26 Results for "

oxindole

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "oxindole" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-N0901
CAS No.: 6877-32-3
Corynoxine, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria rhynchophylla. Corynoxine is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway .
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3
3 Cited Publications
Cat. No.: HY-Y0061
CAS No.: 59-48-3
Synonyms: 2-Indolinone
Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.
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Cat. No.: HY-59227
CAS No.: 99365-40-9
Synonyms: 6-Bromo-2-oxindole
6-Bromo-2-oxindole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-N4157
CAS No.: 5171-37-9
Isopteropodine is a positive modulator that selectively acts on muscarinic M1 and 5-HT2 receptors. Isopteropodine has an EC50 of 9.92 μM for acetylcholine and 14.5 μM for 5-HT. Isopteropodine also has antibacterial activity against Gram-positive bacteria, with MICs of 150 μg/mL and 250 μg/mL for Staphylococcus aureus and Bacillus subtilis, respectively. Isopteropodine enhances receptor function by increasing the affinity of agonists for receptors and can also inhibit the growth of specific Gram-positive bacteria, and can be used in cognitive impairment and antibacterial research .
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Cat. No.: HY-W009666
CAS No.: 118289-55-7
Target:  

Dopamine Transporter

Research Areas:  

Others

6-Chloro-5-(2-chloroethyl)oxindole (Imp Z2) is an impurity of Ziprasidone (HY-14542), a substrate of the human dopamine transporter (hDAT) .
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Cat. No.: HY-116959
CAS No.: 259667-25-9
Target:  

GHSR

Research Areas:  

Metabolic Disease

SM-130686 is an oxindole derivative and an active GH secretagogue (GHS). SM-130686 stimulates GH release with a Half-maximum stimulation of 6.3 nM. SM-130686 has an orally active .
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Cat. No.: HY-N4156
CAS No.: 5629-60-7
Pteropodine (compound 3) is a monoterpenoid oxindole alkaloid that can be isolated from Hamelia patens. Pteropodine modulates the functions of M1 muscarinic and 5-HT2 receptors. Pteropodine has antioxidant and antimutagenic properties .
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Cat. No.: HY-120720
CAS No.: 4963-01-3
Isomitraphylline, an oxindole alkaloid, has potent anti-cancer activity .
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Cat. No.: HY-N9163
CAS No.: 6899-73-6
Uncarine A is a oxindole alkaloid, which can be isolated from Ulzcaria berlzaysii F. Muell .
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Cat. No.: HY-N16467
CAS No.: 14019-66-0
Synonyms: Speciofiline
Uncarine F (Speciofiline) is a pentacyclic oxindole alkaloid found in Uncaria tomentosa. Uncaria alkaloids have wide medicinal properties, including neuroprotective, anticancer, and antihypertensive activities. Uncaria alkaloids may stimulate the immune system, relax smooth muscles, dilate blood vessels, and act as a diuretic. Uncarine F can be used for the researches of cancer, immunology, cardiovascular and neurological disease .
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Cat. No.: HY-W746828
CAS No.: 2724918-56-1
Oxindole-3-acetic acid- 13C6 is 13C labeled Oxindole-3-acetic acid .
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Cat. No.: HY-Y0061R
CAS No.: 59-48-3
Synonyms: 2-Indolinone (Standard)
Oxindole (Standard) is the analytical standard of Oxindole. This product is intended for research and analytical applications. Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.
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Cat. No.: HY-108444
CAS No.: 1137967-28-2
Purity:  99.62%
Target:  

VEGFR

Research Areas:  

Cancer

(Z)-FeCP-oxindole is a selective human vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with an IC50 value of 200 nM. (Z)-FeCP-oxindole can significantly inhibit VEGFR1 and PDGFRa or b at 10 μM. (Z)-FeCP-oxindole has some anticancer activity, acting on B16 murine melanoma lines with IC50 less than 1 μM .
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Cat. No.: HY-108444A
CAS No.: 884338-18-5
Target:  

VEGFR

Research Areas:  

Cancer

(Z)-FeCP-oxindole is a selective human vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with an IC50 value of 200 nM. (Z)-FeCP-oxindole can significantly inhibit VEGFR1 and PDGFRa or b at 10 μM. (Z)-FeCP-oxindole has some anticancer activity, acting on B16 murine melanoma lines with IC50 less than 1 μM .
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Cat. No.: HY-117034
CAS No.: 106466-66-4
Rankinidine is an oxindole alkaloid that is isolated from the MeOH extract of the stem of Gelsemium rankinii .
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Cat. No.: HY-N0901B
Corynoxine hydrochloride, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria macrophylla. Corynoxine hydrochloride is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway .
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Cat. No.: HY-115943
CAS No.: 2907774-88-1
Target:  

CDK

Research Areas:  

Cancer

Anticancer agent 30 (compound 6f-Z), a 3-arylidene-2-oxindole derivative, is a selective CDK2 inhibitor with potent anticancer activity .
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Cat. No.: HY-169359
Target:  

Ligands for E3 Ligase

Research Areas:  

Others

4-Methylphenoxyacetic acid-Oxindole-CF3 is the E3 ligase ligand part of L134 (HY-169358). 4-Methylphenoxyacetic acid-Oxindole-CF3 can be utilized in PROTAC synthesis .
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Cat. No.: HY-114023
CAS No.: 851681-89-5
Research Areas:  

Neurological Disease

BML-288 (compound Oxindole 1) is a potent PDE2 inhibitor with an IC50 value of 40 nM. BML-288 has the potential for the research of osteoarthritis pain .
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Cat. No.: HY-N4157R
CAS No.: 5171-37-9
Isopteropodine (Standard) is the analytical standard of Isopteropodine (HY-N4157). This product is intended for research and analytical applications. Isopteropodine is a positive modulator that selectively acts on muscarinic M1 and 5-HT2 receptors. Isopteropodine has an EC50 of 9.92 μM for acetylcholine and 14.5 μM for 5-HT. Isopteropodine also has antibacterial activity against Gram-positive bacteria, with MICs of 150 μg/mL and 250 μg/mL for Staphylococcus aureus and Bacillus subtilis, respectively. Isopteropodine enhances receptor function by increasing the affinity of agonists for receptors and can also inhibit the growth of specific Gram-positive bacteria, and can be used in cognitive impairment and antibacterial research .
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