29 Results for "

lipid utilization

" in MedChemExpress (MCE) Product Catalog:
Products (29)

29 Results for "lipid utilization" in MCE Product Catalog:

20
20 Cited Publications
Cat. No.: HY-145405
CAS No.: 1220890-25-4
Purity:  99.91%
C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-130751
CAS No.: 127512-29-2
Purity:  ≥98.0%
DODAP is a cationic lipid utilized as the lipid component in liposomes (pKa = 5.59 in TNS binding tests). DODAP is employed for encapsulating siRNA and delivering immunostimulated chemotherapeutic agents both in vitro and in vivo. DODAP holds great promise for research in vaccines and inflammation .
loading...
    loading...
Cat. No.: HY-148842
CAS No.: 2639634-80-1
Purity:  98.13%
Synonyms: C14-494
C14-4 is an ionizable lipid utilized for the synthesis of lipid nanoparticles (LNPs). C14-4 enhances mRNA delivery, enabling the effective transport of mRNA to primary human T cells, which in turn induces functional protein expression. C14-4 demonstrates high transfection efficiency while maintaining low cytotoxicity .
loading...
    loading...
Cat. No.: HY-N3686
CAS No.: 488-82-4
Target:  

AMPK PGC-1α

D-Arabitol is an orally active D-enantiomer of arabitol. D-Arabitol modulates the composition of gut microbiota, increases short-chain fatty acids, and promotes AMPK-PGC-1α-related browning of white adipose tissue. D-Arabitol improves weight gain, fat accumulation, insulin resistance, lipid deposition and inflammatory responses. D-Arabitol serves as the sole carbon/energy source for Bacillus methanolicus MGA3, a strain that can co-utilize it with mannitol. D-Arabitol is applicable to obesity-related research .
loading...
    loading...
Cat. No.: HY-P2752
CAS No.: 9004-02-8
Synonyms: LPL
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease Cancer

Lipoprotein lipase, Pseudomonas sp (LPL) is a multifunctional enzyme from adipose tissue, heart and skeletal muscle, islets and macrophages. Lipoprotein lipase promotes normal lipoprotein metabolism, delivery and utilization of tissue-specific substrates. Lipoprotein lipase catalyzes the rate-limiting step of lipids in blood circulation .
loading...
    loading...
Cat. No.: HY-P10471A
Synonyms: MARCKS-ED TFA
Target:  

MARCKS PKC

Research Areas:  

Others

MPSD TFA (MARCKS-ED TFA) is the TFA salt form of MPSD (HY-P10471). MPSD TFA is a 25-amino acid peptide based on the effector domain sequence of the intracellular membrane protein myristoylated alanine-rich C-kinase substrate (MARCKS). MPSD TFA can sense membrane curvature and recognize phosphatidylserine. MPSD TFA can be utilized as biological probe to study membrane shape and lipid composition .
loading...
    loading...
Cat. No.: HY-N3686R
CAS No.: 488-82-4
D-Arabitol (Standard) is the analytical standard of D-Arabitol. This product is intended for research and analytical applications. D-Arabitol is an orally active D-enantiomer of arabitol. D-Arabitol modulates the composition of gut microbiota, increases short-chain fatty acids, and promotes AMPK-PGC-1α-related browning of white adipose tissue. D-Arabitol improves weight gain, fat accumulation, insulin resistance, lipid deposition and inflammatory responses. D-Arabitol serves as the sole carbon/energy source for Bacillus methanolicus MGA3, a strain that can co-utilize it with mannitol. D-Arabitol is applicable to obesity-related research.
loading...
    loading...
Cat. No.: HY-N15841
CAS No.: 67492-18-6
Category:  

Lipids

Target:  

Ceramidase

C25 Ceramide (d18:1/25:0) is an endogenous ultra-long-chain ceramide that antagonizes the detrimental effects of long-chain ceramides on insulin sensitivity. C25 Ceramide (d18:1/25:0) is specifically enriched in oxidative skeletal muscle fibers, where it serves dual roles in providing structural support to cell membranes and regulating cellular signaling. By participating in the regulation of lipid homeostasis within muscle fibers, C25 Ceramide (d18:1/25:0) helps maintain normal insulin signaling. C25 Ceramide (d18:1/25:0) is primarily utilized in research concerning metabolic diseases—particularly in mechanistic studies investigating the muscle fiber type-specific aspects of insulin resistance .
loading...
    loading...
Cat. No.: HY-P11153
HGH fragment 176-191 is a fragment of Human Growth Hormone. HGH fragment 176-191 binds with high affinity to Ki-67, MiB proteins, and estrogen receptors. HGH fragment 176-191 enhances the toxicity of chitosan nanoparticles loaded with Doxorubicin (HY-15142A) against breast cancer. HGH fragment 176-191 promotes lipolysis and fat utilization in mice. HGH fragment 176-191 can be used in research related to targeted drug delivery for cancer and lipid metabolism .
loading...
    loading...
Cat. No.: HY-P10471
CAS No.: 134248-85-4
Synonyms: MARCKS-ED
Target:  

MARCKS PKC

Research Areas:  

Others

MPSD (MARCKS-ED) is a 25-amino acid peptide based on the effector domain sequence of the intracellular membrane protein myristoylated alanine-rich C-kinase substrate (MARCKS). MPSD can sense membrane curvature and recognize phosphatidylserine. MPSD can be utilized as biological probe to study membrane shape and lipid composition .
loading...
    loading...
Cat. No.: HY-P10471D
CAS No.: 190711-66-1
Synonyms: MARCKS-ED control peptide
Target:  

MARCKS PKC

Research Areas:  

Others

MPSD control peptide (MARCKS-ED control peptide) is a control peptide for MPSD peptide (HY-P10471). MPSD (MARCKS-ED) is a 25-amino acid peptide based on the effector domain sequence of the intracellular membrane protein myristoylated alanine-rich C-kinase substrate (MARCKS). MPSD can sense membrane curvature and recognize phosphatidylserine. MPSD can be utilized as biological probe to study membrane shape and lipid composition .
loading...
    loading...
Cat. No.: HY-140739A
CAS No.: 185844-12-6
Target:  

Liposome

Research Areas:  

Neurological Disease Cancer

DSPE-PEG2000-Maleimide free acid is a phospholipid-PEG conjugate. DSPE-PEG2000-Maleimide free acid utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles. DSPE-PEG2000-Maleimide free acid covalently couples to the sulfhydryl (-SH) of ligands (such as antibodies, peptides, or proteins) via thiol-maleimide click chemistry, giving the particles targeting capabilities. DSPE-PEG2000-Maleimide free acid can be used in the researches of breast cancer, lymphoma, and inherited retinal degeneration .
loading...
    loading...
Cat. No.: HY-148178
CAS No.: 2260904-47-8
Purity:  99.50%
Target:  

Parasite

Research Areas:  

Infection

MMV688533 is an antimalarial agent. MMV688533 interferes with intracellular trafficking, lipid utilization, and endocytosis pathways in Plasmodium falciparum. MMV688533 rapidly kills asexual blood-stage Plasmodium falciparum and Plasmodium vivax parasites in vitro and reduces parasitemia in a Plasmodium falciparum NSG mouse model. MMV688533 can be used for the research of malaria .
loading...
    loading...
Cat. No.: HY-168775
CAS No.: 2921586-67-4
Research Areas:  

Others

Lipid 29d is an unsaturated ionizable cationic lipid that can be utilized in the formation of lipid nanoparticles and the delivery of mRNA .
loading...
    loading...
Cat. No.: HY-158867
CAS No.: 913194-16-8
Target:  

Liposome

Research Areas:  

Infection

DOSPA hydrochlorid is a frequently utilized cationic lipid in the generation of Lipid Nanoparticles (LNPs) for the development of mRNA vaccines, including the COVID-19 vaccine.
loading...
    loading...
Cat. No.: HY-171019
CAS No.: 2953044-98-7
Target:  

Liposome

Research Areas:  

Others

Lipid 119-23 is an ionizable cationic lipid which can be utilized in the formation of lipid nanoparticles and the delivery of mRNA. Lipid 119-23 exhibits an enhanced capability to express functional mCre in several categories of immune cells, spanning the liver, spleen and lung .
loading...
    loading...
Cat. No.: HY-168776
CAS No.: 1226552-44-8
Research Areas:  

Others

(S)-C12-200 is the (S)-isomer of C12-200 (HY-145405), an ionizable cationic lipid and helper lipid. (S)-C12-200 can be utilized in the formation of lipid nanoparticles and mRNA delivery .
loading...
    loading...
Cat. No.: HY-179677
DSPE-PEG2000-Mal-Cys-DT7 is a phospholipid-PEG conjugate. DSPE-PEG2000-Mal-Cys-DT7 utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles.
loading...
    loading...
Cat. No.: HY-179677A
DSPE-PEG3400-Mal-Cys-DT7 is a phospholipid-PEG conjugate. DSPE-PEG3400-Mal-Cys-DT7 utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles.
loading...
    loading...
Cat. No.: HY-159483
CAS No.: 2674058-66-1
Research Areas:  

Cancer

SelB-1 serves as a dual inhibitor for Topoisomerase I/II. SelB-1 possesses anticancer activity and can be utilized in the research of prostate cancer and colon cancer. Furthermore, SelB-1 is also capable of inducing autophagy gene expression and lipid peroxidation, while simultaneously reducing the level of GSH .
loading...
    loading...