1. Anti-infection
  2. HIV
    CMV
  3. PMEDAP

PMEDAP 

Cat. No.: HY-106382
Handling Instructions

PMEDAP is a potent inhibitor of human immunodeficiency virus (HIV) replication. PMEDAP has anti-murine cytomegalovirus (MCMV) activity. PMEDAP is a very potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality.

For research use only. We do not sell to patients.

PMEDAP Chemical Structure

PMEDAP Chemical Structure

CAS No. : 113852-41-8

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Description

PMEDAP is a potent inhibitor of human immunodeficiency virus (HIV) replication. PMEDAP has anti-murine cytomegalovirus (MCMV) activity. PMEDAP is a very potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality[1][2].

In Vivo

PMEDAP (0.25-5 mg/kg; IP; daily; starting on the day of MSV-infected and continuing for an additional four days) causes a dose-dependent suppression of tumor formation and mortality in newborn mice inoculated with MSV[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Three-week-old male NMRI mice[1]
Dosage: 0.25 mg/kg, 1 mg/kg, 5 mg/kg
Administration: IP; daily; starting on the day of infection and continuing for an additional four days
Result: Effected a significant delay in tumor appearance and an enhancement of the survival rate of tumor-bearing mice.
Molecular Weight

288.20

Formula

C₈H₁₃N₆O₄P

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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PMEDAP
Cat. No.:
HY-106382
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