884338-18-5
884338-18-5
Chemical Structure
(E)-FeCP-oxindole
- CAS No.: 884338-18-5
- Formula:C19H15FeNO
- Molecular Weight:329.17
SMILES: [][Fe][].O=C1NC2=C(C=CC=C2)/C1=C\c3cccc3.c4cccc4
Biological Activity:
(Z)-FeCP-oxindole is a selective human vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with an IC50 value of 200 nM. (Z)-FeCP-oxindole can significantly inhibit VEGFR1 and PDGFRa or b at 10 μM. (Z)-FeCP-oxindole has some anticancer activity, acting on B16 murine melanoma lines with IC50 less than 1 μM[1].
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(E)-FeCP-oxindole | (Z)-FeCP-oxindole is a selective human vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with an IC50 value of 200 nM. (Z)-FeCP-oxindole can significantly inhibit VEGFR1 and PDGFRa or b at 10 μM. (Z)-FeCP-oxindole has some anticancer activity, acting on B16 murine melanoma lines with IC50 less than 1 μM. |
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References
Keywords
