6 Results for "

human+IgE

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "human+IgE" in MCE Product Catalog:

Cat. No.: HY-P991651

Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology

MEDI4212 is a humanized IgG1λ monoclonal antibody inhibitor targeting IgE. MEDI4212 potently inhibits human IgE-mediated functional responses through its receptor FcεRI, such as calcium signaling, β-hexosaminidase release and phagocytosis. MEDI4212 prevents the binding of IgE to CD23 with an IC50 of 8 nM. MEDI4212 can be used severe asthma research .
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Cat. No.: HY-P991592
CAS No.: 2755114-30-6

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

UB-221 is a humanized IgG1 monoclonal antibody inhibitor targeting IgE. UB-221 significantly decreases IgE synthesis by stabilization of membrane-bound CD23 on B lymphocytes and inhibits FcԑRI-mediated basophil activation and degranulation. UB-221 reduces IgE level in cynomolgus macaques and human IgE (ε, κ)-transgenic (hIGHE-knockin) mice. UB-221 can be used for asthma and chronic spontaneous urticaria (CSU) research .
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Cat. No.: HY-P99319
CAS No.: 380610-22-0
Synonyms: TNX 901; Anti-Human IgE Fc Recombinant Antibody

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Talizumab (TNX 901) is an anti-IgE humanized IgG1 monoclonal antibody .
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Cat. No.: HY-P3746
CAS No.: 62087-72-3
Target:  

Peptides

Research Areas:  

Inflammation/Immunology

Pentigetide is a sythsis pepetide (Asp-Ser-Asp-Pro-Arg or D-S-D-P-R), also know as “HEPP” for “Human IgE Pentapeptide”. Pentigetide can not produce IgE inhibition in several different systems, due to the aspartic acids in HEPP changed into an asparagine .
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Cat. No.: HY-P87172

Host:  

Mouse

Application:  

WB, IHC-P, ELISA

Reactivity:  

Human

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Cat. No.: HY-P87172-HRP

Host:  

Mouse

Application:  

WB, IHC-P, ELISA

Reactivity:  

Human

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