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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
30 Results for "
photo-activatable
" in MedChemExpress (MCE) Product Catalog:
Products (30)
30 Results for "photo-activatable" in MCE Product Catalog:
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ANB-NOS is a heterobifunctional crosslinker with lipophilic, uncharged properties suitable for intracellular conjugation. ANB-NOS contains an amine-reactive Nhydroxysuccinimide (NHS) ester and a photoactivatable nitrophenyl azide. ANB-NOS can be used for the research of fibrosarcoma and mammary adenocarcinoma .
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NVOC cage-TMP-Halo is a cell-permeable and photoactivatable protein dimerization inducer. NVOC cage-TMP-Halo can rapidly and reversibly control protein localization in living cells. NVOC cage-TMP-Halo can be used for dynamic cellular processes research .
Cat. No.: HY-176548
CAS No.: 2765218-57-1
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PY-PAP is a photoactivatable affinity probe and a derivative of PY-60 (HY-141644). PY-PAP retains the cellular function of activating YAP transcriptional activity. In 293A cells, PY-PAP can label cathepsin D (CTSD) and annexin A2 (ANXA2) through ultraviolet crosslinking and click reactions. PY-PAP plays a key role in identifying ANXA2 as the specific target of PY-60 .
Cat. No.: HY-D2923
CAS No.: 1811539-43-1
Cat. No.: HY-131025
CAS No.: 1811539-88-4
Synonyms: JF585, SE; JF585, NHS
Cat. No.: HY-W895359
CAS No.: 2707485-30-9
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Photoclick myristic acid is a derivative of Myristic acid (HY-N2041) with an alkyne group and a photo-activatable diazirine group. Photoclick myristic acid can be used as a probe in protein research .
Cat. No.: HY-178152
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RuOPt is a photoactivatable Ru(II)-Pt(IV) complex with reduced dark toxicity. Under irradiation, RuOPt induces apoptosis, generates ROS, and inhibits tumor spheroid growth, demonstrating comparable phototoxicity .
Cat. No.: HY-145323
CAS No.: 2883123-79-1
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Mitochondria-Targeted Photoactivatable Proagent accumulates in the mitochondria and shows light-triggered temporally controlled cell death. Mitochondria-Targeted Photoactivatable Proagent can be used in a novel drug delivery platform that provides on-demand, real-time, organelle-specific agent release and monitoring upon photoactivation .
Cat. No.: HY-134976
CAS No.: 881914-35-8
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Azido-FTY720 is a photoactivatable analogue of FTY720. Azido-FTY720 is used for identifying binding sites between FTY720 and its receptors . Azido-FTY720 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-168497
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C-MS023 is a photo-activatable MS023 (HY-19615) prodrug, achieving spatiotemporal inhibition of Histone Arginine Asymmetric Dimethylation. C-MS023 inhibits PRMT6 mediated asymmetric dimethylation of H3 arginine 2 (H3R2me2a), with an estimate IC50 of 0.2224 μM. The photolysis of C-MS023 could be triggered by visible light irradiation at 420 nm, thereby liberating MS023 for effective downregulation of histone arginine asymmetric dimethylation and DNA replication-related transcriptomic activities .
Cat. No.: HY-176725
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ZnPcPs is a photosensitizer that generates ROS. ZnPcPs can be used to synthesize the photo-activated BRD4 degrader pZnPc-O3-JQ1 (HY-176724) .
Cat. No.: HY-133534
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PA-Nic TFA is a photoactivatable nicotine, whcih can be photolyzed with ~405 nm laser flashes to efficiently release nicotine .
Cat. No.: HY-125600
CAS No.: 156281-08-2
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LY219703 is a photoactivatable analogue of the antitumor diarylsulfonylurea sulofenur. LY219703 are distributed mainly in membranes, particularly those of organelles such as mitochondria .
Cat. No.: HY-170220
CAS No.: 1262788-58-8
Cat. No.: HY-W800683
CAS No.: 220446-74-2
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4-Azide-TFP-Amide-SS-Sulfo-NHS consists of an aryl azide, a cleavable disulfide bond, and an NHS ester. The aryl azide can be photo-activated with UV light (250 to 350 nm) for conjugation with biomolecules. Fluoro helps to stabilize the free radical intermediate. The NHS ester reacts with amines. The disulfide bond can be cleaved by reducing agents.
Cat. No.: HY-157880
Synonyms: Azido-PC
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N3-PC (Azido-PC) is a photoactivatable phosphatidylcholine that can be used in the synthesis of cell membrane structures. N3-PC (Azido-PC) is a click chemistry reagent containing an azide group .
Cat. No.: HY-176726
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ZnPc-amide-PEG3-C2-NH2 is a photosensitizer-linker conjugate which consists of ZnPcPs (HY-176725) and a linker (HY-W040165). ZnPc-amide-PEG3-C2-NH2 can be used to synthesize the photo-activated BRD4 degrader pZnPc-O3-JQ1 (HY-176724) .
Cat. No.: HY-184364
CAS No.: 2989205-54-9
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Photoclick stearic acid is a bifunctional lipid probe derived from stearic acid, containing a photo-activatable diazirine group and a terminal clickable alkyne moiety. Photoclick stearic acid can be used as a chemical reporter to investigate protein lipidation and analyze membrane protein-protein interactions .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
