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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
mCMV
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "mCMV" in MCE Product Catalog:
Cat. No.: HY-148852
CAS No.: 282536-25-8
PNU-183792, a 4-oxo-dihydroquinoline, is an orally active HSV polymerases inhibitor. PNU-183792 shows a broad-spectrum antiviral activity, with IC50 values of 0.69 μM, 0.37 μM and 0.58 μM for human cytomegalovirus (HCM), varicella zoster virus and HSV polymerases, respectively. PNU-183792 is inactive against human α, γ and δ polymerases. PNU-183792 also inhibits simian varicella virus (SVV), murine cytomegalovirus (MCMV) and rat cytomegalovirus (RCMV) .
Cat. No.: HY-16721
CAS No.: 632325-71-4
Synonyms: Filociclovir; ZSM-I-62; MBX-400
Cyclopropavir (Filociclovir) is an orally active and broad-spectrum anti-herpesvirus compound. Cyclopropavir inhibits UL97 kinase activity. Cyclopropavir has antiviral activity against HCMV, MCMV, and HAdV6 viruses .
Synonyms: BAY 38-4766
Tomeglovir is a potent anti-CMV agent, inhibiting processing of viral DNA-concatemers, with IC50s of 0.34 μM and 0.039 μM for HCMV and MCMV.
PMEDAP is a potent inhibitor of human immunodeficiency virus (HIV) replication. PMEDAP has anti-murine cytomegalovirus (MCMV) activity. PMEDAP is a very potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality .
Cat. No.: HY-P990276
Target:
Research Areas:
Cat. No.: HY-P10509
CAS No.: 127902-44-7
Cat. No.: HY-183419
CAS No.: 824431-12-1
Synonyms: RGB-315389
AX-7396 (RGB-315389) is a pUL97 protein kinase inhibitor with an IC50 of 0.35 μM against HCMV pUL97 kinase. AX-7396 inhibits the replication of wild-type and agent-resistant HCMV, GPCMV, MCMV and RCMV in vitro, with the strongest potency against MCMV (IC50 1.6 μM). AX-7396 shows no significant antiviral activity in a mouse cytomegalovirus infection model. AX-7396 can be used in studies related to cytomegalovirus infection .
Cat. No.: HY-108261R
CAS No.: 233254-24-5
Synonyms: BAY 38-4766 (Standard)
Target:
Research Areas:
Tomeglovir (Standard) is the analytical standard of Tomeglovir (HY-108261). This product is intended for research and analytical applications. Tomeglovir is a potent anti-CMV agent, inhibiting processing of viral DNA-concatemers, with IC50s of 0.34 μM and 0.039 μM for HCMV and MCMV.
Cat. No.: HY-106382R
CAS No.: 113852-41-8
Target:
PMEDAP (Standard) is the analytical standard of PMEDAP (HY-106382). This product is intended for research and analytical applications. PMEDAP is a potent inhibitor of human immunodeficiency virus (HIV) replication. PMEDAP has anti-murine cytomegalovirus (MCMV) activity. PMEDAP is a very potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality .
Cat. No.: HY-137889
CAS No.: 347337-33-1
MLS8969 is a selective human cytomegalovirus (HCMV) entry inhibitor with an EC50 of 0.12 μM (HFFs). MLS8969 reduces viral protein levels and inhibits nuclear staining of HCMV pp65. MLS8969 can be used in studies related to human cytomegalovirus infection .
Cat. No.: HY-185150
CAS No.: 114088-58-3
Synonyms: 9-(2-Phosphonylmethoxy)ethylguanine
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Research Areas:
PMEG is a nuclear DNA polymerases α, δ, and ε inhibitor that causes DNA chain termination, inhibits DNA synthesis, induces cytotoxicity in dividing cells. PMEG is an acyclic nucleotide phosphonate that forms an active phosphorylated metabolite, PMEG diphosphate, within cells. PMEG has activity against leukemia and melanoma in rodent models. PMEG has poor cell permeability; its prodrug is Rabacfosadine (GS-9219) (HY-13640). PMEG shows antiviral activity against against various DNA virus infections including murine cytomegalovirus (MCMV) and human cytomegalovirus (HCMV). PMEG can be used for the research of non-hodgkin's lymphoma [1][2].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
