2. Search Result
Search Result
Results for "

oxygenation

" in MedChemExpress (MCE) Product Catalog:

57

Inhibitors & Agonists

1

Screening Libraries

29

Natural
Products

5

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-13619
    Efaproxiral
    1 Publications Verification

    RSR13

    		 Hemoglobin Infection Cancer
    Efaproxiral (RSR13) is a haemoglobin (Hb) synthetic allosteric modifier. Efaproxiral decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy .
    Efaproxiral
  • HY-N1511
    Ganoderic acid D
    2 Publications Verification

    		 Sirtuin Apoptosis Cancer
    Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells . Ganoderic acid D induces HeLa human cervical carcinoma apoptosis .
    Ganoderic acid D
  • HY-111664A
    (S)​-​(-​)​-​Citronellal

    (-​)​-​Citronellal

    		 Drug Isomer Cancer
    (S)-(-)-Citronellal ((-​)​-​Citronellal) is an oxygenated monoterpenoid found in Citrus limon (L.) Burm. F. essential oils. (S)-(-)-Citronellal is a chiral isomers of (R)-(+)-Citronellal (HY-111664) and does not possess microtubule-disrupting activity. (S)-(-)-Citronellal can be used for cancer research .
    (S)​-​(-​)​-​Citronellal
  • HY-W020246
    Tetramethylthiuram monosulfide

    TMTM

    		 Squalene Monooxygenase Bacterial Infection Inflammation/Immunology
    Tetramethylthiuram monosulfide (TMTM) is an orally active microsomal monooxygenases inhibitor. Tetramethylthiuram monosulfide is used as an accelerator and activator in the processing of natural rubber and butyl rubber. Tetramethylthiuram monosulfide reduces palmitic acid incorporation into microsomal phospholipids, disrupts microsomal membrane integrity, and impairs electron transport during oxygenation. Tetramethylthiuram monosulfide can be used for the research of fungal infection, bacterial infection and allergic contact dermatitis .
    Tetramethylthiuram monosulfide
  • HY-N7117
    1,4-Cineole

    		Environmental Pollutants TRP Channel Neurological Disease
    1,4-Cineole is an oxygenated monoterpene found in eucalyptus oil. 1,4-Cineole is a hTRPM8 and hTRPA1 agonist. 1,4-Cineole can increase intracellular Ca 2+ concentration. 1,4-Cineole exhibits anti-anxiety and anti-depression effects. 1,4-Cineole can be used for the research of neurological disease, such as depression .
    1,4-Cineole
  • HY-N12804
    δ-Cadinol

    (-)-Torreyol

    		 Others Others
    δ-Cadinol ((-)-Torreyol) is an oxygenated sesquiterpene and can be isolated from Lepechinia salviae (Lindl.) Epling .
    δ-Cadinol
  • HY-13619A
    Efaproxiral sodium
    1 Publications Verification

    RSR13 sodium

    		 Hemoglobin Infection Cancer
    Efaproxiral (RSR13) sodium is a haemoglobin (Hb) synthetic allosteric modifier. Efaproxiral sodium decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy .
    Efaproxiral sodium
  • HY-156613
    Frunexian

    EP-7041

    		 Factor XI Infection
    Frunexian (EP-7041) is a selective and potent inhibitor of coagulation factor XI/activated factor XI, targeting to factor XIa. Frunexian exhibits antithrombotic activity, with no bleeding liability in rat mesenteric arterial puncture model. Frunexian can be used in extracorporeal membrane oxygenation (ECMO) research .
    Frunexian
  • HY-B1555
    Benzyl nicotinate

    		Liposome Cardiovascular Disease
    Benzyl nicotinate is a vasodilator that increases skin oxygenation levels by increasing skin blood flow .
    Benzyl nicotinate
  • HY-N2221
    Ganoderal A

    		Others Metabolic Disease
    Ganoderal A, an oxygenated sterol from G. lucidum, is a cholesterol synthesis inhibitor .
    Ganoderal A
  • HY-130239
    14(S)-HDHA

    14(S)-HDoHE

    		 Drug Metabolite Neurological Disease
    14(S)-HDHA (14(S)-HDoHE) is an oxygenation product of Docosahexaenoic acid (DHA). 14(S)-HDHA is a marker reflecting activation of a Docosahexaenoic acid carbon 14-lipoxygenation pathway .
    14(S)-HDHA
  • HY-130239A
    (±)14-HDHA

    (±)14-HDoHE; 14-hydroxy Docosahexaenoic acid; (±)14-HDoHE

    		 Drug Metabolite Neurological Disease
    (±)14-HDHA is the isomer of 14(S)-HDHA (HY-130239). 14(S)-HDHA is an oxygenation product of Docosahexaenoic acid (DHA). 14(S)-HDHA is a marker reflecting activation of a Docosahexaenoic acid carbon 14-lipoxygenation pathway .
    (±)14-HDHA
  • HY-106784A
    (E)-Ajoene

    		Fungal Apoptosis Neurological Disease
    (E)-Ajoene is a oxygenated ajoene and organosulfur compound, which can be acquired via allicin decomposing. The polysulfides from garlic can be converted by human red blood cells into hydrogen sulfide (H2S) and allyl glutathione. (E)-Ajoene has been proved to show neuroprotective effects against ischemic damage. (E)-Ajoene is orally active to inhibit lipid peroxidation. (E)-Ajoene increases the number of cresyl violet-positive neurons and decreases the number of reactive gliosis in the CA1 region .
    (E)-Ajoene
  • HY-N17260
    Phellandral

    		Bacterial Infection
    Phellandral is an aldehyde compound that can be found in Eucalyptus camaldulensis and Thymus seravschanicus. The phellandral-containing eucalyptus essential oil exhibits significant inhibitory effects on various plant pathogenic fungi, especially on Aspergillus flavus. Phellandral, together with other oxygenated monoterpenoids, constitutes an important basis for the antibacterial activity of the essential oil .
    Phellandral
  • HY-132849
    Nezulcitinib

    TD-0903

    		 JAK Infection Inflammation/Immunology
    Nezulcitinib (TD-0903) is an inhaled and lung-selective pan-Janus kinase (JAK) inhibitor. Nezulcitinib can be used for the research of COVID-19 associated acute lung injury and impaired oxygenation .
    Nezulcitinib
  • HY-N7731A
    (-)-Lavandulol

    (R)-Lavandulol

    		 Others Others
    (-)-Lavandulol is the isomer of (±)-Lavandulol (HY-N7731). (±)-Lavandulol is an irregular monoterpene alcohol. (±)-Lavandulol can be transformed by a fungal strain Rhizopus oryzae into corresponding oxygenated metabolite .
    (-)-Lavandulol
  • HY-118736
    Ganodermic acid S

    		Others Cardiovascular Disease
    Ganodermic acid S is an oxygenated triterpenoid, that can be isolated from the Chinese medicinal fungus Ganoderma lucidum (Fr.) Karst (Polyporaceae). Ganodermic acid S exerts a concentration dependent inhibition on the response of human gel-filtered platelets (GFP) to U-46619 (HY-108566), a thromboxane (TX) A2 mimetic .
    Ganodermic acid S
  • HY-77839S1
    Cortodoxone-d2

    11-Deoxycortisol-d2; cortexolone-d2; Reichstein's substance S-d2

    		 Isotope-Labeled Compounds Glucocorticoid Receptor Endogenous Metabolite Inflammation/Immunology Endocrinology
    Cortodoxone-d2 is the deuterium labeled Cortodoxone. Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone) .
    Cortodoxone-d2
  • HY-120893
    trans-4,5-Epoxy-(E)-2-decenal

    		Endogenous Metabolite Others
    trans-4,5-Epoxy-(E)-2-decenal is an oxygenated α,β-unsaturated aldehyde found in mammalian blood that gives blood its characteristic metallic odor. It is used by predators to locate blood or prey .
    trans-4,5-Epoxy-(E)-2-decenal
  • HY-N10210
    Saccharothrixin F

    		Bacterial Infection
    Saccharothrixin F is a highly oxygenated saccharothrixin, with antibacterial and anti-inflammatory activities .
    Saccharothrixin F
  • HY-N1108
    Uvedalin

    		Others Others
    Uvedalin is a conjugated γ-lactone and oxygenated germacranolide that can be isolated from Polymnia uvedalia (L.) .
    Uvedalin
  • HY-N6957
    8-Keto-berberine

    		Drug Derivative Metabolic Disease
    8-Keto-berberine (compound 29) is a non-naturally occurring 11, 12-oxygenated protoberberine derived from naturally occurring 9, 10-oxygenated protoberberine .
    8-Keto-berberine
  • HY-113351
    11β-Hydroxyandrosterone
    1 Publications Verification

    		 Endogenous Metabolite Endocrinology
    11β-Hydroxyandrosterone is a 11-oxygenated androgen metabolite of 11β-hydroxyandrostenedione .
    11β-Hydroxyandrosterone
  • HY-N1511R
    Ganoderic acid D (Standard)

    		Reference Standards Sirtuin Apoptosis Cancer
    Ganoderic acid D (Standard) is the analytical standard of Ganoderic acid D. This product is intended for research and analytical applications. Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells . Ganoderic acid D induces HeLa human cervical carcinoma apoptosis .
    Ganoderic acid D (Standard)
  • HY-W979008
    (+)-Isopinocampheol

    		Drug Intermediate Fungal Others
    (+)-Isopinocampheol is an oxygenated monoterpenoid that is important in the chemical ecology of bark beetles .
    (+)-Isopinocampheol
  • HY-121083
    Aerugidiol

    		Others Others
    Aerugidiol is a bridge-head oxygenated sesquiterpene isolated from the rhizomes of Curcuma aeruginosa .
    Aerugidiol
  • HY-N8712R
    Umckalin (Standard)

    		Reference Standards p38 MAPK JNK ERK TNF Receptor Interleukin Related PI3K Akt Others
    Umckalin (Standard) is the analytical standard of Umckalin (HY-N8712). Umckalin is Coumarin (HY-N0709) derivative that exhibits anti-inflammatory properties. Umckalin reduces phosphorylation of p38 MAPK, JNK, and ERK, lowers TNF-α, IL-6, IL-1β, NO, and PGE2 production. Umckalin can be used for the research of chronic inflammatory diseases .
    Umckalin (Standard)
  • HY-N1197
    Subelliptenone G

    1,4,5-Trihydroxyxanthone

    		 Others Others
    Subelliptenone G is a simple oxygenated xanthone that can be isolated from the root bark of Garcinia subelliptica .
    Subelliptenone G
  • HY-N7731
    (±)-Lavandulol

    		Others Others
    (±)-Lavandulol is an irregular monoterpene alcohol. (±)-Lavandulol can be transformed by a fungal strain Rhizopus oryzae into corresponding oxygenated metabolite .
    (±)-Lavandulol
  • HY-N10934
    Ganoderic acid GS-1

    		HIV Protease Infection
    Ganoderic acid GS-1, a highly oxygenated lanostane-type triterpenoid, has anti-HIV-1 protease activities with an IC50 of 58 μM .
    Ganoderic acid GS-1
  • HY-N1621
    1-Deacetylnimbolinin B

    		Fungal Parasite Infection
    1-Deacetylnimbolinin B is a nimbolinin-type limonoid isolated from the fruits of Melia toosendan. Limonoids are a class of highly oxygenated nortriterpenoids that exhibit insecticidal, antifungal, nematicidal and cytotoxic properties .
    1-Deacetylnimbolinin B
  • HY-N7731R
    (±)-Lavandulol (Standard)

    		Others Reference Standards Others
    (±)-Lavandulol (Standard) is the analytical standard of (±)-Lavandulol. This product is intended for research and analytical applications. (±)-Lavandulol is an irregular monoterpene alcohol. (±)-Lavandulol can be transformed by a fungal strain Rhizopus oryzae into corresponding oxygenated metabolite .
    (±)-Lavandulol (Standard)
  • HY-B1555R
    Benzyl nicotinate (Standard)

    		Reference Standards Liposome Cardiovascular Disease
    Benzyl nicotinate (Standard) is the analytical standard of Benzyl nicotinate. This product is intended for research and analytical applications. Benzyl nicotinate is a vasodilator that increases skin oxygenation levels by increasing skin blood flow .
    Benzyl nicotinate (Standard)
  • HY-N10082
    Trigoxyphin A

    		Others Cancer
    Trigoxyphin A is a oxygenated daphnane-type diterpenoids. Trigoxyphin A exhibites strong cytotoxic activity against HL60 and A549 with IC50s of 0.27 and 7.5 μM, respectively .
    Trigoxyphin A
  • HY-117358
    KW-5805

    		Others Inflammation/Immunology
    KW-5805 is an anti-ulcer agent that promotes the biosynthesis, storage and secretion of gastric mucus, improves gastric mucosal hemodynamics, and inhibits the decrease in gastric mucosal blood volume and mucosal oxygenation caused by steroid shock .
    KW-5805
  • HY-13619S
    Efaproxiral-d6

    RSR13-d6

    		 Isotope-Labeled Compounds Cancer
    Efaproxiral (RSR13)-d6 is the deuterium labeled Efaproxiral (HY-13619). Efaproxiral is a haemoglobin (Hb) synthetic allosteric modifier. Efaproxiral decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy .
    Efaproxiral-d6
  • HY-13619AR
    Efaproxiral sodium (Standard)

    RSR13 sodium (Standard)

    		 Reference Standards Cancer
    Efaproxiral (RSR13) sodium (Standard) is the analytical standard of Efaproxiral sodium (HY-13619A). This product is intended for research and analytical applications. Efaproxiral sodium is a haemoglobin (Hb) synthetic allosteric modifier. Efaproxiral sodium decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy .
    Efaproxiral sodium (Standard)
  • HY-13619R
    Efaproxiral (Standard)

    RSR13 (Standard)

    		 Reference Standards Cancer
    Efaproxiral (RSR13) (Standard) is the analytical standard of Efaproxiral (HY-13619). This product is intended for research and analytical applications. Efaproxiral is a haemoglobin (Hb) synthetic allosteric modifier. Efaproxiral decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy .
    Efaproxiral (Standard)
  • HY-121996
    Prostaglandin E2 Ethanolamide

    PGE2 ethanolamide

    		 Prostaglandin Receptor COX Inflammation/Immunology
    Prostaglandin E2 Ethanolamide (PGE2-EA), an analog of PGE2, can be formed enzymatically following COX-2 oxygenation of endocannabinoids. Prostaglandin E2 Ethanolamide (PGE2-EA) could modulate the production of the proinflammatory cytokine TNF-α in human blood and human monocytic cells .
    Prostaglandin E2 Ethanolamide
  • HY-130239S
    14(S)-HDHA-d5

    14(S)-HDoHE-d5

    		 Isotope-Labeled Compounds Drug Metabolite Neurological Disease
    14(S)-HDHA-d5 (14(S)-HDoHE-d5) is deuterium labeled 14(S)-HDHA. 14(S)-HDHA (14(S)-HDoHE) is an oxygenation product of Docosahexaenoic acid (DHA). 14(S)-HDHA is a marker reflecting activation of a Docosahexaenoic acid carbon 14-lipoxygenation pathway .
    14(S)-HDHA-d5
  • HY-122282
    AZ11657312

    		Angiotensin Receptor Cardiovascular Disease
    AZ11657312 is a P2X7 receptor antagonist with activity to restore stress natriuresis. AZ11657312 significantly increased renal medullary perfusion, only in mice treated with angiotensin II. AZ11657312 improves tissue oxygenation by blocking P2X7R, especially in areas of the kidney that are underoxygenated. Administration of AZ11657312 increased sodium excretion up to sixfold while normalizing blood pressure .
    AZ11657312
  • HY-P2744
    Ribulose bisphosphate carboxylase

    Ribulose 1,5-bisphosphate carboxylase

    		 Biochemical Assay Reagents Others
    Ribulose bisphosphate carboxylase (Ribulose 1,5-bisphosphate carboxylase) catalyses the carboxylation (CO2 addition) or oxygenation (O2 addition) of d-ribulose-1,5-bisphosphate (RuBP) and the subsequent carbon–carbon cleavage to form two molecules of 3-phospho-d-glycerate (PGA) (with CO2) or one molecule of PGA and one molecule of 2-phospho-glycolate (PG; with O2) .
    Ribulose bisphosphate carboxylase
  • HY-N7117R
    1,4-Cineole (Standard)

    		Reference Standards TRP Channel Neurological Disease
    1,4-Cineole (Standard) is the analytical standard of 1,4-Cineole (HY-N7117). 1,4-Cineole is an oxygenated monoterpene found in eucalyptus oil. 1,4-Cineole is a hTRPM8 and hTRPA1 agonist. 1,4-Cineole can increase intracellular Ca 2+ concentration. 1,4-Cineole exhibits anti-anxiety and anti-depression effects. 1,4-Cineole can be used for the research of neurological disease, such as depression .
    1,4-Cineole (Standard)
  • HY-139938
    (±)11(12)-EET methyl ester

    11,12-EET methyl ester; (±)11,12-EpETrE methyl ester

    		 Drug Derivative Cardiovascular Disease Inflammation/Immunology
    (±)11(12)-EET methyl ester (11,12-EET-methyl ester) is a methylated derivative of 11,12-epoxyeicosatrienoic acid (11,12-EET) (HY-130494). (±)11(12)-EET methyl ester cannot induce β-arrestin recruitment of the G protein-coupled receptor GPR132. (±)11(12)-EET methyl ester fails to enhance the expression of hematopoietic stem and progenitor cell (HSPC) markers. (±)11(12)-EET methyl ester can be used as a negative control molecule to study the structure-function relationship of 11,12-EET, facilitating the analysis of the role of the oxygenated fatty acid-GPR132 signaling axis in hematopoiesis .
    (±)11(12)-EET methyl ester
  • HY-139938S
    (±)11(12)-EET methyl ester-d11

    11,12-EET methyl ester-d11; (±)11,12-EpETrE methyl ester-d11

    		 Isotope-Labeled Compounds Cardiovascular Disease Inflammation/Immunology
    (±)11(12)-EET-d11 methyl ester (11,12-EET methyl ester-d11) is the deuterium labeled (±)11(12)-EET methyl ester (HY-139938). (±)11(12)-EET methyl ester (11,12-EET-methyl ester) is a methylated derivative of 11,12-epoxyeicosatrienoic acid (11,12-EET) (HY-130494). (±)11(12)-EET methyl ester cannot induce β-arrestin recruitment of the G protein-coupled receptor GPR132. (±)11(12)-EET methyl ester fails to enhance the expression of hematopoietic stem and progenitor cell (HSPC) markers. (±)11(12)-EET methyl ester can be used as a negative control molecule to study the structure-function relationship of 11,12-EET, facilitating the analysis of the role of the oxygenated fatty acid-GPR132 signaling axis in hematopoiesis .
    (±)11(12)-EET methyl ester-d11
  • HY-N18056
    (+)-Norpatchoulenol

    		Others Others
    (+)-Norpatchoulenol is an oxygenated sesquiterpene. (+)-Norpatchoulenol exists in the essential oil of Pogostemon patchouli .
    (+)-Norpatchoulenol
  • HY-N16514
    8(S)-HPETE

    		Others Others
    8(S)-HPETE, short for 8(S)-hydroperoxy-5Z,9E,11Z,14Z-eicosatetraenoic acid, is a major oxygenation product generated when arachidonic acid acts as a substrate for the lipoxygenase purified from ripe tomato fruits .
    8(S)-HPETE
  • HY-105095
    Doranidazole

    PR 350; RP 343

    		 Biochemical Assay Reagents Cancer
    Doranidazole (PR 350) is a radiosensitizer. Doranidazole increases the radiosensitivity of hypoxic SCCVII cells. Doranidazole significantly enhances radiation-induced growth delay in SCCVII tumors when administered intravenously before tumor irradiation. Doranidazole radiosensitizes tumors to an extent that depends on the tumor's oxygenation status. Doranidazole can be used for the study of lymphoma and hypoxic pancreatic tumors .
    Doranidazole
  • HY-E71040
    Cyclohexanone Monooxygenase, Acinetobacter sp.

    		Biochemical Assay Reagents Others
    Cyclohexanone Monooxygenase, Acinetobacter sp. (EC 1.14.13.22) is a versatile oxygenation catalyst. Cyclohexanone Monooxygenase, Acinetobacter sp. (EC 1.14.13.22) uses the bound FAD-4a-OOH oxygenating intermediate to initiate transfer of oxygen to electrophilic substrate sites. Cyclohexanone Monooxygenase, Acinetobacter sp. (EC 1.14.13.22) is also capable of oxygenating at nitrogen, trivalent phosphorus, and boron sites in boronic acids.
    Cyclohexanone Monooxygenase, Acinetobacter sp.
  • HY-142064
    30-Hydroxytriacontanoic acid

    ω-Hydroxytriacontanoic acid

    		 Biochemical Assay Reagents Others
    30-Hydroxytriacontanoic acid (ω-Hydroxytriacontanoic acid) is a oxygenated fatty acid .
    30-Hydroxytriacontanoic acid

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: