Pseudin-2
Pseudin-2, an AMP thast could be isolated from the skin of the South American paradoxical frog Pseudis paradoxa, exert a potent growth inhibitory effect against Gram-negative bacteria.
For research use only. We do not sell to patients.
- CAS No.: 388602-02-6
- Formula: C122H202N36O32
- Molecular Weight:2685.13
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
The MICs of Pseudin-2 ranges from 2 to 4 μM (in low ionic strength buffer) against nearly all bacterial strains, except P. aeruginosa, against which it had a MIC of 8 μM. Pseudin-2 also exerts potent antimicrobial activity against antibioticresistant bacteria and pathogenic fungal cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 388602-02-6
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Molecular Weight 2685.13
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Formula C122H202N36O32
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Sequence
Gly-Leu-Asn-Ala-Leu-Lys-Lys-Val-Phe-Gln-Gly-Ile-His-Glu-Ala-Ile-Lys-Leu-Ile-Asn-Asn-His-Val-Gln
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Sequence Shortening
GLNALKKVFQGIHEAIKLINNHVQ
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Gram Staining of Tissue Sections
Gram staining of tissue sections is a histochemical technique used to differentiate Gram-positive and Gram-negative bacteria within histological specimens based on differences in bacterial cell wall structure and dye retention, adapted from classical bacteriological Gram staining into tissue-compatible “histological Gram stain” variants. In tissue applications, modifications of the Brown-Hopps and Brown-Brenn methods are commonly used to improve differentiation of microorganisms embedded within host connective tissue and to reduce overstaining or loss of Gram-negative signal, which are known limitations of earlier approaches. The principle relies on crystal violet-iodine complex retention in Gram-positive organisms and subsequent decolorization and counterstaining steps that allow contrast visualization of Gram-negative organisms against tissue background.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pseudin-2 Related Classifications
HY-P4816 Related Classifications
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