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MK-7725

MK-7725 is a selective, orally active, and blood-brain barrier-permeable agonist of the subtype 3 of the frog skin peptide receptor (BRS-3). MK-7725 has a high affinity for the human BRS-3 (hBRS-3), with an IC50 of 3 nM, and its functional activity in the mouse-derived BRS-3 (mBRS-3) model with an EC50 of 22 nM (105% agonistic). MK-7725 significantly reduces the body weight of obese rats and obese dogs. MK-7725 can be used for the treatment of obesity.

For research use only. We do not sell to patients.

  • CAS No.: 1034152-93-6
  • Formula: C25H19F6N5O5S
  • Molecular Weight:615.50
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • MK-7725 Chemical Structure
  • MK-7725 Chemical Structure
    MK-7725 Chemical Structure
CAS No.: 1034152-93-6
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  • MK-7725 Chemical Structure
    MK-7725 Chemical Structure
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  • MK-7725