1 Result for "

rat kidney ALR1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "rat kidney ALR1" in MCE Product Catalog:

Cat. No.: HY-W151897
CAS No.: 309283-89-4
Synonyms: CMTI
Target:  

Aldose Reductase

Research Areas:  

Metabolic Disease

Cemtirestat (CMTI) is a carboxymethylated thiatriazinoindole inhibitor of aldose reductase (ALR2). Cemtirestat potently inhibits rat ocular lens ALR2 with an IC50 of 0.116 μM, and exhibits a 302-fold selectivity for rat kidney ALR1. Cemtirestat is applicable to the research of advanced diabetic complications .
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