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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
non-lysosomal
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "non-lysosomal" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P76735
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ASAH2; BCDase; N-Acylsphingosine Amidohydrolase 2; LCDase; Neutral Ceramidase; NCDase; non-lysosomal Ceramidase; HNAC1; N-Acylsphingosine Amidohydrolase (non-lysosomal Ceramidase) 2; Neutral/Alkaline Ceramidase; Acylsphingosine Deacylase 2; Mitochondrial
Species:
Mouse
Source:
HEK293
Synonyms: ACT-519276; OGT2378
Target:
Research Areas:
Sinbaglustat (OGT2378) is a dual inhibitor of glucosylceramide synthase (GCS) and non-lysosomal glucosyl ceramidase (GBA2). Sinbaglustat is an orally available N-alkyl iminosugar that crosses the blood-brain barrier. Sinbaglustat can be used for the research of central neurodegenerative diseases associated with lysosomal dysfunctions .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
