65 Results for "

hydroxycitric-acid

" in MedChemExpress (MCE) Product Catalog:
Products (65)

65 Results for "hydroxycitric-acid" in MCE Product Catalog:

42
Liraglutide
Liraglutide
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42 Publications Verification
Referencia número: HY-P0014
No. CAS: 204656-20-2
Target:  

GCGR GLP Receptor

Áreas de investigación:  

Neurological Disease Metabolic Disease Inflammation/Immunology

Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus.
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42
Liraglutide TFA
Liraglutide TFA
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42 Publications Verification
Referencia número: HY-P0014B
Target:  

GLP Receptor

Áreas de investigación:  

Metabolic Disease

Liraglutide (TFA) is an agonist of glucagon-like peptide 1 receptor (GLP-1). Liraglutide (TFA) can activate GLP-1, leading to the release of insulin in the presence of increased glucose concentration. Liraglutide (TFA) also reduces glucagon secretion in a glucose-dependent manner. Liraglutide (TFA) can be studied in research on type 2 diabetes .
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16
Octreotide acetate
Octreotide acetate
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16 Cited Publications
Referencia número: HY-17365
No. CAS: 79517-01-4
Synonyms: SMS 201-995 acetate
Target:  

Somatostatin Receptor

Áreas de investigación:  

Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer

Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently.
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3
Cagrilintide
Cagrilintide
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3 Cited Publications
Referencia número: HY-P3462
No. CAS: 1415456-99-3
Target:  

CGRP Receptor

Áreas de investigación:  

Metabolic Disease

Cagrilintide is an investigational novel long-acting acylated amylin analogue, acts as nonselective amylin receptors (AMYR) and calcitonin G protein-coupled receptor (CTR) agonist. Cagrilintide induces significant weight loss and reduces food intake. Cagrilintide has the potential for the research of obesity .
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3
Cagrilintide acetate
Cagrilintide acetate
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3 Cited Publications
Referencia número: HY-P3462A
Target:  

CGRP Receptor

Áreas de investigación:  

Metabolic Disease

Cagrilintide acetate is a non-selective AMYR/CTR agonist and long-acting acylated amylase analogue. Cagrilintide acetate causes a reduction in food intake and significant weight loss in a dose-dependent manner. Cagrilintide acetate can be used in obesity studies .
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1
Cotadutide
Cotadutide
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1 Cited Publications
Referencia número: HY-P2231
No. CAS: 1686108-82-6
Synonyms: MEDI0382
Target:  

GCGR

Áreas de investigación:  

Metabolic Disease

Cotadutide (MEDI0382) is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC50 values of 6.9 pM and 10.2 pM, respectively. Cotadutide exhibits ability to facilitate both weight loss and glycaemic control, and alleviate fibrosis. Cotadutide can be used in the research of obesity and type 2 diabetes (T2D) .
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1
Cotadutide acetate
Cotadutide acetate
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1 Cited Publications
Referencia número: HY-P2231A
Synonyms: MEDI0382 acetate
Target:  

GCGR

Áreas de investigación:  

Metabolic Disease

Cotadutide (MEDI0382) acetate is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC50 values of 6.9 pM and 10.2 pM, respectively. Cotadutide acetate exhibits ability to facilitate both weight loss and glycaemic control, and alleviate fibrosis. Cotadutide acetate can be used in the research of obesity and type 2 diabetes (T2D) .
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1
Didemnin B
Didemnin B
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1 Cited Publications
Referencia número: HY-105055
No. CAS: 77327-05-0
Pureza:  99.95%
Category:  

Natural Products Animals Marine natural products Other marine organisms Disease Research Fields Cancer

Target:  

Others

Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .
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1
Dapiglutide
Dapiglutide
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1 Cited Publications
Referencia número: HY-P3291
No. CAS: 2296814-85-0
Synonyms: ZP7570
Target:  

GCGR

Áreas de investigación:  

Metabolic Disease

Dapiglutide (ZP7570) is a long-acting glucagon-like peptide-1 receptor 1R (GLP-1R)/Glucagon-like peptide-2 receptor (GLP-2R) dual agonist. Dapiglutide alleviates intestinal dysfunction in a mouse short bowel model and has anti-obesity effects .
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1
MANS peptide
MANS peptide
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1 Cited Publications
Referencia número: HY-P10218
No. CAS: 479482-23-0
Target:  

MARCKS PKC

Áreas de investigación:  

Inflammation/Immunology Cancer

MANS peptide is an inhibitor for myristoylated alanine-rich C kinase substrate (MARCKS), which competes with MARCKS in cells for membrane binding, and thus inhibits the stimulation of mucin secretion and tumor metastasis .
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1
MANS peptide TFA
MANS peptide TFA
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1 Cited Publications
Referencia número: HY-P10218A
Target:  

MARCKS PKC

Áreas de investigación:  

Inflammation/Immunology Cancer

MANS peptide TFA is the TFA salt form of MANS peptide (HY-P10218). MANS peptide TFA is an inhibitor for myristoylated alanine-rich C kinase substrate (MARCKS), which competes with MARCKS in cells for membrane binding, and thus inhibits the stimulation of mucin secretion and tumor metastasis .
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1
dCNP
dCNP
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1 Cited Publications
Referencia número: HY-P10869
Target:  

Natriuretic Peptide Receptor (NPR)

Áreas de investigación:  

Inflammation/Immunology Cancer

dCNP binds to NPR-B/C receptor, activates cGMP signaling pathway, and regulates vascular function. dCNP exhibits anti-hypoxia property through downregulation of hypoxia-related genes expressions like HIF1α and HIF2α. dCNP inhibits the induction of tumor stroma and exhibits anti-fibrosis activity. dCNP upregulates CTLs, NK cells, and conventional type 1 dendritic cells in tumors, and activates immune responses .
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β-Amanitin
β-Amanitin
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Referencia número: HY-125586
No. CAS: 21150-22-1
Pureza:  ≥96.0%
Target:  

DNA/RNA Synthesis ADC Payloads

Áreas de investigación:  

Cancer

β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs) .
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Rusfertide
Rusfertide
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Referencia número: HY-P10272
No. CAS: 1628323-80-7
Synonyms: PTG-300
Target:  

Ferroportin

Áreas de investigación:  

Others

Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis .
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Liraglutide-13C5,15N tetraTFA
Liraglutide-13C5,15N tetraTFA
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Referencia número: HY-P0014S1
Target:  

Isotope-Labeled Compounds GLP Receptor GCGR

Áreas de investigación:  

Others

Liraglutide- 13C6, 15 tetraTFA is the 13C and 15N labeled Liraglutide (HY-P0014) . Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used for the study of type 2 diabetes mellitus .
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RG7697
RG7697
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Referencia número: HY-P10271
Synonyms: NNC0090-2746; MAR709; RO6811135
Target:  

GLP Receptor

Áreas de investigación:  

Metabolic Disease

RG7697 is a dual agonist for glucagon-like peptide receptor (GLP Receptor) and glucosedependent insulinotropic polypeptide receptor (GIPR), with EC50 of 5 and 3 pM, respectively. RG7697 exhibits antihyperglycemic property .
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SAR441255
SAR441255
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Referencia número: HY-P10031
Target:  

GLP Receptor GCGR

Áreas de investigación:  

Metabolic Disease

SAR441255 is a GLP-1R/GCGR/GIPR agonist, with human EC50 values of 1.03 pM, 1.01 pM, and 0.73 pM, respectively. SAR441255 stimulates receptor activity and drives cAMP accumulation. SAR441255 can be used for the research of type 2 diabetes, obesity .
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BMSpep-57
BMSpep-57
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Referencia número: HY-P3143
No. CAS: 1629655-80-6
Target:  

PD-1/PD-L1

Áreas de investigación:  

Cancer

BMSpep-57 is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC50 of 7.68 nM. BMSpep-57 binds to PD-L1 with Kds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 facilitates T cell function by in creasing IL-2 production in PBMCs .
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Urcosimod
Urcosimod
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Referencia número: HY-P11273
No. CAS: 1610366-43-2
Synonyms: OK 101
Target:  

Chemerin Receptor

Áreas de investigación:  

Neurological Disease Inflammation/Immunology

Urcosimod (OK 101) is a lipid-coupled chemokine peptide, a ChemR23 G protein-coupled receptor agonist, which has been shown to have anti-inflammatory and analgesic activities. Urcosimod can be used for dry eye research .
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GIP/GLP-1 dual receptor agonist-1
GIP/GLP-1 dual receptor agonist-1
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Referencia número: HY-153476
No. CAS: 2807481-02-1
Target:  

GCGR GLP Receptor

Áreas de investigación:  

Inflammation/Immunology

GIP/GLP-1 dual receptor agonist-1 is a GIP/GLP-1 dual receptor agonist. GIP/GLP-1 dual receptor agonist-1 is used in the research of metabolic disorders and fatty liver diseases, including non-alcoholic steatohepatitis (NASH) and non-alcoholic fatty liver disease (NAFLD) .
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