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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
photophobia
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "photophobia" in MCE Product Catalog:
Cat. No.: HY-B1658A
CAS No.: 158930-17-7
Synonyms: (R)-Frovatriptan succinate hydrate; SB 209509 succinate hydrate; VML 251 succinate hydrate
Target:
Research Areas:
Frovatriptan succinate hydrate ((R)-Frovatriptan succinate hydrate) is a potent, high affinity, selective and orally active 5-HT1B (pK50 of 8.2) and 5-HT1D receptor agonist. Frovatriptan succinate hydrate exhibits >10-fold selectivity for 5-HT1B and 5-HT1D over 5-HT1A, 5-HT1F, and 5-HT7 and >1000-fold selectivity over other 5-HT, dopamine, histamine H1, and α1-adrenoceptor. Frovatriptan succinate hydrate has the potential for migraine research .
Target:
Research Areas:
AA41612 is a melanopsin (Opn4) inhibitor with an IC50 of 15.8 nM, a Ki of 0.43 nM, and a Kd of 0.28 nM. AA41612 competes with retinal for binding to melanopsin, blocks melanopsin activation, and inhibits melanopsin-mediated phototransduction processes without affecting rod- and cone-mediated responses. AA41612 attenuates light-induced melanopsin photocurrents, reduces light-induced cytoplasmic calcium elevation, and weakens high-irradiance pupillary light reflex in mice with induced classical photoreceptor degeneration. AA41612 can be used in studies related to migraine and photophobia .
Cat. No.: HY-B1658B
CAS No.: 158930-09-7
Synonyms: (R)-Frovatriptan succinate; SB 209509 succinate; VML 251 succinate
Target:
Research Areas:
Frovatriptan succinate ((R)-Frovatriptan succinate) is a potent, high affinity, selective and orally active 5-HT1B (pK50 of 8.2) and 5-HT1D receptor agonist. Frovatriptan succinate exhibits >10-fold selectivity for 5-HT1B and 5-HT1D over 5-HT1A, 5-HT1F, and 5-HT7 and >1000-fold selectivity over other 5-HT, dopamine, histamine H1, and α1-adrenoceptor. Frovatriptan succinate has the potential for migraine research .
Cat. No.: HY-B1658AR
CAS No.: 158930-17-7
Synonyms: (R)-Frovatriptan succinate hydrate (Standard); SB 209509 succinate hydrate (Standard); VML 251 succinate hydrate (Standard)
Target:
Research Areas:
Frovatriptan (succinate hydrate) (Standard) is the analytical standard of Frovatriptan (succinate hydrate). This product is intended for research and analytical applications. Frovatriptan succinate hydrate ((R)-Frovatriptan succinate hydrate) is a potent, high affinity, selective and orally active 5-HT1B (pK50 of 8.2) and 5-HT1D receptor agonist. Frovatriptan succinate hydrate exhibits >10-fold selectivity for 5-HT1B and 5-HT1D over 5-HT1A, 5-HT1F, and 5-HT7 and >1000-fold selectivity over other 5-HT, dopamine, histamine H1, and α1-adrenoceptor. Frovatriptan succinate hydrate has the potential for migraine research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
