6877-32-3
6877-32-3
Chemical Structure
Corynoxine
- CAS No.: 6877-32-3
- Formula:C22H28N2O4
- Molecular Weight:384.47
IUPAC Name: methyl (E)-2-((3S,6'S,7'S,8a'S)-6'-ethyl-2-oxo-2',3',6',7',8',8a'-hexahydro-5'H-spiro[indoline-3,1'-indolizin]-7'-yl)-3-methoxyacrylate
InChIKey: DAXYUDFNWXHGBE-NRAMRBJXSA-N
SMILES: O=C(NC1=C2C=CC=C1)[C@@]32[C@@](C[C@H](/C(C(OC)=O)=C\OC)[C@H](CC)C4)([H])N4CC3
Biological Activity: Corynoxine, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria rhynchophylla. Corynoxine is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway[1].
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Corynoxine | 99.89% | Corynoxine, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria rhynchophylla. Corynoxine is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-N0387RRhynchophylline (Standard) -
Similarity Score 1.00
HY-N0766RIsorhynchophylline (Standard) -
Similarity Score 1.00
HY-N0901ACorynoxine B -
Similarity Score 0.87
HY-N0590RCorynoxeine (Standard) -
Similarity Score 0.87
HY-N0775Isocorynoxeine -
Similarity Score 0.70
HY-120720Isomitraphylline -
Similarity Score 0.70
HY-N16467Uncarine F -
Similarity Score 0.70
HY-N4156Pteropodine -
Similarity Score 0.70
HY-N4157Isopteropodine -
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