1694495-59-4
Chemical Structure
Alkyne-phenol
Synonym(s): Alkyne tyramide; Alk-Ph
- CAS No.: 1694495-59-4
- Formula:C13H15NO2
- Molecular Weight:217.26
IUPAC Name: N-(4-hydroxyphenethyl)pent-4-ynamide
InChIKey: CQZJBJSXQYZLEX-UHFFFAOYSA-N
SMILES: C#CCCC(NCCC1=CC=C(O)C=C1)=O
Biological Activity: Alkyne-phenol (Alk-Ph) is a clickable ascorbate peroxidase 2 (APEX2) probe. Alkyne-phenol substantially improves APEX-labeling efficiency in intact yeast cells, as it is more cell wall-permeant than APEX2 substrate biotin-phenol (BP). Alkyne-phenol also facilitates the identification of APEX-labeling sites, allowing the unambiguous assignment of membrane topology of mitochondrial proteins[1]. Alkyne-phenol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Alkyne-phenol | 99.72% | Alkyne-phenol (Alk-Ph) is a clickable ascorbate peroxidase 2 (APEX2) probe. Alkyne-phenol substantially improves APEX-labeling efficiency in intact yeast cells, as it is more cell wall-permeant than APEX2 substrate biotin-phenol (BP). Alkyne-phenol also facilitates the identification of APEX-labeling sites, allowing the unambiguous assignment of membrane topology of mitochondrial proteins. Alkyne-phenol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 0.92
HY-155639Tyramide alkyne -
Similarity Score 0.75
HY-1720104-Hydroxyphenylpropionylglycine -
Similarity Score 0.72
HY-136537AN-β-alanyldopamine hydrochloride -
Similarity Score 0.70
HY-169751Dihydro-N-caffeoyltyramine -
Similarity Score 0.69
HY-W179151N-Octanoyl dopamine -
Similarity Score 0.68
HY-138210N,O-Diacetyltyramine -
Similarity Score 0.67
HY-N0113AHordenine sulfate -
Similarity Score 0.67
HY-N17646N-trans-Cinnamoyltyramine -
Similarity Score 0.67
HY-180756p-Coumaroylputrescine -
Explore the MedChemAI to find more analogs
