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Cat. No.: HY-178152

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RuOPt

RuOPt is a photoactivatable Ru(II)-Pt(IV) complex with reduced dark toxicity. Under irradiation, RuOPt induces apoptosis, generates ROS, and inhibits tumor spheroid growth, demonstrating comparable phototoxicity.

For research use only. We do not sell to patients.

Formula: C₅₄H₅₆N₈O₁₃PtRu
Molecular Weight:1321.22

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

RuOPt Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

Molecular Weight 1321.22
Formula C₅₄H₅₆N₈O₁₃PtRu
SMILES

O=C1O[Pt]2(OC1=O)(OCCCOC(CCCC3=CC=[N]([Ru+2]456([N]7=CC=CC=C7C8=[N]6C=CC=C8)[N](C=CC=C9)=C9C%10=CC=CC=[N]%105)C(C%11=[N]4C=CC=C%11)=C3)=O)(OC(C%12=CC=CC=C%12)=O)[NH2][C@@H]%13CCCC[C@H]%13[NH2]2.O=C[O-].O=C[O-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lun Y, et al. A Highly Stable Photoactivatable Pt(IV) Prodrug with Lower Dark Cytotoxicity for Photochemotherapy. Inorg Chem. 2025 Sep 22;64(37):18950-18959. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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