1 Result for "

gonad-stimulating substance

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "gonad-stimulating substance" in MCE Product Catalog:

1-Methyladenine
1-Methyladenine
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Cat. No.: HY-113306
CAS No.: 5142-22-3
Purity:  99.88%
Category:  

Human Gut Microbiota Metabolites Natural Products Other Diseases Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

1-Methyladenine is a gonad maturation-promoting regulator. 1-Methyladenine is produced in testes and ovarian follicle cells of starfish under the induction of gonad-stimulating substance (GSS). 1-Methyladenine promotes starfish oocyte maturation and spawning, and modifies bases that regulate DNA structure. 1-Methyladenine converts T-A base pairs in double-stranded DNA into non-disruptive T (anti)m1A (syn) Hoogsteen conformation. If this conformational base is not repaired in a timely manner, 1-Methyladenine transforms into cytotoxic DNA damage and blocks the replication process .
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