GRM8 Antibody (YA3484)
(Synonyms: GLUR8; mGlu8; GPRC1H; MGLUR8)Based on 1 publication(s) in Google Scholar
GRM8 Antibody (YA3484) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GRM8.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
Publications Citing Use of MedChemExpress (MCE) GRM8 Antibody (YA3484)
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Applications
| Application |
WB
WB: Western Blot
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FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:200-1:400 | 1:10000 |
Product Details
GRM8 Antibody (YA3484) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GRM8.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 102 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 102 kDa
Purified recombinant fragment of human GRM8 (AA: extra 440-583) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Publications (1)
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Journal Impact Factor
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Most Recent
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Cancers (Basel)
Effects of Combining Immune-Priming Sub-Lethal Low-Dose Radiation with 4-1BB Activation and Gal-3 Blockade in In Vitro and Preclinical Group-3 Medulloblastoma Models. [Abstract]2026 Jun 10;18(12):1890. PMID: 42352424
Background
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Function
GRM8 is a G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity
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Subcellular Localization
Cell membrane; Multi-pass membrane protein
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Isoforms & Post-Translational Modification
O00222 has 3 isomers: O00222-1: 101741 Da (predicted); O00222-2: 101608 Da (predicted); O00222-3: 55948 Da (predicted).
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Subunit
Interacts with PICK1
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SwissProt ID
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Synonyms
GLUR8; mGlu8; GPRC1H; MGLUR8
Documentation
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