15 Results for "

human GIP receptor

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "human GIP receptor" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P10138
CAS No.: 1884226-05-4
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Human GIP(3-30), amide is a high affinity antagonist of the human GIP receptor in vitro. Human GIP(3-30), amide has potential anti-obesity and anti-diabetic effects .
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3
3 Cited Publications
Cat. No.: HY-P10138A
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Human GIP(3-30), amide TFA is the TFA salt form of human GIP(3-30), amide (HY-P10138). Human GIP(3-30), amide TFA is a high affinity antagonist of the human GIP receptor in vitro. Human GIP(3-30), amide TFA has potential anti-obesity and anti-diabetic effects .
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Cat. No.: HY-164535
CAS No.: 2887445-76-1
Synonyms: AMG 133
Maridebart cafraglutide (AMG 133) is a long-acting peptide-antibody conjugate that combines GLP-1 receptor agonist with glucose-dependent insulinotropic polypeptide (GIP) receptor antagonism. Maridebart cafraglutide shows antagonist activity against human, cynomolgus monkey and rat GIPR with IC50 values of 46.4 nM, 26.5 nM, 822.3 nM, respectively. Maridebart cafraglutide shows agonist activity against human, cynomolgus monkey, rat and mouse GLP-1R with EC50 values of 24.4 pM, 5.7 pM, 2.4 pM and 123 pM, respectively. Maridebart cafraglutide can be used for the study of obesity and type 2 diabetes .
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Cat. No.: HY-P3247
CAS No.: 444073-04-5
Target:  

Insulin Receptor

[D-Ala2]-GIP (human) is a GIP receptor agonist (EC50 = 630 pM). [D-Ala2]-GIP (human) improves glucose tolerance. [D-Ala2]-GIP (human) shows neuroprotective activity in MPTP (HY-W114750)-induced Parkinson's disease model. [D-Ala2]-GIP (human) also improves cognitive function and hippocampal synaptic plasticity in obese diabetic rats. [D-Ala2]-GIP (human) can be used for research of type 2 diabetes, Parkinson's disease, etc
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Cat. No.: HY-P2542
CAS No.: 1802086-25-4
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

GIP (3-42), human acts as a glucose-dependent insulinotropic polypeptide (GIP) receptor antagonist, moderating the insulin secreting and metabolic actions of GIP in vivo .
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Cat. No.: HY-P3584A
Synonyms: (Pro3) Gastric Inhibitory Peptide, human TFA
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

(Pro3) GIP, human TFA is an efficacious, stable and specific human GIP receptor (hGIPR) full agonist. (Pro3) GIP, human TFA has high binding affinity for human GIPR with Ki/ Kd value of 0.90 nM. (Pro3) GIP, human TFA human can be used for the research of obesity-related diabetes .
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Cat. No.: HY-P3584
CAS No.: 299898-52-5
Synonyms: (Pro3) Gastric Inhibitory Peptide, human
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

(Pro3) GIP, human ((Pro3) Gastric Inhibitory Peptide, human) is an efficacious, stable and specific human GIP receptor (hGIPR) full agonist. (Pro3) GIP, human has high binding affinity for human GIPR with Ki/ Kd values of 0.90 nM. (Pro3) GIP, human can be used for the research of obesity-related diabetes .
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Cat. No.: HY-P0165B
CAS No.: 1022150-16-8
Synonyms: ITM077 acetate; R1583 acetate; BIM51077 acetate
Target:  

GLP Receptor

Research Areas:  

Metabolic Disease

Taspoglutide (R1583) acetate is an agonist of the glucagon-like peptide 1 receptor (GLP-1R) with an Ki value of 1.1 nM. Taspoglutide acetate induces cAMP accumulation in CHO-K1 cells expressing human GLP-1R (EC50 = 0.06 nM). Taspoglutide acetate decreases blood levels of glucose and increases blood levels of insulin in a glucose tolerance test in Zucker diabetic obese rats. Taspoglutide acetate reduces blood levels of gastric inhibitory polypeptide (GIP), plasma levels of triglycerides, and body weight in the same model .
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Cat. No.: HY-156073
CAS No.: 1998714-25-2
LY3325656 is a selective GPR142 receptor agonist. LY3325656 selectively activates GPR142 in humans and mice. LY3325656 enhances glucose-dependent insulin secretion, glucagon secretion, as well as the secretion of incretin hormones GLP-1 and GIP. LY3325656 can be used in research related to type 2 diabetes .
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Cat. No.: HY-P702285
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory Polypeptide receptor; PGQTL2; Glucose-Dependent Insulinotropic Polypeptide receptor
Species:  
Source:  
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Cat. No.: HY-P702800
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory Polypeptide receptor; PGQTL2; Glucose-Dependent Insulinotropic Polypeptide receptor
Species:  
Source:  
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Cat. No.: HY-P703990
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory Polypeptide receptor; PGQTL2; Glucose-Dependent Insulinotropic Polypeptide receptor
Species:  
Source:  
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Cat. No.: HY-P703982
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory Polypeptide receptor; PGQTL2; Glucose-Dependent Insulinotropic Polypeptide receptor
Species:  
Source:  
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Cat. No.: HY-171302
CAS No.: 2766799-78-2
Target:  

GLP Receptor

Research Areas:  

Metabolic Disease

GLP-1R/GIPR agonist-2 is a GIPR agonist. GLP-1R/GIPR agonist-2 potentiates GIP(1-42)-induced intracellular cAMP production in cells expressing human GIPR. GLP-1R/GIPR agonist-2 can be used for the research of type II diabetes mellitus .
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Cat. No.: HY-P7693
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C1QTNF1; Complement C1q Tumor Necrosis Factor-Related Protein 1; C1q And TNF Related 1; C1q And Tumor Necrosis Factor Related Protein 1; CTRP1; G Protein Coupled receptor Interacting Protein; GIP; G Protein-Coupled receptor-Interacting Protein; ZSIG37; FL
Species:  
Source:  
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