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mosquito larvae

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amyloid-β (2) Bacterial (2) Biochemical Assay Reagents (1) Cholinesterase (ChE) (3) Dihydroorotate Dehydrogenase (2) Environmental Pollutants (1) ERK (1) Ferroptosis (2) GABA Receptor (1) Glutathione Peroxidase (2) Heme Oxygenase (HO) (2) Insecticide (7) Keap1-Nrf2 (2) nAChR (2) NF-κB (2) PAI-1 (2) Parasite (3) Proton Pump (2) Reference Standards (1) Sodium Channel (1) Thrombin (2) Toll-like Receptor (TLR) (2) TRP Channel (2)
By Research Areas:	Cancer (2) Cardiovascular Disease (2) Infection (9) Inflammation/Immunology (2) Neurological Disease (3)

By Targets:

Amyloid-β (2)

Bacterial (2)

Biochemical Assay Reagents (1)

Cholinesterase (ChE) (3)

Dihydroorotate Dehydrogenase (2)

Environmental Pollutants (1)

ERK (1)

Ferroptosis (2)

GABA Receptor (1)

Glutathione Peroxidase (2)

Heme Oxygenase (HO) (2)

Insecticide (7)

Keap1-Nrf2 (2)

nAChR (2)

NF-κB (2)

PAI-1 (2)

Parasite (3)

Proton Pump (2)

Reference Standards (1)

Sodium Channel (1)

Thrombin (2)

Toll-like Receptor (TLR) (2)

TRP Channel (2)

By Research Areas:

Cancer (2)

Cardiovascular Disease (2)

Infection (9)

Inflammation/Immunology (2)

Neurological Disease (3)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y0261A

Ammonium sulphate,≥99.0%,AR	Environmental Pollutants Biochemical Assay Reagents	Others
Ammonium sulphate,≥99.0%,AR is an inorganic sulfate salt used for molecular biology . Ammonium sulphate,≥99.0%,AR can be used to precipitate proteins, separate antibodies, and enhance antigen-antibody reactions. Ammonium sulphate,≥99.0%,AR can serve as a nitrogen source in plant fertilizers and has developmentally toxicity to freshwater snails, but increases the number of Anopheles africanus and Culex mosquito larvae in rice paddies. Ammonium sulphate,≥99.0%,AR also inhibits the conversion of glucose to ascorbic acid in plants .

HY-N3097

Pellitorine	TRP Channel Amyloid-β Toll-like Receptor (TLR) Keap1-Nrf2 Heme Oxygenase (HO) Dihydroorotate Dehydrogenase Ferroptosis PAI-1 NF-κB ERK Proton Pump Glutathione Peroxidase Thrombin Insecticide Bacterial	Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Pellitorine is a bioactive natural amide compound. Pellitorine can competitively antagonize the activation of TRPV1 by Capsaicin (HY-10448), thereby reducing pain signal transmission. Pellitorine improves cognitive dysfunction by upregulating the BDNF-ERK1/2-CREB and Nrf2-HO-1 pathways. Pellitorine exerts anti-inflammatory and anti-sepsis effects by inhibiting the release of high mobility group protein B1 (HMGB1) and the expression of RAGE/TLR4. Pellitorine exerts its antithrombotic effect by prolonging the clotting time, inhibiting the activity of clotting factors and thrombin. Pellitorine inhibits lipid peroxidation and resists ferroptosis by upregulating GPX4 and DHODH. Pellitorine kills Aedes aegypti mosquito larvae by inhibiting V-type H⁺-ATPase and aquaporin 4 (AaAQP4). Pellitorine exhibits anti-cancer activity (e.g., leukemia and breast cancer) and has inhibitory effects on certain bacteria .

HY-N16433

Nodulisporic acid A	Parasite Insecticide	Infection
Nodulisporic acid A (Compound 1a) is an insecticidal agent. Nodulisporic acid A can isolated from fermentations of Nodulisporium sp. Nodulisporic acid A has a potent insecticidal activity against the larvae of the blowfly and mosquito with LC₅₀s of 0.5 and 0.3 ppm against A. aegypti and L. seracata, respectively. Nodulisporic acid A can be used for the development of insecticide .

HY-N8585

Neoprocurcumenol	Parasite	Infection
Neoprocurcumenol is a larvicidal compound that exerts significant toxicity on mosquito larvae with LC₅₀ and LC ₉₀ values of 13.69 and 23.92 ppm, respectively .

HY-N8914

Isoshinanolone	Others	Others
Isoshinanolone is a natural product that can be extracted from Plumbago capensis. Isoshinanolone has mosquito larvicidal activity against fourth instar larvae of A. aegypti, with an IC₅₀ value of 1.26 μg/mL .

HY-175607

AChE/nAChR-IN-1	Cholinesterase (ChE) nAChR	Infection Neurological Disease
AChE/nAChR-IN-1 (Compound 1a) is dual-functional inhibitor of AChE and nAChR. AChE/nAChR-IN-1 has potent toxicity and larvicidal effectiveness against Culex pipiens larvae with a LC₅₀ of 4 ng/mL. AChE/nAChR-IN-1 can be used as larvicides for mosquito-borne diseases research .

HY-N2976

Cabraleadiol monoacetate Betulafolianediol 3-acetate; Cabraleadiol 3-acetate	Others	Infection
Cabraleadiol monoacetate is a compound isolated from the lichen Pyxine consocians Vainio. Cabraleadiol monoacetate shows mosquito larvicidal activity against the second instar larvae of Aedes aegypti .

HY-159148

AChE-IN-70	Cholinesterase (ChE)	Others
AChE-IN-70 (compound 4) is a AChE inhibitor. AChE-IN-70 shows larvicidal activity against mosquito larvae (Culex pipiens L.). and can be used for study of mosquito control .

HY-118077

RE 11775	Others	Others
RE 11775 (m-tert-butylphenyl-N-methyl-N-(phenylthio) carbonate) is a new carbonate ester with unusually high toxicity to mosquito larvae. Laboratory and field evaluations have shown that it has potential for use in controlling sensitive and organophosphate-resistant larval and adult stages of Aedes nigromaculis (Ludlow). Preliminary studies also suggest that RE 11775 may also be useful for controlling sensitive and organophosphate-resistant Culex spccies. This new carbonate ester is relatively safe, with no adverse effects found in current testing.

HY-173413

Insecticidal agent 21	Insecticide Cholinesterase (ChE) nAChR Sodium Channel GABA Receptor	Others
Insecticidal agent 21 (Compound 6) is an insecticide that is effective against *Culex pipiens* larvae (LC₅₀: 0.4 μg/mL). Insecticidal agent 21 achieves multi-target neurotoxicity by inhibiting acetylcholinesterase (AChE) and simultaneously targeting other neural receptors (nicotinic acetylcholine receptors (nAChR), voltage-gated sodium channels (VGSC), and γ-aminobutyric acid receptors (GABAAR)). Insecticidal agent 21 has a strong insecticidal effect and can be used in the development of new insecticides to address the problem of mosquito resistance to traditional insecticides .

HY-N13754

Leptostachyol acetate	Parasite	Infection
Leptostachyol acetate is a lignan compound that can be isolated from the roots of Phryma leptostachya var. asiatica. Leptostachyol acetate exhibits larvicidal activity against mosquito larvae, with LC₅₀ values of 0.41, 2.1, and 2.3 ppm against third instar larvae of Culex pipiens pallens, Aedes aegypti, and Ocheratatos togoi, respectively. Leptostachyol acetate can be used for research on mosquito larval control .

HY-N14120

Opoponax oil Opopanax oil	Insecticide	Others
Opoponax oil is an effective insecticide against mosquito larvae .

HY-N3097R

Pellitorine (Standard)	Reference Standards TRP Channel Amyloid-β Toll-like Receptor (TLR) Keap1-Nrf2 Heme Oxygenase (HO) Dihydroorotate Dehydrogenase Ferroptosis PAI-1 NF-κB Proton Pump Glutathione Peroxidase Thrombin Insecticide Bacterial	Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Pellitorine (Standard) is the analytical standard of Pellitorine (HY-N3097). Pellitorine is a bioactive natural amide compound. Pellitorine can competitively antagonize the activation of TRPV1 by Capsaicin (HY-10448), thereby reducing pain signal transmission. Pellitorine improves cognitive dysfunction by upregulating the BDNF-ERK1/2-CREB and Nrf2-HO-1 pathways. Pellitorine exerts anti-inflammatory and anti-sepsis effects by inhibiting the release of high mobility group protein B1 (HMGB1) and the expression of RAGE/TLR4. Pellitorine exerts its antithrombotic effect by prolonging the clotting time, inhibiting the activity of clotting factors and thrombin. Pellitorine inhibits lipid peroxidation and resists ferroptosis by upregulating GPX4 and DHODH. Pellitorine kills Aedes aegypti mosquito larvae by inhibiting V-type H⁺-ATPase and aquaporin 4 (AaAQP4). Pellitorine exhibits anti-cancer activity (e.g., leukemia and breast cancer) and has inhibitory effects on certain bacteria.

HY-N11234A

(Z)-γ-Bisabolene	Insecticide	Infection
(Z)-γ-Bisabolene is a monocyclic bisabolane-type sesquiterpene hydrocarbon found in the essential oil of Galinsoga parviflora, acting as a mosquito larvicide and oviposition deterrent. (Z)-γ-Bisabolene induces acute toxicity in larvae of six mosquito species. (Z)-γ-Bisabolene deters oviposition in gravid females of six mosquito species. (Z)-γ-Bisabolene can be used for the research of malaria, dengue, japanese encephalitis, zika virus .

HY-W421914

Chlorthion	Insecticide	Infection
Chlorthion is an organic phosphorothionate insecticide. Chlorthion inhibits liver microsomal hydroxylation of testosterone .

Pellitorine	Alkaloids Classification of Application Fields Other Alkaloids Piperaceae Plants Disease Research Fields Piper nigrum Linn. Biological Pesticide Research Source Classification Cancer Agricultural Research	TRP Channel Amyloid-β Toll-like Receptor (TLR) Keap1-Nrf2 Heme Oxygenase (HO) Dihydroorotate Dehydrogenase Ferroptosis PAI-1 NF-κB ERK Proton Pump Glutathione Peroxidase Thrombin Insecticide Bacterial
Pellitorine is a bioactive natural amide compound. Pellitorine can competitively antagonize the activation of TRPV1 by Capsaicin (HY-10448), thereby reducing pain signal transmission. Pellitorine improves cognitive dysfunction by upregulating the BDNF-ERK1/2-CREB and Nrf2-HO-1 pathways. Pellitorine exerts anti-inflammatory and anti-sepsis effects by inhibiting the release of high mobility group protein B1 (HMGB1) and the expression of RAGE/TLR4. Pellitorine exerts its antithrombotic effect by prolonging the clotting time, inhibiting the activity of clotting factors and thrombin. Pellitorine inhibits lipid peroxidation and resists ferroptosis by upregulating GPX4 and DHODH. Pellitorine kills Aedes aegypti mosquito larvae by inhibiting V-type H⁺-ATPase and aquaporin 4 (AaAQP4). Pellitorine exhibits anti-cancer activity (e.g., leukemia and breast cancer) and has inhibitory effects on certain bacteria .

Nodulisporic acid A	Microorganisms Ketones, Aldehydes, Acids Source Classification	Parasite Insecticide
Nodulisporic acid A (Compound 1a) is an insecticidal agent. Nodulisporic acid A can isolated from fermentations of Nodulisporium sp. Nodulisporic acid A has a potent insecticidal activity against the larvae of the blowfly and mosquito with LC₅₀s of 0.5 and 0.3 ppm against A. aegypti and L. seracata, respectively. Nodulisporic acid A can be used for the development of insecticide .

Neoprocurcumenol	Natural Products Plants Curcuma aromatica Salisb. Source Classification Zingiberaceae	Parasite
Neoprocurcumenol is a larvicidal compound that exerts significant toxicity on mosquito larvae with LC₅₀ and LC ₉₀ values of 13.69 and 23.92 ppm, respectively .

Isoshinanolone	Natural Products Plumbago auriculata Lam. Plants Plumbaginaceae Source Classification	Others
Isoshinanolone is a natural product that can be extracted from Plumbago capensis. Isoshinanolone has mosquito larvicidal activity against fourth instar larvae of A. aegypti, with an IC₅₀ value of 1.26 μg/mL .

Cabraleadiol monoacetate Betulafolianediol 3-acetate; Cabraleadiol 3-acetate	Infection Triterpenes other families Classification of Application Fields Terpenoids Plants Disease Research Fields Source Classification	Others
Cabraleadiol monoacetate is a compound isolated from the lichen Pyxine consocians Vainio. Cabraleadiol monoacetate shows mosquito larvicidal activity against the second instar larvae of Aedes aegypti .

Leptostachyol acetate	Structural Classification Lignans Phryma leptostachya subsp. asiatica (Hara)Kitamura Phrymaceae Phenylpropanoids Plants Source Classification	Parasite
Leptostachyol acetate is a lignan compound that can be isolated from the roots of Phryma leptostachya var. asiatica. Leptostachyol acetate exhibits larvicidal activity against mosquito larvae, with LC₅₀ values of 0.41, 2.1, and 2.3 ppm against third instar larvae of Culex pipiens pallens, Aedes aegypti, and Ocheratatos togoi, respectively. Leptostachyol acetate can be used for research on mosquito larval control .

Opoponax oil Opopanax oil	Natural Products Apiaceae Opopanax hispidus Plants Source Classification	Insecticide
Opoponax oil is an effective insecticide against mosquito larvae .

Pellitorine (Standard)	Alkaloids Other Alkaloids Piperaceae Plants Piper nigrum Linn. Source Classification	Reference Standards TRP Channel Amyloid-β Toll-like Receptor (TLR) Keap1-Nrf2 Heme Oxygenase (HO) Dihydroorotate Dehydrogenase Ferroptosis PAI-1 NF-κB Proton Pump Glutathione Peroxidase Thrombin Insecticide Bacterial
Pellitorine (Standard) is the analytical standard of Pellitorine (HY-N3097). Pellitorine is a bioactive natural amide compound. Pellitorine can competitively antagonize the activation of TRPV1 by Capsaicin (HY-10448), thereby reducing pain signal transmission. Pellitorine improves cognitive dysfunction by upregulating the BDNF-ERK1/2-CREB and Nrf2-HO-1 pathways. Pellitorine exerts anti-inflammatory and anti-sepsis effects by inhibiting the release of high mobility group protein B1 (HMGB1) and the expression of RAGE/TLR4. Pellitorine exerts its antithrombotic effect by prolonging the clotting time, inhibiting the activity of clotting factors and thrombin. Pellitorine inhibits lipid peroxidation and resists ferroptosis by upregulating GPX4 and DHODH. Pellitorine kills Aedes aegypti mosquito larvae by inhibiting V-type H⁺-ATPase and aquaporin 4 (AaAQP4). Pellitorine exhibits anti-cancer activity (e.g., leukemia and breast cancer) and has inhibitory effects on certain bacteria.

(Z)-γ-Bisabolene	Structural Classification Terpenoids Sesquiterpenes Plants Compositae Swartzia polyphylla DC. Source Classification	Insecticide
(Z)-γ-Bisabolene is a monocyclic bisabolane-type sesquiterpene hydrocarbon found in the essential oil of Galinsoga parviflora, acting as a mosquito larvicide and oviposition deterrent. (Z)-γ-Bisabolene induces acute toxicity in larvae of six mosquito species. (Z)-γ-Bisabolene deters oviposition in gravid females of six mosquito species. (Z)-γ-Bisabolene can be used for the research of malaria, dengue, japanese encephalitis, zika virus .

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mosquito larvae

Inhibitors & Agonists

NaturalProducts

Natural
Products