NVOC cage-TMP-Halo
Based on 1 Customer Validation
NVOC cage-TMP-Halo is a cell-permeable and photoactivatable protein dimerization inducer. NVOC cage-TMP-Halo can rapidly and reversibly control protein localization in living cells. NVOC cage-TMP-Halo can be used for dynamic cellular processes research.
For research use only. We do not sell to patients.
- Purity: 96.03%
- CAS No.: 2137894-98-3
- Formula: C40H56ClN7O13
- Molecular Weight:878.36
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
NVOC cage-TMP-Halo (20μM, 60 min) exhibited dramatic recruitment of mCherry-eDHFR to centromeres with a t1/2 of ~ 15 s of expressing CENPB-GFP-Haloenzyme and mCherry-eDHFR HeLa cell line[1].
NVOC cage-TMP-Halo (20μM, 15, 30, and 60 min) has the power for spatially precise manipulation of protein localization in HeLa cell line[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2137894-98-3
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Appearance Solid
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Molecular Weight 878.36
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Formula C40H56ClN7O13
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Color Off-white to light yellow
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SMILES
COC1=C(OC)C=C(COC(NC2=NC(N)=C(CC3=CC(OC)=C(OCCCNC(CCC(NCCOCCOCCCCCCCl)=O)=O)C(OC)=C3)C=N2)=O)C([N+]([O-])=O)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 150 mg/mL (170.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1385 mL | 5.6924 mL | 11.3849 mL | 28.4621 mL |
| 5 mM | 0.2277 mL | 1.1385 mL | 2.2770 mL | 5.6924 mL | |
| 10 mM | 0.1138 mL | 0.5692 mL | 1.1385 mL | 2.8462 mL | |
| 15 mM | 0.0759 mL | 0.3795 mL | 0.7590 mL | 1.8975 mL | |
| 20 mM | 0.0569 mL | 0.2846 mL | 0.5692 mL | 1.4231 mL | |
| 25 mM | 0.0455 mL | 0.2277 mL | 0.4554 mL | 1.1385 mL | |
| 30 mM | 0.0379 mL | 0.1897 mL | 0.3795 mL | 0.9487 mL | |
| 40 mM | 0.0285 mL | 0.1423 mL | 0.2846 mL | 0.7116 mL | |
| 50 mM | 0.0228 mL | 0.1138 mL | 0.2277 mL | 0.5692 mL | |
| 60 mM | 0.0190 mL | 0.0949 mL | 0.1897 mL | 0.4744 mL | |
| 80 mM | 0.0142 mL | 0.0712 mL | 0.1423 mL | 0.3558 mL | |
| 100 mM | 0.0114 mL | 0.0569 mL | 0.1138 mL | 0.2846 mL |
NVOC cage-TMP-Halo Related Classifications
HY-153890 Related Classifications
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