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ocular antihypertensive agents

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-136492
    Acetylclonidine

    		Drug Derivative Others
    Acetylclonidine is a derivative of Clonidine (HY-12721). Acetylclonidine is promising for research of ocular antihypertensive agents for glaucoma .
    Acetylclonidine
  • HY-16183A
    Echothiopate chloride

    Echothiophate chloride

    		 Cholinesterase (ChE) Cardiovascular Disease
    Echothiophate (Echothiophate) chloride is a highly effective, long-lasting cholinesterase inhibitor employed as a miotic for managing glaucoma. Echothiopate chloride forms a covalent bond with the serine residue at the active site of cholinesterase through its phosphate group, rendering the enzyme permanently inactive and necessitating the synthesis of new enzymes by the cell. Given its irreversible binding to cholinesterase and the extremely slow rate of hydrolysis, the effects of echothiophate can persist for a week or longer. Echothiopate chloride is utilized as an ocular antihypertensive agent in the treatment of chronic glaucoma and, in certain cases, accommodative esotropia.
    Echothiopate chloride

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