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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
mGluR8
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "mGluR8" in MCE Product Catalog:
3
3 Cited Publications
Synonyms: L-Serine O-phosphate; L-SOP
Category:
Human Gut Microbiota Metabolites Microorganisms Immune System Disorder Ketones, Aldehydes, Acids Disease markers Endogenous metabolite
Target:
2
Target:
2
2 Cited Publications
Cat. No.: HY-W017230
CAS No.: 207121-48-0
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1
1 Cited Publications
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AZ 12216052 is a mGluR8 positive allosteric modulator, and helps mGluR8 modulate signaling inputing to retinal ganglion cells. AZ 12216052 exhibits antianxiety effect .
Synonyms: ML396
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VU0422288 (ML396) is a positive allosteric modulator of group III mGluRs. VU0422288 inhibits mGluRs with EC50s of 125 nM, 146 nM, and 108 nM for mGluR4, mGluR7, and mGluR8, respectively in calcium mobilization assays. VU0422288 reverses deficits in contextual fear memory, social recognition, and apneas in Rett syndrome (RTT) model mice .
Synonyms: (S)-3,4-Dicarboxyphenylglycine
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(S)-3,4-DCPG is a selective agonist of metabotropic glutamate receptor 8a (mGluR8a) with an EC50 of 31 nM in AV12-664 cells expressing human mGluR8 .
Synonyms: L-Serine O-phosphate-13C3,15N; L-SOP-13C3,15N
Research Areas:
O-Phospho-L-serine (Standard) (L-Serine O-phosphate (Standard)) is the analytical standard of O-Phospho-L-serine (HY-15129). This product is intended for research and analytical applications. O-Phospho-L-serine is the immediate precursor to L-cystein in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8). O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2.
Cat. No.: HY-W017230R
CAS No.: 207121-48-0
Category:
Cat. No.: HY-100804R
CAS No.: 1115-65-7
Cat. No.: HY-W751156
CAS No.: 2734707-32-3
Synonyms: L-Serine O-phosphate-13C3; L-SOP-13C3
Cat. No.: HY-RS05840
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GRM8 Human Pre-designed siRNA Set A contains three designed siRNAs for GRM8 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS05842
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Grm8 Rat Pre-designed siRNA Set A contains three designed siRNAs for Grm8 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS05841
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Grm8 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Grm8 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
