488-82-4
Chemical Structure
D-Arabitol
- CAS No.: 488-82-4
- Formula:C5H12O5
- Molecular Weight:152.15
IUPAC Name: pentane-1,2,3,4,5-pentaol
InChIKey: HEBKCHPVOIAQTA-UHFFFAOYSA-N
SMILES: OCC(O)C(O)C(O)CO
Biological Activity: D-Arabitol is an orally active D-enantiomer of arabitol. D-Arabitol modulates the composition of gut microbiota, increases short-chain fatty acids, and promotes AMPK-PGC-1α-related browning of white adipose tissue. D-Arabitol improves weight gain, fat accumulation, insulin resistance, lipid deposition and inflammatory responses. D-Arabitol serves as the sole carbon/energy source for Bacillus methanolicus MGA3, a strain that can co-utilize it with mannitol. D-Arabitol is applicable to obesity-related research[1][2].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
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D-Arabitol | 99.92% | D-Arabitol is an orally active D-enantiomer of arabitol. D-Arabitol modulates the composition of gut microbiota, increases short-chain fatty acids, and promotes AMPK-PGC-1α-related browning of white adipose tissue. D-Arabitol improves weight gain, fat accumulation, insulin resistance, lipid deposition and inflammatory responses. D-Arabitol serves as the sole carbon/energy source for Bacillus methanolicus MGA3, a strain that can co-utilize it with mannitol. D-Arabitol is applicable to obesity-related research. | ||||||||||||||||||||
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D-Arabitol (Standard) | 99.92% | D-Arabitol (Standard) is the analytical standard of D-Arabitol (HY-N3686). This product is intended for research and analytical applications. D-Arabitol is an orally active D-enantiomer of arabitol. D-Arabitol modulates the composition of gut microbiota, increases short-chain fatty acids, and promotes AMPK-PGC-1α-related browning of white adipose tissue. D-Arabitol improves weight gain, fat accumulation, insulin resistance, lipid deposition and inflammatory responses. D-Arabitol serves as the sole carbon/energy source for Bacillus methanolicus MGA3, a strain that can co-utilize it with mannitol. D-Arabitol is applicable to obesity-related research. | ||||||||||||||||||||
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D-Arabitol-13C-1 | D-Arabitol-13C-1 is the 13C labeled D-Arabitol. D-Arabitol is an orally active D-enantiomer of arabitol. D-Arabitol modulates the composition of gut microbiota, increases short-chain fatty acids, and promotes AMPK-PGC-1α-related browning of white adipose tissue. D-Arabitol improves weight gain, fat accumulation, insulin resistance, lipid deposition and inflammatory responses. D-Arabitol serves as the sole carbon/energy source for Bacillus methanolicus MGA3, a strain that can co-utilize it with mannitol. D-Arabitol is applicable to obesity-related research. | |||||||||||||||||||||
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D-Arabitol-d7 | D-Arabitol-d7 is the deuterium labeled D-Arabitol (HY-N3686). D-Arabitol is a polyol and its accumulation may cause a neurotoxic effect in human. | |||||||||||||||||||||
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D-Arabitol-13C | D-Arabitol-13C is the 13C labeled D-Arabitol. D-Arabitol is an orally active D-enantiomer of arabitol. D-Arabitol modulates the composition of gut microbiota, increases short-chain fatty acids, and promotes AMPK-PGC-1α-related browning of white adipose tissue. D-Arabitol improves weight gain, fat accumulation, insulin resistance, lipid deposition and inflammatory responses. D-Arabitol serves as the sole carbon/energy source for Bacillus methanolicus MGA3, a strain that can co-utilize it with mannitol. D-Arabitol is applicable to obesity-related research. | |||||||||||||||||||||
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D-Arabitol-13C-2 | D-Arabitol-13C-2 is the 13C labeled D-Arabitol. D-Arabitol is an orally active D-enantiomer of arabitol. D-Arabitol modulates the composition of gut microbiota, increases short-chain fatty acids, and promotes AMPK-PGC-1α-related browning of white adipose tissue. D-Arabitol improves weight gain, fat accumulation, insulin resistance, lipid deposition and inflammatory responses. D-Arabitol serves as the sole carbon/energy source for Bacillus methanolicus MGA3, a strain that can co-utilize it with mannitol. D-Arabitol is applicable to obesity-related research. | |||||||||||||||||||||
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Ribitol | 99.93% | Ribitol is a crystalline pentose alcohol formed by the reduction of ribose. Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol. | ||||||||||||||||||||
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D-Sorbitol-13C6 | 99.94% | D-Sorbitol-13C6 is the 13C labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement. | ||||||||||||||||||||
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D-Mannitol-13C | 99.9% | D-Mannitol-13C is the 13C labeled D-Mannitol (HY-N0378). D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells. D-Mannitol is commonly used to maintain osmotic pressure between the plant cytoplasm and the culture medium and protect cells when the cell wall is weakened or even removed. | ||||||||||||||||||||
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D-Mannitol-13C6 | 99.93% | D-Mannitol-13C6 is the 13C labeled D-Mannitol (HY-N0378). D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells. D-Mannitol is commonly used to maintain osmotic pressure between the plant cytoplasm and the culture medium and protect cells when the cell wall is weakened or even removed. | ||||||||||||||||||||
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Xylitol (Standard) | 98.94% | Xylitol (Standard) is the analytical standard of Xylitol. This product is intended for research and analytical applications. Xylitol can be classified as polyols and sugar alcohols. | ||||||||||||||||||||
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DL-Arabitol | DL-Arabitol is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | |||||||||||||||||||||
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DL-Mannitol-13C | DL-Mannitol-13C is the 13C-labeled DL-Mannitol. DL-Mannitol is obtained by combining D-mannitol with a sample of Lmannitol obtained by reduction of L-mannono-1, Clactone. | |||||||||||||||||||||
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L-Arabinitol (Standard) | 99.95% | L-Arabinitol (Standard) is the analytical standard of L-Arabinitol. This product is intended for research and analytical applications. L-Arabinitol is a potential biomarker for the comsuption of the food products such as sweet potato, deerberry, moth bean, and is also associated with Alzheimer's disease and ribose-5-phosphate isomerase deficiency. | ||||||||||||||||||||
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D-Iditol | 98.0% | D-Iditol is a fungal metabolite, a sugar alcohol that accumulates in galactokinase deficiency. D-Iditol may have potential antitumour activity. | ||||||||||||||||||||
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Dulcite-13C | Dulcite-13C is the 13C labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact. | |||||||||||||||||||||
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References
- [1]. Li X, et al. d-Arabitol Ameliorates Obesity and Metabolic Disorders via the Gut Microbiota-SCFAs-WAT Browning Axis. J Agric Food Chem. 2023;71(1):522-534. [Content Brief]
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[2]. López MG, et al. Characterization of D-Arabitol as Newly Discovered Carbon Source of Bacillus methanolicus. Front Microbiol. 2019 Jul 31;10:1725.
[Content Brief]