54707-71-0
54707-71-0
Chemical Structure
Acetylclonidine
- CAS No.: 54707-71-0
- Formula:C11H11Cl2N3O
- Molecular Weight:272.13
IUPAC Name: 1-(2-((2,6-dichlorophenyl)amino)-4,5-dihydro-1H-imidazol-1-yl)ethan-1-one
InChIKey: AFINVMDZLRAKEV-UHFFFAOYSA-N
SMILES: CC(N1CCN=C1NC2=C(Cl)C=CC=C2Cl)=O
Biological Activity: Acetylclonidine is a derivative of Clonidine (HY-12721). Acetylclonidine is promising for research of ocular antihypertensive agents for glaucoma[1][2].
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Acetylclonidine | Acetylclonidine is a derivative of Clonidine (HY-12721). Acetylclonidine is promising for research of ocular antihypertensive agents for glaucoma. | |||||||||||||||||||||
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Acetylclonidine-d4 | Acetylclonidine-d4 is the deuterium labeled Acetylclonidine. | |||||||||||||||||||||
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References
- [1]. Jen T, et al. Amidines and related compounds. 6. Studies on structure-activity relationships of antihypertensive and antisecretory agents related to clonidine. J Med Chem. 1975 Jan;18(1):90-9. [Content Brief]
- [2]. Huber D, et al. Synthesis and ocular antihypertensive activity of new imidazolidine derivatives containing a beta-blocking side chain. J Med Chem. 1991 Nov;34(11):3197-204. [Content Brief]
Keywords
