29451-71-6
29451-71-6
Chemical Structure
Ranatensin
- CAS. Nr.: 29451-71-6
- Formula:C61H84N16O13S
- Molecular Weight:1281.48
SMILES: O=C([C@H]1N(CCC1)C([C@H](C(C)C)NC([C@H]2NC(CC2)=O)=O)=O)N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@@H](C)C(N[C@@H](C(C)C)C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CCSC)=O)CC3=CC=CC=C3)=O)CC4=CN=CN4)=O)=O)=O)=O)CC5=CNC6=CC=CC=C56)=O
Biological Activity: Ranatensin is a undecapeptide and a Bombesin Receptor angonist, can be isolated from amphibian skin, such as the frog, Rana pipiens. Ranatensin could maintain the dynamic balance of animal blood pressure, without cross-tachyphylaxis with Angiotensin amide (HY-P2212),Bradykinin (HY-P0206), or Norepinephrine (HY-13715)[1][2].
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Ranatensin | Ranatensin is a undecapeptide and a Bombesin Receptor angonist, can be isolated from amphibian skin, such as the frog, Rana pipiens. Ranatensin could maintain the dynamic balance of animal blood pressure, without cross-tachyphylaxis with Angiotensin amide (HY-P2212),Bradykinin (HY-P0206), or Norepinephrine (HY-13715). | |||||||||||||||||||||
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References
- [1]. Jensen RT, et al. A synthetic peptide that is a bombesin receptor antagonist. Nature. 1984 May 3-9;309(5963):61-3. [Content Brief]
- [2]. Geller RG, et al. The action of ranatensin, a new polypeptide from amphibian skin, on the blood pressure of experimental animals. Br J Pharmacol. 1970 Dec;40(4):605-16. [Content Brief]
