470-67-7
470-67-7
Chemical Structure
1,4-Cineole
- CAS No.: 470-67-7
- Formula:C10H18O
- Molecular Weight:154.25
IUPAC Name: 1-isopropyl-4-methyl-7-oxabicyclo[2.2.1]heptane
InChIKey: RFFOTVCVTJUTAD-UHFFFAOYSA-N
SMILES: CC(C12CCC(O2)(C)CC1)C
Biological Activity: 1,4-Cineole is an oxygenated monoterpene found in eucalyptus oil. 1,4-Cineole is a hTRPM8 and hTRPA1 agonist. 1,4-Cineole can increase intracellular Ca2+ concentration. 1,4-Cineole exhibits anti-anxiety and anti-depression effects. 1,4-Cineole can be used for the research of neurological disease, such as depression [1][2].
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1,4-Cineole | 95.0% | 1,4-Cineole is an oxygenated monoterpene found in eucalyptus oil. 1,4-Cineole is a hTRPM8 and hTRPA1 agonist. 1,4-Cineole can increase intracellular Ca2+ concentration. 1,4-Cineole exhibits anti-anxiety and anti-depression effects. 1,4-Cineole can be used for the research of neurological disease, such as depression . | ||||||||||||||||||||
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1,4-Cineole (Standard) | 94.50% | 1,4-Cineole (Standard) is the analytical standard of 1,4-Cineole (HY-N7117). 1,4-Cineole is an oxygenated monoterpene found in eucalyptus oil. 1,4-Cineole is a hTRPM8 and hTRPA1 agonist. 1,4-Cineole can increase intracellular Ca2+ concentration. 1,4-Cineole exhibits anti-anxiety and anti-depression effects. 1,4-Cineole can be used for the research of neurological disease, such as depression . | ||||||||||||||||||||
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References
- [1]. Takaishi M, et al. 1,8-cineole, a TRPM8 agonist, is a novel natural antagonist of human TRPA1. Mol Pain. 2012 Nov 29;8:86. [Content Brief]
- [2]. Dougnon G, et al. Inhalation Administration of the Bicyclic Ethers 1,8- and 1,4-cineole Prevent Anxiety and Depressive-Like Behaviours in Mice. Molecules. 2020 Apr 18;25(8):1884. [Content Brief]
