTQ chloride is also a full agonist of the 5-HT receptor .
    5-HTQ chloride
  • HY-P5690
    Distinctin

    		Bacterial Infection
    Distinctin is an antimicrobial peptide. Distinctin can be isolated from frog skin. Distinctin has antibacterial activity against E. faecalis, P. aeruginosa, S. aureus and E. coli (MIC: 14.5, 28.0, 28.0, 14.5 μM) .
    Distinctin
  • HY-P2019
    Levitide

    		Neuropeptide Y Receptor Neurological Disease
    Levitide is a neurohormone-like peptide, can be isolated from skin secretions of the South African frog Xenopus laevis. Levitide comes from preprolevitide, is 88 residues long and contains contains the levitide peptide at the C terminus (Glu-Gly-Met-Ile-Gly-Thr-Leu-Thr-Ser-Lys-Arg-Ile-Lys-Gln-NH2) and the putative signal sequence at the N terminus .
    Levitide
  • HY-P3171
    Acetyl-(Cys4,D-Phe7,Cys10)-a-MSH (4-13)

    		Biochemical Assay Reagents Others
    Acetyl-(Cys4,D-Phe7,Cys10)-a-MSH (4-13) is a melanotropin cyclic peptide. Acetyl-(Cys4,D-Phe7,Cys10)-a-MSH (4-13) ultraprolongs melanotropic activity in frog and lizard skin model with great agonisim. Acetyl-(Cys4,D-Phe7,Cys10)-a-MSH (4-13) exhibits a complete resistance to tryptic degradation .
    Acetyl-(Cys4,D-Phe7,Cys10)-a-MSH (4-13)

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