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Cat. No.: HY-111163R

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NSC49652 (Standard)

NSC49652 (Standard) is the analytical standard of NSC49652 (HY-111163). This product is intended for research and analytical applications. NSC49652 is a reversible, orally active p75 neurotrophin receptor (p75NTR, also known as NGFR, TNFRSF16, and CD271) agonist. NSC49652 targets the transmembrane domain of p75NTR. NSC49652 induces apoptosis and affects the viability of melanoma cells.

For research use only. We do not sell to patients.

CAS No.: 908563-68-8
Formula: C₁₄H₁₁NO₂
Molecular Weight:225.25

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

NSC49652 (Standard) Chemical Structure

CAS No.: 908563-68-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 908563-68-8
Molecular Weight 225.25
Formula C₁₄H₁₁NO₂
SMILES

O=C(C1=CC=CC=C1O)/C=C/C2=CC=CN=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Goh ETH, et al. A Small Molecule Targeting the Transmembrane Domain of Death Receptor p75NTR Induces Melanoma Cell Death and Reduces Tumor Growth. Cell Chem Biol. 2018 Dec 20;25(12):1485-1494.e5. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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