BML-288
BML-288 (compound Oxindole 1) is a potent PDE2 inhibitor with an IC50 value of 40 nM. BML-288 has the potential for the research of osteoarthritis pain.
For research use only. We do not sell to patients.
- CAS No.: 851681-89-5
- Formula: C14H10N4O3S
- Molecular Weight:314.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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PDE2 40 nM (IC50) |
Chemical Information
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CAS No. 851681-89-5
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Molecular Weight 314.32
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Formula C14H10N4O3S
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SMILES
O=C(C1C(N(C)C2=C1C=C(OC=C3)C3=C2)=O)NC4=NN=CS4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Plummer MS, et al. Discovery of potent, selective, bioavailable phosphodiesterase 2 (PDE2) inhibitors active in an osteoarthritis pain model, part I: transformation of selective pyrazolodiazepinone phosphodiesterase 4 (PDE4) inhibitors into selective PDE2 inhibitors. Bioorg Med Chem Lett. 2013 Jun 1;23(11):3438-42. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BML-288 Related Classifications
HY-114023 Related Classifications
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