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Results for "

phenol groups

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (1) Biochemical Assay Reagents (11) Cannabinoid Receptor (1) Drug Derivative (1) Drug Intermediate (1) Drug Metabolite (4) Endogenous Metabolite (2) Fluorescent Dye (3) Isotope-Labeled Compounds (1) Lipase (1) PDI (1) Phosphatase (1) PROTAC Linkers (1) Reference Standards (5) Tyrosinase (2) UGT (1)
By Research Areas:	Cancer (4) Infection (1) Inflammation/Immunology (7) Metabolic Disease (2)
Click Chemistry:	Labeling and Fluorescence Imaging (2) PROTAC Synthesis (1) Azide (2) Alkynes (1)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-131442

Alkyne-phenol 3 Publications Verification Alkyne tyramide; Alk-Ph	Biochemical Assay Reagents	Others
Alkyne-phenol (Alk-Ph) is a clickable ascorbate peroxidase 2 (APEX2) probe. Alkyne-phenol substantially improves APEX-labeling efficiency in intact yeast cells, as it is more cell wall-permeant than APEX2 substrate biotin-phenol (BP). Alkyne-phenol also facilitates the identification of APEX-labeling sites, allowing the unambiguous assignment of membrane topology of mitochondrial proteins . Alkyne-phenol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W127711

Fast Blue B Salt, Dye content ~95%	Phosphatase Lipase	Metabolic Disease Inflammation/Immunology
Fast Blue B Salt, Dye content ~95% is a diazo dye, primarily used as a chromogenic substrate in biochemical analysis. Fast Blue B Salt, Dye content ~95% is the coupling agent for the histochemical demonstration of proteases. Fast Blue B Salt, Dye content ~95% can be used for the detection of acid phosphatase in Clostridium perfringens, and also for the determination of lipase activity. Fast Blue B Salt, Dye content ~95% reacts directly with the active hydroxyl groups in phenolic compounds to determine the content of phenolic substances .

HY-Y0801

2,6-Dihydroxybenzoic acid	Drug Metabolite	Others
2,6-Dihydroxybenzoic acid is an aromatic compound containing phenolic hydroxyl groups and carboxyl groups, and it is a secondary metabolite of Salicylic acid (HY-B0167). 2,6-Dihydroxybenzoic acid is also present in olive oil wastewater .

HY-119323

7-Azido-4-methylcoumarin 1 Publications Verification	Fluorescent Dye	Others
7-Azido-4-methylcoumarin is a selective coumarin-based fluorescent probe for hydrogen sulfide (H₂S). In the presence of H₂S, the aromatic azido group of 7-Azido-4-methylcoumarin is selectively reduced to produce the fluorescently active 7-amino-4-methylcoumarin (AMC). 7-Azido-4-methylcoumarin binds to the coumarin/phenol-binding site of BSA, the aglycone-binding site of UGT1A6, and the substrate-binding site of SULT1A1, respectively. 7-Azido-4-methylcoumarin retains its fluorescent properties after covalent binding, acts as a fluorescent H₂S probe, and does not react with cysteine, homocysteine or glutathione (Ex/Em = 340/445 nm) .

HY-N6654

Syringyl Alcohol 1 Publications Verification Syringic Alcohol	Drug Derivative	Others
Syringyl Alcohol (Syringic Alcohol) is a derivate of phenol comprises both phenolic and alcoholic functional groups. Syringyl Alcohol is a probe molecule for the evaluation of the catalytic performance of various carbonaceous nanomaterials (CNMs) .

HY-W022036

2-Ethoxyphenol Guaethol; Guethol; NSC 180	Biochemical Assay Reagents	Others
2-Ethoxyphenol, also known as guaiacol ethyl ether, consists of a phenolic ring and an ethoxy group connected to the 2-position. The compound has a sweet, smoky flavor and is commonly used as a flavoring in foods such as baked goods, candy and beverages.

HY-128835

Phenol-amido-C1-PEG3-N3 PROTAC Linker 21	PROTAC Linkers	Cancer
Phenol-amido-C1-PEG3-N3 (PROTAC Linker 21) is an PEG-based PROTAC linker can be used in the synthesis of PROTACs . Phenol-amido-C1-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-G0004

Acetaminophen metabolite 3-hydroxy-acetaminophen 3-Hydroxyacetaminophen	Drug Metabolite	Inflammation/Immunology
Acetaminophen metabolite 3-hydroxy-acetaminophen (3-Hydroxyacetaminophen) is a non-toxic metabolite and antioxidant of acetaminophen (HY-66005) with free radical scavenging activity. Acetaminophen metabolite 3-hydroxy-acetaminophen can reduce oxidative damage by exerting electron donation ability and antioxidant activity through phenolic hydroxyl groups. 3-hydroxy-acetaminophen can be used to study the toxicity mechanism and drug metabolism of acetaminophen .

HY-116772

Cyanox CY 1790 Irganox 1790	Biochemical Assay Reagents	Others
Cyanox CY 1790 (Irganox 1790) is a synthetic phenolic antioxidant. Cyanox CY 1790 is mainly used to protect polyolefin materials such as polypropylene and polyethylene from thermo-oxidative degradation during processing (high temperature) and service .

HY-Y1374

Benzoic anhydride	Biochemical Assay Reagents	Others
Benzoic anhydride is a catalyst that can be used for organic synthesis reactions. Benzoic anhydride is used as a chemical titration reagent for selective quantification and deactivation of phenolic hydroxyl groups on the surface of carbon nanotubes .

HY-W017092

1,2,3-Trimethoxybenzene	Drug Intermediate	Others
1,2,3-Trimethoxybenzene is a model compound of lignin. 1,2,3-Trimethoxybenzene can potentially serve as a biomarker for certain foods due to its presence in tea. 1,2,3-Trimethoxybenzene can be used as a drug intermediate for synthesizing 2,6-dimethoxy-1,4-benzoquinone (HY-N1677) .

HY-W007671

H-Tyr-OMe 1 Publications Verification	Endogenous Metabolite Tyrosinase	Others
H-Tyr-OMe is an endogenous metabolite. H-Tyr-OMe quenches the fluorescence of carbon dots by oxidizing the phenolic hydroxyl group to quinone under the catalysis of Tyrosinase, and its amino and thiol binding ability can respond to changes in the concentration of biothiols .

HY-150175

HKSOX-1	Fluorescent Dye	Inflammation/Immunology
HKSOX-1 and its derivatives (HKSOX-1r and HKSOX-1m) are novel fluorescent probes designed for highly sensitive and selective detection of the superoxide anion radical (O₂ ^•−) in cellular environments. These probes utilize an aryl trifluoromethanesulfonate group that undergoes O₂ ^•−-mediated cleavage, releasing a free phenol and emitting fluorescence. They demonstrate excellent specificity and sensitivity across various pH ranges, withstand interference from strong oxidants and reductants typical in cellular contexts. HKSOX-1r, optimized for cellular retention, has been effectively employed in diverse assays including confocal imaging, flow cytometry, and zebrafish embryo studies, highlighting its utility in investigating O₂ ^•− roles in inflammation, mitochondrial stress, and other physiological processes .

HY-W010221

Phenyltrimethylammonium hydroxide Trimethylanilinium hydroxide (ca. 8.5% in Methanol)	Biochemical Assay Reagents	Others
Phenyltrimethylammonium hydroxide (Trimethylanilinium hydroxide (ca. 8.5% in Methanol)) is a derivatization reagent. Phenyltrimethylammonium hydroxide converts phenolic compounds including pentachlorophenol herbicides into methyl ethers .

HY-A0108S

Trimethyl phosphate-d9	Isotope-Labeled Compounds	Others
Trimethyl phosphate-d₉ is the deuterium labeled Trimethyl phosphate (HY-A0108A). Trimethyl phosphate is a methylating agent. Trimethyl phosphate transfers methyl groups to aliphatic alcohols, phenols, and amines .

HY-A0108AR

Trimethyl phosphate (Standard)	Reference Standards	Others
Trimethyl phosphate (Standard) is the analytical standard of Trimethyl phosphate (HY-A0108A). This product is intended for research and analytical applications. Trimethyl phosphate is a methylating agent. Trimethyl phosphate transfers methyl groups to aliphatic alcohols, phenols, and amines .

HY-W007671R

H-Tyr-OMe (Standard)	Reference Standards Endogenous Metabolite Tyrosinase	Others
H-Tyr-OMe is an endogenous metabolite. H-Tyr-OMe quenches the fluorescence of carbon dots by oxidizing the phenolic hydroxyl group to quinone under the catalysis of Tyrosinase, and its amino and thiol binding ability can respond to changes in the concentration of biothiols .

HY-Y0801R

2,6-Dihydroxybenzoic acid (Standard)	Reference Standards Drug Metabolite	Others
2,6-Dihydroxybenzoic acid (Standard) is the analytical standard of 2,6-Dihydroxybenzoic acid (HY-Y0801). This product is used for research and analytical applications. 2,6-Dihydroxybenzoic acid is an aromatic compound containing phenolic hydroxyl groups and carboxyl groups, and it is a secondary metabolite of Salicylic acid (HY-B0167). 2,6-Dihydroxybenzoic acid is also present in olive oil wastewater .

HY-121011

Cannabigerorcin	Cannabinoid Receptor
Cannabigerorcin is a phenolic compound found in cannabis plants, featuring a diphenol backbone and a terpene side chain. By reacting with radiolabeled methylmagnesium carbonate (MMC), its carboxyl group can be ¹⁴C-labeled. Radiolabeled Cannabigerorcin is widely used in research on cannabinoid biosynthesis pathways and metabolic processes .

HY-Y1374R

Benzoic anhydride (Standard)	Biochemical Assay Reagents Reference Standards	Others
Benzoic anhydride (Standard) is the analytical standard of Benzoic anhydride. This product is intended for research and analytical applications. Benzoic anhydride is a catalyst that can be used for organic synthesis reactions. Benzoic anhydride is used as a chemical titration reagent for selective quantification and deactivation of phenolic hydroxyl groups on the surface of carbon nanotubes .

HY-164055

HL1	Fluorescent Dye	Cancer
HL1 is a Schiff base ligand. HL1 exhibits chelation-enhanced fluorescence effect when forming complexes and can be used as a fluorescent probe for metal ions. HL1 can be used for the research of cancer .

HY-G0004R

Acetaminophen metabolite 3-hydroxy-acetaminophen (Standard) 3-Hydroxyacetaminophen (Standard)	Reference Standards Drug Metabolite	Inflammation/Immunology
Acetaminophen metabolite 3-hydroxy-acetaminophen (3-Hydroxyacetaminophen) (Standard) is the analytical standard of Acetaminophen metabolite 3-hydroxy-acetaminophen (HY-G0004). This product is intended for research and analytical applications. Acetaminophen metabolite 3-hydroxy-acetaminophen is a non-toxic metabolite and antioxidant of acetaminophen (HY-66005) with free radical scavenging activity. Acetaminophen metabolite 3-hydroxy-acetaminophen can reduce oxidative damage by exerting electron donation ability and antioxidant activity through phenolic hydroxyl groups. 3-hydroxy-acetaminophen can be used to study the toxicity mechanism and drug metabolism of acetaminophen .

HY-114735

Mandelonitrile benzoate	Antibiotic	Infection
Mandelonitrile benzoate is a defensive secretion of millipedes that releases other chemicals during the cyanidation process in addition to hydrocyanic acid (HCN) and benzaldehyde. Several families of millipedes, including Polydesmidae, Paradoxosomatidae, and Euryuridae, have been shown to secrete phenols and guaiaeol, with one Paradoxosomatid also producing ethylbenzoic acid and benzoic acid. In addition, members of the Xystodesmidae family commonly produce three compounds: benzoic acid, mandelonitrile benzoate, and benzoyl cyanide. Benzoyl cyanide has not been previously discovered as a natural product. These additional natural products are discussed as defensive antipredator and antibiotic agents. Benzoyl cyanide appears to have anesthetic properties for some predators. The study provides a preliminary chemotaxonomic basis for distinguishing various taxonomic groups of millipedes.

HY-N15727

2,5-Dimethylchromone-7-O-β-D-glucopyranoside	Others	Inflammation/Immunology
2,5-Dimethylchromone-7-O-β-D-glucopyranoside is an orally active chromone glycoside found in the underground parts of Rheum australe. 2,5-Dimethylchromone-7-O-β-D-glucopyranoside shows a DPPH radical scavenging activity with an IC₅₀ value of 66.9 μM. 2,5-Dimethylchromone-7-O-β-D-glucopyranoside scavenges free radicals by providing hydrogen atoms through phenolic hydroxyl groups, inhibiting lipid peroxidation. 2,5-Dimethylchromone-7-O-β-D-glucopyranoside is promising for research of oxidative stress-related diseases such as inflammation and skin diseases .

HY-W140502

4-Hexadecylphenol	Biochemical Assay Reagents	Others
4-Hexadecylphenol is a phenol group with a 16-carbon tail.

HY-W413662

4-((4-Methoxybenzyl)oxy)butan-1-ol	Biochemical Assay Reagents	Others
4-[(4-Methoxyphenyl)methoxy]butan-1-ol is a compound with a methyl phenol group and a butanol tail. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

HY-W598194

1-((4-Azidobutoxy)methyl)-4-methoxybenzene	Biochemical Assay Reagents	Others
1-((4-Azidobutoxy)methyl)-4-methoxybenzene is a compound with a methyl phenol group and a butyl tail ending in a terminal azide. The azide (N3) group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.

HY-W015811

3-N-Propylphenol	PDI	Metabolic Disease Inflammation/Immunology Cancer
3-N-Propylphenol is a small phenolic derivative containing a hydroxyl aryl group that competitively inhibits the binding of the peptide to pancreatic-specific protein disulfide isomerase (PDIp). 3-Propylphenol can be used for research on pancreatic-related diseases .

HY-W006081

3-Methyl-2-nitrophenol	UGT	Others
3-Methyl-2-nitrophenol is a UDP-glucuronyltransferase (EC 2.4.1.17) acceptor substrate that can be confirmed to undergo glucuronidation catalyzed by the enzyme to form a glucuronide conjugate. 3-Methyl-2-nitrophenol functions as a substrate for conjugation, with glucuronidation forming a glucuronide conjugate that eliminates the parent compound’s characteristic yellow color. 3-Methyl-2-nitrophenol has higher lipid solubility that contributes to high glucuronidation conversion rate, and exhibits lower absorbance at 340 nm to act as a less interfering substrate for the NADH-NAD ⁺-linked UDP-glucuronyltransferase assay .

HY-E71131

(S)-Stylopine synthase	Biochemical Assay Reagents	Others
(S)-Stylopine synthase (EC 1.14.21.1) catalyzes an oxidation reaction that does not introduce oxygen into the product. (S)-Stylopine synthase (EC 1.14.21.1) forms a second methylenedioxy bridge in the protoberberine alkaloid stylopine by oxidatively cyclizing cheilanthifoline with adjacent phenolic hydroxyl and methoxy groups.

HY-E71128

(S)-Nandinine synthase	Biochemical Assay Reagents	Others
(S)-Nandinine synthase (EC 1.14.21.12) is a cytochrome P-450 heme-thiolate enzyme catalysing an oxidative reaction that does not incorporate oxygen into the product. Forms the methylenedioxy bridge of the protoberberine alkaloid (S)-Nandinine by the oxidative ring closure of adjacent phenolic and methoxy groups of (S)-Scoulerine.

HY-N17138

threo-1-(4-Hydroxyphenyl)-1-methoxy-2,3-propanediol	Others	Inflammation/Immunology Cancer
threo-1-(4-Hydroxyphenyl)-1-methoxy-2,3-propanediol is an aromatic propanediol phenolic derivative containing methoxy and hydroxyl groups. It can be naturally extracted from the dried aerial parts of Abies delavayi Franch. var. delavayi (Cangshan fir) from Dali, Yunnan, China. This source plant produces anti-inflammatory and anti-tumor active components .

Cat. No.	Product Name

HY-L057

Phenols Library	1,290 compounds
Phenolic compounds are usually referred to as a diverse group of naturally occurring compounds with multiple medical properties, such as antioxidants, antimicrobial properties. Those compounds are commonly found in food and plants. They have high synthetic, medicinal and industrial values. Polyphenols are compounds with multiple phenolic functionalities. Naturally occurring polyphenols are known to have biological activities for use as drugs, for example, in diseases like AIDS, heart ailments, ulcer formation, bacterial infection, mutagenesis and neural disorders. MCE offers a unique collection of 1,290 natural phenol compounds which is a useful tool for drug discovery as an important source of lead compounds.

Phenols Library

1,290 compounds

Phenolic compounds are usually referred to as a diverse group of naturally occurring compounds with multiple medical properties, such as antioxidants, antimicrobial properties. Those compounds are commonly found in food and plants. They have high synthetic, medicinal and industrial values. Polyphenols are compounds with multiple phenolic functionalities. Naturally occurring polyphenols are known to have biological activities for use as drugs, for example, in diseases like AIDS, heart ailments, ulcer formation, bacterial infection, mutagenesis and neural disorders.

MCE offers a unique collection of 1,290 natural phenol compounds which is a useful tool for drug discovery as an important source of lead compounds.

HY-L924

Boronic acid/boronic ester fragment library	1,488 compounds
Boronic acid and boronic ester represent a relatively novel and promising chemical structure in drug design. Boronic acid exists in an sp²-hybridized state, possessing an empty p-orbital that can act as a Lewis acid to accept lone pairs from heteroatoms (O, N, or S). This Lewis acidity enables it to form reversible covalent bonds with amino acid residues such as lysine, serine, threonine, and histidine. Currently, five FDA-approved drugs containing boronic acid or boronic ester predominantly involve such covalent binding mechanisms in their interactions with target proteins. Furthermore, boronic acid can serve as a bioisostere for carboxylic acids, phosphates, and phenolic groups, utilized to improve pharmacokinetic properties and enhance drug efficacy. To date, five boron-containing drugs have been approved by the FDA. The unique properties of boronic acids and boronic esters confer significant potential in drug design, with applications spanning cancer therapy (e.g., multiple myeloma), anti-infectives (e.g., fungal infections, tuberculosis), anti-inflammatory treatments (e.g., atopic dermatitis), antibacterial agents (e.g., carbapenem-resistant bacterial infections), and Reactive Oxygen Species (ROS)-responsive prodrugs, among others. The MCE Boronic Acid/Boronic Ester Fragment Library, which contains 1,488 compounds, serves as a valuable tool for the development of boron-containing drugs.

Boronic acid/boronic ester fragment library

1,488 compounds

Boronic acid and boronic ester represent a relatively novel and promising chemical structure in drug design. Boronic acid exists in an sp²-hybridized state, possessing an empty p-orbital that can act as a Lewis acid to accept lone pairs from heteroatoms (O, N, or S). This Lewis acidity enables it to form reversible covalent bonds with amino acid residues such as lysine, serine, threonine, and histidine. Currently, five FDA-approved drugs containing boronic acid or boronic ester predominantly involve such covalent binding mechanisms in their interactions with target proteins. Furthermore, boronic acid can serve as a bioisostere for carboxylic acids, phosphates, and phenolic groups, utilized to improve pharmacokinetic properties and enhance drug efficacy.

To date, five boron-containing drugs have been approved by the FDA. The unique properties of boronic acids and boronic esters confer significant potential in drug design, with applications spanning cancer therapy (e.g., multiple myeloma), anti-infectives (e.g., fungal infections, tuberculosis), anti-inflammatory treatments (e.g., atopic dermatitis), antibacterial agents (e.g., carbapenem-resistant bacterial infections), and Reactive Oxygen Species (ROS)-responsive prodrugs, among others. The MCE Boronic Acid/Boronic Ester Fragment Library, which contains 1,488 compounds, serves as a valuable tool for the development of boron-containing drugs.

Cat. No.	Product Name	Type

HY-W127711

Fast Blue B Salt, Dye content ~95%	Fluorescent Dye
Fast Blue B Salt, Dye content ~95% is a diazo dye, primarily used as a chromogenic substrate in biochemical analysis. Fast Blue B Salt, Dye content ~95% is the coupling agent for the histochemical demonstration of proteases. Fast Blue B Salt, Dye content ~95% can be used for the detection of acid phosphatase in Clostridium perfringens, and also for the determination of lipase activity. Fast Blue B Salt, Dye content ~95% reacts directly with the active hydroxyl groups in phenolic compounds to determine the content of phenolic substances .

Fast Blue B Salt, Dye content ~95%

Fluorescent Dye

Fast Blue B Salt, Dye content ~95% is a diazo dye, primarily used as a chromogenic substrate in biochemical analysis. Fast Blue B Salt, Dye content ~95% is the coupling agent for the histochemical demonstration of proteases. Fast Blue B Salt, Dye content ~95% can be used for the detection of acid phosphatase in Clostridium perfringens, and also for the determination of lipase activity. Fast Blue B Salt, Dye content ~95% reacts directly with the active hydroxyl groups in phenolic compounds to determine the content of phenolic substances .

Cat. No.	Product Name	Type

HY-W127711

Fast Blue B Salt, Dye content ~95%	Biochemical Assay Reagents
Fast Blue B Salt, Dye content ~95% is a diazo dye, primarily used as a chromogenic substrate in biochemical analysis. Fast Blue B Salt, Dye content ~95% is the coupling agent for the histochemical demonstration of proteases. Fast Blue B Salt, Dye content ~95% can be used for the detection of acid phosphatase in Clostridium perfringens, and also for the determination of lipase activity. Fast Blue B Salt, Dye content ~95% reacts directly with the active hydroxyl groups in phenolic compounds to determine the content of phenolic substances .

Fast Blue B Salt, Dye content ~95%

Biochemical Assay Reagents

HY-W022036

2-Ethoxyphenol Guaethol; Guethol; NSC 180	Biochemical Assay Reagents
2-Ethoxyphenol, also known as guaiacol ethyl ether, consists of a phenolic ring and an ethoxy group connected to the 2-position. The compound has a sweet, smoky flavor and is commonly used as a flavoring in foods such as baked goods, candy and beverages.

HY-W010221

Phenyltrimethylammonium hydroxide Trimethylanilinium hydroxide (ca. 8.5% in Methanol)	Biochemical Assay Reagents
Phenyltrimethylammonium hydroxide (Trimethylanilinium hydroxide (ca. 8.5% in Methanol)) is a derivatization reagent. Phenyltrimethylammonium hydroxide converts phenolic compounds including pentachlorophenol herbicides into methyl ethers .

HY-A0108AR

Trimethyl phosphate (Standard)	Biochemical Assay Reagents
Trimethyl phosphate (Standard) is the analytical standard of Trimethyl phosphate (HY-A0108A). This product is intended for research and analytical applications. Trimethyl phosphate is a methylating agent. Trimethyl phosphate transfers methyl groups to aliphatic alcohols, phenols, and amines .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-Y0801

2,6-Dihydroxybenzoic acid	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Phenols Polyphenols Endogenous metabolite Disease Research Fields Source Classification	Drug Metabolite
2,6-Dihydroxybenzoic acid is an aromatic compound containing phenolic hydroxyl groups and carboxyl groups, and it is a secondary metabolite of Salicylic acid (HY-B0167). 2,6-Dihydroxybenzoic acid is also present in olive oil wastewater .

HY-W007671

H-Tyr-OMe 1 Publications Verification	Monophenols Classification of Application Fields Other Diseases Phenols Amino acids Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Tyrosinase
H-Tyr-OMe is an endogenous metabolite. H-Tyr-OMe quenches the fluorescence of carbon dots by oxidizing the phenolic hydroxyl group to quinone under the catalysis of Tyrosinase, and its amino and thiol binding ability can respond to changes in the concentration of biothiols .

HY-W007671R

H-Tyr-OMe (Standard)	Monophenols Phenols Amino acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Tyrosinase
H-Tyr-OMe is an endogenous metabolite. H-Tyr-OMe quenches the fluorescence of carbon dots by oxidizing the phenolic hydroxyl group to quinone under the catalysis of Tyrosinase, and its amino and thiol binding ability can respond to changes in the concentration of biothiols .

HY-Y0801R

2,6-Dihydroxybenzoic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Phenols Polyphenols Endogenous metabolite Source Classification	Reference Standards Drug Metabolite
2,6-Dihydroxybenzoic acid (Standard) is the analytical standard of 2,6-Dihydroxybenzoic acid (HY-Y0801). This product is used for research and analytical applications. 2,6-Dihydroxybenzoic acid is an aromatic compound containing phenolic hydroxyl groups and carboxyl groups, and it is a secondary metabolite of Salicylic acid (HY-B0167). 2,6-Dihydroxybenzoic acid is also present in olive oil wastewater .

HY-N15727

2,5-Dimethylchromone-7-O-β-D-glucopyranoside	Rheum australe D. Don Polygonaceae Plants Saccharides Monosaccharides Source Classification	Others
2,5-Dimethylchromone-7-O-β-D-glucopyranoside is an orally active chromone glycoside found in the underground parts of Rheum australe. 2,5-Dimethylchromone-7-O-β-D-glucopyranoside shows a DPPH radical scavenging activity with an IC₅₀ value of 66.9 μM. 2,5-Dimethylchromone-7-O-β-D-glucopyranoside scavenges free radicals by providing hydrogen atoms through phenolic hydroxyl groups, inhibiting lipid peroxidation. 2,5-Dimethylchromone-7-O-β-D-glucopyranoside is promising for research of oxidative stress-related diseases such as inflammation and skin diseases .

HY-N17138

threo-1-(4-Hydroxyphenyl)-1-methoxy-2,3-propanediol	Structural Classification Monophenols Pinaceae Abies delavayi Franch. Phenols Plants Source Classification	Others
threo-1-(4-Hydroxyphenyl)-1-methoxy-2,3-propanediol is an aromatic propanediol phenolic derivative containing methoxy and hydroxyl groups. It can be naturally extracted from the dried aerial parts of Abies delavayi Franch. var. delavayi (Cangshan fir) from Dali, Yunnan, China. This source plant produces anti-inflammatory and anti-tumor active components .

Cat. No.	Product Name	Chemical Structure

HY-A0108S

Trimethyl phosphate-d9
Trimethyl phosphate-d₉ is the deuterium labeled Trimethyl phosphate (HY-A0108A). Trimethyl phosphate is a methylating agent. Trimethyl phosphate transfers methyl groups to aliphatic alcohols, phenols, and amines .

Cat. No.	Product Name		Classification

HY-131442

Alkyne-phenol 3 Publications Verification Alkyne tyramide; Alk-Ph		Labeling and Fluorescence Imaging Alkynes
Alkyne-phenol (Alk-Ph) is a clickable ascorbate peroxidase 2 (APEX2) probe. Alkyne-phenol substantially improves APEX-labeling efficiency in intact yeast cells, as it is more cell wall-permeant than APEX2 substrate biotin-phenol (BP). Alkyne-phenol also facilitates the identification of APEX-labeling sites, allowing the unambiguous assignment of membrane topology of mitochondrial proteins . Alkyne-phenol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-119323

7-Azido-4-methylcoumarin 1 Publications Verification		Azide Labeling and Fluorescence Imaging
7-Azido-4-methylcoumarin is a selective coumarin-based fluorescent probe for hydrogen sulfide (H₂S). In the presence of H₂S, the aromatic azido group of 7-Azido-4-methylcoumarin is selectively reduced to produce the fluorescently active 7-amino-4-methylcoumarin (AMC). 7-Azido-4-methylcoumarin binds to the coumarin/phenol-binding site of BSA, the aglycone-binding site of UGT1A6, and the substrate-binding site of SULT1A1, respectively. 7-Azido-4-methylcoumarin retains its fluorescent properties after covalent binding, acts as a fluorescent H₂S probe, and does not react with cysteine, homocysteine or glutathione (Ex/Em = 340/445 nm) .

HY-128835

Phenol-amido-C1-PEG3-N3 PROTAC Linker 21		Azide PROTAC Synthesis
Phenol-amido-C1-PEG3-N3 (PROTAC Linker 21) is an PEG-based PROTAC linker can be used in the synthesis of PROTACs . Phenol-amido-C1-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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