2. Protéines recombinantes
  3. Biotinylated Proteins
  4. GIPR Protein, Human (Biotinylated, HEK293, His, Avi)

GIPR Protein, Human (Biotinylated, HEK293, His, Avi)

Cat. No.: HY-P703982
Instruction de manipulation Technical Support

GIPR protein, a receptor for glucose-dependent insulinotropic polypeptide (GIP), operates through G proteins that activate adenylyl cyclase. Its capacity for homodimer and heterodimer formation with GLP1R implies potential interactions between receptors linked to incretin hormones. GIPR Protein, Human (Biotinylated, HEK293, His, Avi) is the recombinant human-derived GIPR protein, expressed by HEK293, with C-Avi and C-His labeled tag.

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Description

GIPR protein, a receptor for glucose-dependent insulinotropic polypeptide (GIP), operates through G proteins that activate adenylyl cyclase. Its capacity for homodimer and heterodimer formation with GLP1R implies potential interactions between receptors linked to incretin hormones. GIPR Protein, Human (Biotinylated, HEK293, His, Avi) is the recombinant human-derived GIPR protein, expressed by HEK293, with C-Avi and C-His labeled tag.
Background

The GIPR protein functions as a receptor for glucose-dependent insulinotropic polypeptide (GIP). Its activity is mediated by G proteins, specifically those that activate adenylyl cyclase. Notably, GIPR has the potential to form homodimers and heterodimers with GLP1R, suggesting a possible interaction between receptors associated with incretin hormones.
Species

Human
Source

HEK293
Tag

C-Avi;C-8*His
Accession

P48546-1 (G26-Q138)
Gene ID

2696
Molecular Construction
N-term
GIPR (G26-Q138)
Accession # P48546-1
8*His-Avi
C-term
Protein Length

Extracellular Domain
Conjugation

Biotin
Synonyms
GIP-R; GIPR; PGQTL2
AA Sequence

GSKGQTAGELYQRWERYRRECQETLAAAEPPSGLACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGLWRDHTQCENPEKNEAFLDQRLILERLQ

Predicted Molecular Mass
15.9 kDa
Masse moléculaire

Approximately 28-38 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Glycosylation
Yes
Pureté

≥ 95%, as determined by Bis-Tris PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Instruction de manipulation (2659 KB)

GIPR Protein, Human (Biotinylated, HEK293, His, Avi) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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GIPR Protein, Human (Biotinylated, HEK293, His, Avi)
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