908563-68-8
908563-68-8
Chemical Structure
NSC49652
- CAS No.: 908563-68-8
- Formula:C14H11NO2
- Molecular Weight:225.24
IUPAC Name: (E)-1-(2-hydroxyphenyl)-3-(pyridin-3-yl)prop-2-en-1-one
InChIKey: CRWNZUBUBIULHB-BQYQJAHWSA-N
SMILES: O=C(C1=CC=CC=C1O)/C=C/C2=CC=CN=C2
Biological Activity: NSC49652 is a reversible, orally active p75 neurotrophin receptor (p75NTR, also known as NGFR, TNFRSF16, and CD271) agonist. NSC49652 targets the transmembrane domain of p75NTR. NSC49652 induces apoptosis and affects the viability of melanoma cells[1].
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NSC49652 | 98.74% | NSC49652 is a reversible, orally active p75 neurotrophin receptor (p75NTR, also known as NGFR, TNFRSF16, and CD271) agonist. NSC49652 targets the transmembrane domain of p75NTR. NSC49652 induces apoptosis and affects the viability of melanoma cells. | ||||||||||||||||||||
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References
Keywords
