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Results for "

p75NTR

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (6) Drug Isomer (1) Neurokinin Receptor (2) Neurotensin Receptor (2) Reference Standards (1) Small Interfering RNA (siRNA) (3) Trk Receptor (3)
By Research Areas:	Cancer (3) Inflammation/Immunology (2) Metabolic Disease (1) Neurological Disease (11)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P99297

Bedinvetmab ZTS-00508841	Trk Receptor	Inflammation/Immunology
Bedinvetmab (ZTS-00508841) is a canine monoclonal antibody (mAb) targeting nerve growth factor (NGF). Bedinvetmab inhibits NGF interaction with tropomyosin receptor kinase A (trkA) and p75 neurotrophin receptor (p75NTR) receptors. Bedinvetmab can be used for the research of osteoarthritis pain in dogs .

HY-108466

Ro 08-2750 4 Publications Verification	Apoptosis	Neurological Disease Cancer
Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor which binds to NGF, and with an IC₅₀ of ~ 1 μM. Ro 08-2750 inhibits NGF binding to p75 ^NTR selectively over TRKA . Ro 08-2750 is a selective _{MSI RNA-binding} activity inhibitor, with an IC₅₀ of 2.7 μM .

HY-110155

LM11A-31 dihydrochloride Maximum Cited Publications 7 Publications Verification	Neurotensin Receptor	Neurological Disease
LM11A-31 dihydrochloride, a non-peptide *p75 ^NTR* (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist. LM11A-31 dihydrochloride is an amino acid derivative with high blood-brain barrier permeability and blocks p75-mediated cell death. LM11A-31 dihydrochloride reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression .

HY-137322

THX-B	Neurotensin Receptor	Neurological Disease Metabolic Disease
THX-B is a potent and non-peptidic *p75 ^NTR* (neurotrophin receptor p75) antagonist. THX-B can be used in the research of diabetic kidney disease, neurodegenerative and inflammatory disorders .

HY-117088

LM11A-31 Maximum Cited Publications 7 Publications Verification	Neurokinin Receptor	Neurological Disease
LM11A-31, a non-peptide *p75 ^NTR* (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist. LM11A-31 is an amino acid derivative with high blood-brain barrier permeability and blocks p75-mediated cell death. LM11A-31 reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression .

HY-111163

NSC49652	Apoptosis	Cancer
NSC49652 is a reversible, orally active p75 neurotrophin receptor (p75 ^NTR, also known as NGFR, TNFRSF16, and CD271) agonist. NSC49652 targets the transmembrane domain of p75 ^NTR. NSC49652 induces apoptosis and affects the viability of melanoma cells .

HY-110166

PD 90780 2 Publications Verification	Trk Receptor	Neurological Disease
PD 90780 is a non peptide antagonist of nerve growth factor (NGF). PD 90780 interacts with NGF, prevents NGF binds with p75 ^NTR. PD 90780 inhibits NGF-p75 ^NTR interaction with IC₅₀s of 23.1 and 1.8 μM in PC12 cells and PC12 ^nnr5 cells, respectively .

HY-110155A

(Rac)-LM11A-31 dihydrochloride	Drug Isomer	Neurological Disease
(Rac)-LM11A-31 dihydrochloride is an isomer of LM11A-31 dihydrochloride. LM11A-31 dihydrochloride, a non-peptide p75 ^NTR (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist .

HY-170409

BNN27	Trk Receptor Apoptosis	Neurological Disease Inflammation/Immunology
BNN27 is the agonist for TrkA receptor and p75NTR receptor, that exhibits neurotrophic and anti-apoptotic effects. BNN27 increases the levels of glutamate, GABA, and glutamine in the rat hippocampus and prefrontal cortex, improves glutamate turnover. BNN27 exhibits neuroprotective efficacy in mouse amyotrophic lateral sclerosis (ALS) model, exhibits anti-inflammatory efficacy in experimental autoimmune encephalomyelitis (EAE) model, exhibits retinal protective efficacy in rat diabete models. BNN27 is blood-brain barrier penetrable .

HY-P1176

NTR 368	Apoptosis	Neurological Disease
NTR 368 is a peptide derived from p75 neurotrophin receptor (p75NTR) corresponding to residues 368-381 of the human receptor. NTR 368 has helix forming propensity in the presence of micellar lipid. NTR 368 is a potent inducer of neural apoptosis .

HY-P1176A

NTR 368 TFA	Apoptosis	Neurological Disease
NTR 368 TFA is a peptide derived from p75 neurotrophin receptor (p75NTR) corresponding to residues 368-381 of the human receptor. NTR 368 TFA has helix forming propensity in the presence of micellar lipid. NTR 368 TFA is a potent inducer of neural apoptosis .

HY-W370556

(Rac)-LM11A-31	Neurokinin Receptor	Neurological Disease
(Rac)-LM11A-31 is a racemate of LM11A-31. LM11A-31 is a non-peptide modulator of p75NTR (neurotrophin receptor p75) and is an orally effective proNGF antagonist .

HY-108466R

Ro 08-2750 (Standard)	Reference Standards Apoptosis	Neurological Disease Cancer
Ro 08-2750 (Standard) is the analytical standard of Ro 08-2750 (HY-108466). This product is intended for research and analytical applications. Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor which binds to NGF, and with an IC₅₀ of ~ 1 μM. Ro 08-2750 inhibits NGF binding to p75NTR selectively over TRKA . Ro 08-2750 is a selective MSI RNA-binding activity inhibitor, with an IC₅₀ of 2.7 μM .

HY-RS09278

NGFR Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
NGFR Human Pre-designed siRNA Set A contains three designed siRNAs for NGFR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

NGFR Human Pre-designed siRNA Set A NGFR Human Pre-designed siRNA Set A

HY-RS23616

Ngfr Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ngfr Rat Pre-designed siRNA Set A contains three designed siRNAs for Ngfr gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ngfr Rat Pre-designed siRNA Set A Ngfr Rat Pre-designed siRNA Set A

HY-RS17166

Ngfr Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ngfr Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ngfr gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ngfr Mouse Pre-designed siRNA Set A Ngfr Mouse Pre-designed siRNA Set A

Cat. No.	Product Name	Target	Research Area

HY-P1176

NTR 368	Apoptosis	Neurological Disease
NTR 368 is a peptide derived from p75 neurotrophin receptor (p75NTR) corresponding to residues 368-381 of the human receptor. NTR 368 has helix forming propensity in the presence of micellar lipid. NTR 368 is a potent inducer of neural apoptosis .

HY-P1176A

NTR 368 TFA	Apoptosis	Neurological Disease
NTR 368 TFA is a peptide derived from p75 neurotrophin receptor (p75NTR) corresponding to residues 368-381 of the human receptor. NTR 368 TFA has helix forming propensity in the presence of micellar lipid. NTR 368 TFA is a potent inducer of neural apoptosis .

Cat. No.	Product Name	Target	Research Area	Image

HY-P99297

Bedinvetmab ZTS-00508841	Trk Receptor	Inflammation/Immunology
Bedinvetmab (ZTS-00508841) is a canine monoclonal antibody (mAb) targeting nerve growth factor (NGF). Bedinvetmab inhibits NGF interaction with tropomyosin receptor kinase A (trkA) and p75 neurotrophin receptor (p75NTR) receptors. Bedinvetmab can be used for the research of osteoarthritis pain in dogs .

Species:	Human (1) Mouse (2) Rabbit (2)
Tag:	His (2) Fc (3)
Source:	HEK293 (5)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P74699

	NGFR Protein, Rabbit (HEK293, His) NGFR; Gp80-LNGFR; p75 ICD; CD271; TNFRSF16	Rabbit	HEK293
	Nerve Growth Factor Receptor (NGFR) also known as CD271, p75NTR, TNFRSF16, is a transmembrane low-affinity receptor for the neurotrophin family. NGFR has no intrinsic tyrosine kinase activity. NGFR can act as a tumour suppressor, negatively regulating cell growth and proliferation. NGF-NGFR cascade activates NF-κB, leading to inhibition of apoptosis, increases survival of schwannoma, and breast cancer cells. NGFR Protein, Human (HEK293, Fc) is a recombinant protein with a C-Terminal Fc label, It consists of 250 amino acids (M1-N250) and is produced in HEK293 cells. NGFR Protein, Rabbit (HEK293, His) is a recombinant protein with a C-Terminal His label, It consists of 242 amino acids (M1-D242) and is produced in HEK293 cells.

HY-P77100

	NGFR Protein, Mouse (HEK293, Fc) NGFR; Gp80-LNGFR; p75 ICD; CD271; TNFRSF16	Mouse	HEK293
	Nerve Growth Factor Receptor (NGFR) also known as CD271, p75NTR, TNFRSF16, is a transmembrane low-affinity receptor for the neurotrophin family. NGFR has no intrinsic tyrosine kinase activity. NGFR can act as a tumour suppressor, negatively regulating cell growth and proliferation. NGF-NGFR cascade activates NF-κB, leading to inhibition of apoptosis, increases survival of schwannoma, and breast cancer cells. NGFR Protein, Mouse (HEK293, Fc) is a recombinant protein with a C-Terminal Fc label, It consists of 243 amino acids and is produced in HEK293 cells.

HY-P77101

	NGFR Protein, Mouse (HEK293, His) NGFR; Gp80-LNGFR; p75 ICD; CD271; TNFRSF16	Mouse	HEK293
	Nerve Growth Factor Receptor (NGFR) also known as CD271, p75NTR, TNFRSF16, is a transmembrane low-affinity receptor for the neurotrophin family. NGFR has no intrinsic tyrosine kinase activity. NGFR can act as a tumour suppressor, negatively regulating cell growth and proliferation. NGF-NGFR cascade activates NF-κB, leading to inhibition of apoptosis, increases survival of schwannoma, and breast cancer cells. NGFR Protein, Mouse (HEK293, His) is a recombinant protein with a C-Terminal His label, It consists of 243 amino acids (M1-N243) and is produced in HEK293 cells.

HY-P74700

	NGFR Protein, Rabbit (HEK293, hFc) NGFR; Gp80-LNGFR; p75 ICD; CD271; TNFRSF16	Rabbit	HEK293
	Nerve Growth Factor Receptor (NGFR) also known as CD271, p75NTR, TNFRSF16, is a transmembrane low-affinity receptor for the neurotrophin family. NGFR has no intrinsic tyrosine kinase activity. NGFR can act as a tumour suppressor, negatively regulating cell growth and proliferation. NGF-NGFR cascade activates NF-κB, leading to inhibition of apoptosis, increases survival of schwannoma, and breast cancer cells. NGFR Protein, Rabbit (HEK293, hFc) is a recombinant protein with a C-Terminal Fc label, It consists of 242 amino acids (M1-D242) and is produced in HEK293 cells.

HY-P73318

	NGFR Protein, Human (HEK293, Fc) NGFR; Gp80-LNGFR; p75 ICD; CD271; TNFRSF16	Human	HEK293
	Nerve Growth Factor Receptor (NGFR) also known as CD271, p75NTR, TNFRSF16, is a transmembrane low-affinity receptor for the neurotrophin family. NGFR has no intrinsic tyrosine kinase activity. NGFR can act as a tumour suppressor, negatively regulating cell growth and proliferation. NGF-NGFR cascade activates NF-κB, leading to inhibition of apoptosis, increases survival of schwannoma, and breast cancer cells. NGFR Protein, Human (HEK293, Fc) is a recombinant protein with a C-Terminal Fc label, It consists of 250 amino acids (M1-N250) and is produced in HEK293 cells.

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Species
Source
Tag
Accession
Gene ID
Molecular Weight
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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Host:	Mouse (4) Rabbit (5)
Reactivity:	Human (9) Rat (3) Mouse (3)
Application:	IHC-P (7) ICC/IF (5) IF-Tissue (1) IP (2) IHC-F (1) WB (2) FC (4) ELISA (4)
Isotype:	IgG (5) IgG1 (4)
Conjugation:	Non-conjugated (9)
Clonality:	Monoclonal (5) Recombinant (3)
Modification:	Unmodified (5)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P84000

	p75 NGF Receptor Antibody (YA3697) CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR	IHC-P, FC, ELISA	Human
	p75 NGF Receptor Antibody (YA3697) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to p75 NGF Receptor.

HY-P83999

	p75 NGF Receptor Antibody (YA3696) CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR; NGFR	ICC/IF, FC, ELISA	Human
	p75 NGF Receptor Antibody (YA3696) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to p75 NGF Receptor.

HY-P84000A

	p75 NGF Receptor Antibody (YA3697)(PBS only) CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR	IHC-P, FC, ELISA	Human
	p75 NGF Receptor Antibody (YA3697) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to p75 NGF Receptor.

HY-P83999A

	p75 NGF Receptor Antibody (YA3696)(PBS only) CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR; NGFR	ICC/IF, FC, ELISA	Human
	p75 NGF Receptor Antibody (YA3696) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to p75 NGF Receptor.

HY-P83029

	p75 NGF Receptor Antibody (YA2774) CD271 antibody; CD271 antigen antibody; Gp80 LNGFR antibody; Gp80-LNGFR antibody; Low affinity nerve growth factor receptor antibody; Low affinity neurotrophin receptor p75NTR antibody; Low-affinity nerve growth factor receptor antibody; Nerve growth factor receptor antibody; Nerve growth factor receptor TNFR superfamily member 16 antibody; NGF receptor antibody; Ngfr antibody; p75 ICD antibody; p75 Neurotrophin receptor antibody; p75 NTR antibody; p75(NTR) antibody; p75NTR antibody; TNFR Superfamily Member 16 antibody; TNFRSF16 antibody; TNR16_HUMAN antibody; Tumor necrosis factor receptor superfamily member 16 antibody;	WB, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	p75 NGF Receptor Antibody (YA2774) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to p75 NGF Receptor.

HY-P83029A

	p75 NGF Receptor Antibody (YA2774)(PBS only) CD271 antibody; CD271 antigen antibody; Gp80 LNGFR antibody; Gp80-LNGFR antibody; Low affinity nerve growth factor receptor antibody; Low affinity neurotrophin receptor p75NTR antibody; Low-affinity nerve growth factor receptor antibody; Nerve growth factor receptor antibody; Nerve growth factor receptor TNFR superfamily member 16 antibody; NGF receptor antibody; Ngfr antibody; p75 ICD antibody; p75 Neurotrophin receptor antibody; p75 NTR antibody; p75(NTR) antibody; p75NTR antibody; TNFR Superfamily Member 16 antibody; TNFRSF16 antibody; TNR16_HUMAN antibody; Tumor necrosis factor receptor superfamily member 16 antibody;	WB, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	p75 NGF Receptor Antibody (YA2774) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to p75 NGF Receptor.

HY-P85296

	NGFR p75 Antibody (YA4988) NGFR; TNFRSF16; Tumor necrosis factor receptor superfamily member 16; Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD; CD antigen CD271	IHC-P, IHC-F, ICC/IF, IF-Tissue	Human, Rat, Mouse
	NGFR p75 Antibody (YA4988) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to NGFR p75.

HY-P81500

	p75 NGF Receptor Antibody (YA1245) NGFR; TNFRSF16; Tumor necrosis factor receptor superfamily member 16; Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD; CD antigen CD271	IHC-P	Human
	p75 NGF Receptor Antibody (YA1245) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to p75 NGF Receptor.

HY-P81500A

	p75 NGF Receptor Antibody (YA1245)(PBS only) NGFR; TNFRSF16; Tumor necrosis factor receptor superfamily member 16; Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD; CD antigen CD271	IHC-P	Human
	p75 NGF Receptor Antibody (YA1245) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to p75 NGF Receptor.

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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-RS09278

NGFR Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
NGFR Human Pre-designed siRNA Set A contains three designed siRNAs for NGFR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS23616

Ngfr Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Ngfr Rat Pre-designed siRNA Set A contains three designed siRNAs for Ngfr gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS17166

Ngfr Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Ngfr Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ngfr gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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