12 Results for "

pterocarpan

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "pterocarpan" in MCE Product Catalog:

Trifolirhizin
Trifolirhizin
0 Images
Cat. No.: HY-N0616
CAS No.: 6807-83-6
Category:  

Flavonoids Leguminosae Plants Trifolium pratense Linn. Sophora flavescens Aiton Disease Research Fields Inflammation/Immunology Other Flavonoids Cancer

Target:  

Tyrosinase TNF Receptor Bacterial Apoptosis Autophagy AMPK mTOR ERK NF-κB

Trifolirhizin is a pterocarpan flavonoid found in the roots of Sophora flavescens. Trifolirhizin is a tyrosinase inhibitor with an IC50 value of 506.77 μM. Trifolirhizin reduces intracellular melanin production and modulates multiple signaling pathways including NFκB-MAPK, AMPK/mTOR, PI3K/Akt, MAPK-NFATc1 and EGFR-MAPK. Trifolirhizin targets biological molecules including PTK6 and COX-2, inhibits the activities of hyaluronidase, collagenase and elastase, induces apoptosis, autophagy and cell cycle arrest, and suppresses the proliferation, migration and invasion of cancer cells. Trifolirhizin exerts diverse pharmacological effects including anti-inflammatory, anti-asthmatic, bone-protective, renoprotective, antibacterial, antifungal, hepatoprotective, antiplatelet, estrogenic and wound-healing activities. Trifolirhizin can be used to investigate a broad range of malignant, inflammatory, metabolic and infectious disorders .
loading...
    loading...
View All Sizes
(-​)​-Maackiain
(-​)​-Maackiain
0 Images
Cat. No.: HY-N6051
CAS No.: 2035-15-6
Category:  

Infection Monophenols Leguminosae Terpenoids Phenols Diterpenoids Plants Sophora flavescens Aiton Disease Research Fields

Target:  

Fungal NOD-like Receptor (NLR) NF-κB

(-)-Maackiain is a pterocarpan phytoalexin produced from Sophora flavescens. (-)-Maackiain is toxic to several genera of fungal pathogens of legume and non legume hosts. (-)-Maackiain enhances the activation of NLRP3 inflammasome, inhibits the activation of NF-κB pathway, exhibiting thereby immunostimulatory and anti-inflammatory activities. (-)-Maackiain is orally active .
loading...
    loading...
View All Sizes
(S,S)-Pisatin
(S,S)-Pisatin
0 Images
Cat. No.: HY-N3045
CAS No.: 20186-22-5
Category:  

Natural Products Leguminosae Other Diseases Pisum sativum Linn Plants Disease Research Fields

Target:  

Drug Isomer

(S,S)-Pisatin is a dimeric pterocarpan derivative. (S,S)-Pisatin can inhibit plant growth .
loading...
    loading...
View All Sizes
(+)-Medicarpin
(+)-Medicarpin
0 Images
Cat. No.: HY-N6052
CAS No.: 33983-39-0
Synonyms: (+)-3-Hydroxy-9-methoxypterocarpan
Category:  

other families Monophenols Terpenoids Phenols Diterpenoids Plants Disease Research Fields Cancer

Target:  

Estrogen Receptor/ERR

(+)-Medicarpin, a pterocarpan, is a type of isoflavonoid isolated from several medicinal plant species with various biological effects, including Sophora japonica, Zollernia paraensis and Platymiscium yucatamun, Machaerium aristulatum, Platymiscium floribundum, and so on. (+)-Medicarpin potently inhibits osteoclastogenesis and promotes bone healing and increases bone mass by osteoblast differentiation with estrogen receptor (ER) β-mediated osteogenic action .
loading...
    loading...
View All Sizes
(-)-Maackiain (Standard)
(-)-Maackiain (Standard)
0 Images
Cat. No.: HY-N6051R
CAS No.: 2035-15-6
Category:  

Monophenols Leguminosae Terpenoids Phenols Diterpenoids Plants Sophora flavescens Aiton

Target:  

Reference Standards Fungal NOD-like Receptor (NLR) NF-κB

(-​)​-Maackiain (Standard) is the analytical standard of (-​)​-Maackiain. This product is intended for research and analytical applications. (-)-Maackiain is a pterocarpan phytoalexin produced from Sophora flavescens. (-)-Maackiain is toxic to several genera of fungal pathogens of legume and non legume hosts. (-)-Maackiain enhances the activation of NLRP3 inflammasome, inhibits the activation of NF-κB pathway, exhibiting thereby immunostimulatory and anti-inflammatory activities. (-)-Maackiain is orally active .
loading...
    loading...
View All Sizes
1,11b-Dihydro-11b-hydroxymedicarpin
1,11b-Dihydro-11b-hydroxymedicarpin
0 Images
Cat. No.: HY-N0976
CAS No.: 210537-04-5
Synonyms: 11b-Hydroxy-11b,1-dihydromedicarpin
Category:  

Natural Products Leguminosae Derris robusta Plants Disease Research Fields Inflammation/Immunology

Target:  

Interleukin Related Wnt

1,11b-Dihydro-11b-hydroxymedicarpin (11b-Hydroxy-11b,1-dihydromedicarpin) is a pterocarpan from Ononis viscosa subsp. breviflora is a Medicarpin derivative . Medicarpin, a natural pterocarpan, heals cortical bone defect by activation of Notch and Wnt canonical signaling pathways . Medicarpin prevents arthritis in post-menopausal conditions by arresting the expansion of TH17 cells and pro-inflammatory cytokines. Medicarpin down-regulates pro-inflammatory cytokines like TNF-α, IL-6 and IL-17A, while up-regulates anti-inflammatory cytokine IL-10 in arthritis (CIA) model of mice .
loading...
    loading...
View All Sizes
Trifolirhizin (Standard)
Trifolirhizin (Standard)
0 Images
Cat. No.: HY-N0616R
CAS No.: 6807-83-6
Category:  

Flavonoids Leguminosae Plants Trifolium pratense Linn. Sophora flavescens Aiton Other Flavonoids

Target:  

TNF Receptor Reference Standards Tyrosinase

Trifolirhizin (Standard) is the analytical standard of Trifolirhizin. This product is intended for research and analytical applications. Trifolirhizin is a pterocarpan flavonoid isolated from the roots of Sophora flavescens. Trifolirhizin possesses potent tyrosinase inhibitory activity with an IC50 of 506 μM . Trifolirhizin exhibits potential anti-inflammatory and anticancer activities .
loading...
    loading...
View All Sizes
(-)-Pterocarpin
(-)-Pterocarpin
0 Images
Cat. No.: HY-N17980
CAS No.: 524-97-0
Category:  

Natural Products Plants Millettia pulchra (Benth.) Kurz Fabaceae

Target:  

Drug Derivative

(-)-Pterocarpin is a pterocarpan found in Millettia pulchra .
loading...
    loading...
View All Sizes
Licoagroside D
Licoagroside D
0 Images
Cat. No.: HY-N7949
CAS No.: 464196-55-2
Category:  

Glycyrrhiza pallidiflora Maxim. Flavonoids Leguminosae Plants Other Flavonoids

Target:  

Others

Licoagroside D is a pterocarpan glycoside found in hairy root cultures of Glycyrrhiza pallidiflora .
loading...
    loading...
View All Sizes
Licoagrocarpin
Licoagrocarpin
0 Images
Cat. No.: HY-186188
CAS No.: 202815-29-0
Category:  

Glycyrrhiza glabra Linn. Flavonoids Leguminosae Plants Other Flavonoids

Target:  

Drug Intermediate

Licoagrocarpin is an isoprenylated pterocarpan, a type of naturally occurring flavonoid found in the roots of Glycyrrhiza glabra. Licoagrocarpin serves as a precursor in the biosynthetic pathway of Glabridin (HY-N0393) .
loading...
    loading...
View All Sizes
(6aR,11aR)-Edunol
(6aR,11aR)-Edunol
0 Images
Cat. No.: HY-N17604
CAS No.: 33909-74-9
Category:  

Flavonoids Plants Other Flavonoids Fabaceae

Target:  

Drug Derivative

(6aR,11aR)-Edunol (compound 10) is a pterocarpan and antiproliferative agent. (6aR,11aR)-Edunol can be found in the roots of Lonchocarpus bussei and the stem bark of Lonchocarpus eriocalyx. (6aR,11aR)-Edunol exerts antiproliferative effects against drug-sensitive leukemia cells and multidrug-resistant leukemia cells. (6aR,11aR)-Edunol can be used for the research of leukemia .
loading...
    loading...
View All Sizes
6'-Malonyltrifolirhizin
6'-Malonyltrifolirhizin
0 Images
Cat. No.: HY-N9548
CAS No.: 135574-57-1
Synonyms: Trifolirhizin 6''-O-malonate
Category:  

Flavonoids Leguminosae Plants Sophora flavescens Aiton Other Flavonoids

Target:  

Others

6'-Malonyltrifolirhizin (Trifolirhizin 6''-O-malonate) is a malonylated pterocarpan glucoside that can be isolated both from the roots and callus cultures of Sophora flavescens var. angustifolia .
loading...
    loading...
View All Sizes
  • 1
Assay Types