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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
methotrexate metabolite
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "methotrexate metabolite" in MCE Product Catalog:
1
Research Areas:
Methotrexate metabolite (DAMPA) is an active metabolite of Methotrexate. Methotrexate is a Folic acid (HY-16637) antagonist, widely used as an immunosuppressant. Methotrexate metabolite is an antimalarial agent that inhibits parasite growth under physiological folic acid conditions, with IC50 values of 446 nM and 812 nM against folic acid-sensitive strains and highly resistant strains, respectively. Methotrexate metabolite exhibits pharmacokinetic characteristics of rapid clearance and extensive metabolism, with a mean clearance rate of 1.9 l/kg/h and a mean terminal half-life of 51 minutes. Methotrexate metabolite is promising for research in the field of inflammation .
Target:
Research Areas:
7-Hydroxymethotrexate is a major metabolite of Methotrexate (HY-14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis .
Cat. No.: HY-108251R
CAS No.: 19741-14-1
Synonyms: DAMPA (Standard)
Research Areas:
Methotrexate metabolite (Standard) is the analytical standard of Methotrexate metabolite. This product is intended for research and analytical applications. Methotrexate metabolite (DAMPA), the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist that is widely used as an immunosuppressant and chemotherapeutic agent .
Cat. No.: HY-108251S
CAS No.: 1794780-00-9
Synonyms: DAMPA-d3
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Research Areas:
7-Hydroxydichloromethotrexate is a methotrexate metabolite which can be isolated from the urine of rabbits .
Cat. No.: HY-W654227
Cat. No.: HY-130569S
Cat. No.: HY-130569S1
CAS No.: 432545-62-5
Cat. No.: HY-130569S2
Cat. No.: HY-130569A
Target:
Research Areas:
7-Hydroxymethotrexate sodium is a major metabolite of Methotrexate (HY-14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis .
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Protocols
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