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Cat. No.: HY-116959

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SM-130686

SM-130686 is an oxindole derivative and an active GH secretagogue (GHS). SM-130686 stimulates GH release with a Half-maximum stimulation of 6.3 nM. SM-130686 has an orally active.

For research use only. We do not sell to patients.

CAS No.: 259667-25-9
Formula: C₂₂H₂₄Cl₂F₃N₃O₃
Molecular Weight:506.35

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

SM-130686 Chemical Structure

CAS No.: 259667-25-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

SM-130686 is an oxindole derivative and an active GH secretagogue (GHS). SM-130686 stimulates GH release with a Half-maximum stimulation of 6.3 nM. SM-130686 has an orally active^[1].

All GHSR Isoforms :

GHSR1a

Chemical Information

CAS No. 259667-25-9
Molecular Weight 506.35
Formula C₂₂H₂₄Cl₂F₃N₃O₃
SMILES

O[C@]1(C2=C(C=CC=C2)Cl)C3=C(C(F)(F)F)C=C(C(N)=O)C=C3N(C1=O)CCN(CC)CC.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. J Nagamine, et al. Pharmacological profile of a new orally active growth hormone secretagogue, SM-130686. J Endocrinol. 2001 Dec;171(3):481-9. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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