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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
53 Results for "
ring-opened
" in MedChemExpress (MCE) Product Catalog:
Products (53)
53 Results for "ring-opened" in MCE Product Catalog:
2
Research Areas:
Bis(4-nitrophenyl) phosphate (BNPP) is an esterase inhibitor, inhibits the activity of esterases such as carboxylesterase. Bis(4-nitrophenyl) phosphate inhibits the degradation of Abiraterone in fresh plasma. Bis(4-nitrophenyl) phosphate can be used as a substrate to determine the enzymatic activity of phosphodiesterase in the roots of wetland plants. Bis(4-nitrophenyl) phosphate also acts as a catalyst for metallomicelles and a catalyst that promotes ring-opening polymerization (ROP) .
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1 Cited Publications
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ACP-5862 is a major active, circulating, pyrrolidine ring-opened metabolite of Acalabrutinib with an IC50 of 5.0 nM for Bruton tyrosine kinase (BTK). ACP‐5862 is a weak time‐dependent inactivator of CYP3A4 and CYP2C8. Acalabrutinib is an orally active, irreversible, and highly selective BTK inhibitor, with an IC50 of 3 nM and EC50 of 8 nM .
Cat. No.: HY-N0059
CAS No.: 10323-20-3
Synonyms: mPEG1000-Hydroxy; Polyethylene glycol monomethyl ether 1000
Synonyms: mPEG5000-Hydroxy; Polyethylene glycol monomethyl ether 5000
Research Areas:
m-PEG5000-OH (mPEG5000-Hydroxy) is a monomethoxypolyethylene glycol and also a macroinitiator for organocatalytic ring-opening polymerization of aliphatic cyclic carbonate monomers. m-PEG1000-OH can participate in the synthesis of amphiphilic block copolymers. Amphiphilic block copolymers can be used to prepare nanoscale micelles for active drug delivery .
Cat. No.: HY-N7082
CAS No.: 28697-53-2
Cat. No.: HY-W010610
CAS No.: 5239-82-7
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Research Areas:
2-Cyclopropylacetic acid is a substrate. 2-Cyclopropylacetic acid can produce a ring-opening product, which serves as an important precursor for the preparation of fused-ring molecules .
Cat. No.: HY-W133920
CAS No.: 25322-69-4
Synonyms: PPG 2000
Cat. No.: HY-19555A
CAS No.: 148554-65-8
Synonyms: Secorapamycin A monosodium
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Research Areas:
Seco Rapamycin sodium salt is the ring-opened product of Rapamycin. Seco-rapamycin is reported not to affect the mTOR function.
Cat. No.: HY-D0980
CAS No.: 138529-46-1
Synonyms: Biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin
Synonyms: Maleimide-PEG5000-Hydroxy
Cat. No.: HY-W011238
CAS No.: 6110-53-8
Synonyms: (Z)-1-Bromooctadec-9-ene
Target:
Research Areas:
Oleyl bromide ((Z)-1-Bromooctadec-9-ene) is a hydrophobic compound that can carry out ring-opening reaction through a process called "encapsulation". Oleyl bromine can also be used as the starting material in the synthesis of oleylphosphonates.
Cat. No.: HY-140696B
CAS No.: 9004-74-4
Synonyms: mPEG550-Hydroxy; Polyethylene glycol monomethyl ether 550
Cat. No.: HY-155902A
CAS No.: 88504-24-9
Synonyms: Maleimide-PEG2000-Hydroxy
Cat. No.: HY-140696H
CAS No.: 9004-74-4
Synonyms: mPEG750-Hydroxy; Polyethylene glycol monomethyl ether 750
Cat. No.: HY-19555
CAS No.: 147438-27-5
Synonyms: Secorapamycin A
Target:
Research Areas:
Seco Rapamycin (Secorapamycin A) is the ring-opened product of Rapamycin. Seco-rapamycin is reported not to affect the mTOR function .
Target:
Research Areas:
Epoxide hydrolase is an enzyme responsible for catalyzing the reaction between epoxides and water, converting epoxide groups into diols. Epoxide hydrolase plays a key role in the metabolism of environmental pollutants and lipids, contributing to detoxification, inflammation responses, and the regulation of cardiovascular system health. Additionally, epoxide hydrolase can be used in asymmetric catalytic reactions, such as the asymmetric ring-opening of epoxides, to produce chiral drug molecules .
Cat. No.: HY-W763546A
CAS No.: 26403-72-5
Cat. No.: HY-W095635
CAS No.: 17787-40-5
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
