(S)-3,4-DCPG
Based on 1 Customer Validation
(S)-3,4-DCPG is a selective agonist of metabotropic glutamate receptor 8a (mGluR8a) with an EC50 of 31 nM in AV12-664 cells expressing human mGluR8.
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 201730-11-2
- Formula: C10H9NO6
- Molecular Weight:239.18
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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hmGluR8a 31 nM (EC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
<100 μM
Compound: 10
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Stimulation of [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells; Active
Stimulation of [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells; Active
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[PMID: 15801843] |
| HEK293 | EC50 |
8.8 μM
Compound: 10
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Stimulation od [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells
Stimulation od [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells
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[PMID: 15801843] |
Chemical Information
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CAS No. 201730-11-2
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Appearance Solid
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Molecular Weight 239.18
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Formula C10H9NO6
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Color White to light yellow
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SMILES
OC(C1=C(C=CC([C@H](N)C(O)=O)=C1)C(O)=O)=O
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Synonyms
(S)-3,4-Dicarboxyphenylglycine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 20 mg/mL (83.62 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.1810 mL | 20.9048 mL | 41.8095 mL | 104.5238 mL |
| 5 mM | 0.8362 mL | 4.1810 mL | 8.3619 mL | 20.9048 mL | |
| 10 mM | 0.4181 mL | 2.0905 mL | 4.1810 mL | 10.4524 mL | |
| 15 mM | 0.2787 mL | 1.3937 mL | 2.7873 mL | 6.9683 mL | |
| 20 mM | 0.2090 mL | 1.0452 mL | 2.0905 mL | 5.2262 mL | |
| 25 mM | 0.1672 mL | 0.8362 mL | 1.6724 mL | 4.1810 mL | |
| 30 mM | 0.1394 mL | 0.6968 mL | 1.3937 mL | 3.4841 mL | |
| 40 mM | 0.1045 mL | 0.5226 mL | 1.0452 mL | 2.6131 mL | |
| 50 mM | 0.0836 mL | 0.4181 mL | 0.8362 mL | 2.0905 mL | |
| 60 mM | 0.0697 mL | 0.3484 mL | 0.6968 mL | 1.7421 mL | |
| 80 mM | 0.0523 mL | 0.2613 mL | 0.5226 mL | 1.3065 mL |
(S)-3,4-DCPG Related Classifications
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