![Glycine, N-[(1,1-dimethylethoxy)carbonyl]thio-L-phenylalanyl-, methyl ester](https://file.medchemexpress.com/product_pic/hy-78824.gif "Click to View Glycine, N-[(1,1-dimethylethoxy)carbonyl]thio-L-phenylalanyl-, methyl ester Product Detail")
![((1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-yl)methyl (N-(2-(2-(((N,N-bis(2-(((4-nitrophenoxy)carbonyl)oxy)ethyl)sulfamoyl)carbamoyl)oxy)ethoxy)ethyl)sulfamoyl)carbamate](https://file.medchemexpress.com/product_pic/hy-402912.gif "Click to View ((1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-yl)methyl (N-(2-(2-(((N,N-bis(2-(((4-nitrophenoxy)carbonyl)oxy)ethyl)sulfamoyl)carbamoyl)oxy)ethoxy)ethyl)sulfamoyl)carbamate Product Detail")
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
sulfamide
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "sulfamide" in MCE Product Catalog:
1
Cat. No.: HY-P4070
CAS No.: 1188379-43-2
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Cat. No.: HY-W033049
CAS No.: 119752-83-9
Synonyms: DABSO
Cat. No.: HY-12596
CAS No.: 871824-55-4
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JNJ-26489112, a CNS-active agent, exhibits broad-spectrum anticonvulsant activity in rodents against audiogenic, electrically-induced, and chemically-induced seizures. JNJ-26489112 inhibits voltage-gated Na + channels and N-type Ca 2+ channels, and is effective as a K + channel opener. JNJ-26489112 has very weak inhibition of CA-II (IC50=35 μM) and CA-I (18 μM) .
Cat. No.: HY-P11293
CAS No.: 1309855-53-5
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Cat. No.: HY-P4757
CAS No.: 108081-77-2
Cat. No.: HY-165393
CAS No.: 945009-57-4
Synonyms: N-(9E)-9-Octadecen-1-ylsulfamide
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Elaidyl-sulfamide (N-(9E)-9-Octadecen-1-ylsulfamide) is a PPARα agonist. Elaidyl-sulfamide reduces body weight gain and food intake and reduces circulating cholesterol levels and increases both glucose and insulin levels. Elaidyl-sulfamide has the potential for the research of complicated obesity .
Cat. No.: HY-P1321
CAS No.: 158859-98-4
Synonyms: 1229U91; GW1229
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Cat. No.: HY-124399
CAS No.: 925891-74-3
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Peroxisome proliferator-activated receptors (PPARs) play an important role in regulating lipid and glucose metabolism, and oleoylethanolamide (OEA) is a natural ligand for PPARα. N-Octadecyl-N'-propyl-sulfamide is an analog of OEA and a potent activator of PPARα, with selective binding affinity for PPARα (EC50=100 nM, compared to 120 nM for OEA). N-Octadecyl-N'-propyl-sulfamide (10 mg/kg; ip) inhibits food intake and reduces body weight gain in rats. At a dose of 1 mg/kg, N-Octadecyl-N'-propyl-sulfamide induces satiety, thereby reducing food intake, body weight, and plasma triglyceride concentrations in free-feeding Wistar rats and obese Zucker (fa/fa) rats.
Cat. No.: HY-78824
CAS No.: 128421-85-2
Cat. No.: HY-139574
CAS No.: 2243747-96-6
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Firzacorvir is a cyclic sulfamide compound and modulates HBV core protein. Firzacorvir has anti-HBV activity with EC50 < 1 μΜ .
Cat. No.: HY-126180
CAS No.: 1836185-18-2
BAY-866, a sulfamide campound, is an allosteric MEK1 inhibitor with an IC50 of 14 nM. BAY-866 inhibits cell growth of A375 (BRAF) and HCT116 (K-Ras) with IC50s of 13 nM and 277 nM, respectively. BAY-866 inhibits tumor growth in K-Ras-mutated A549 xenograft model .
Cat. No.: HY-P1321A
Synonyms: 1229U91 TFA; GW1229 TFA
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Cat. No.: HY-402912
CAS No.: 1898181-67-3
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((1R,8S,9s)-Bicyclonon-4-yn-9-yl) methyl (N-(2-(2-(((N,N-bis (2-(((4-nitrophenoxy) carbonyl) oxy) ethyl) sulfamoyl) carbamoyl) oxy) ethoxy) ethyl) sulfamoyl) carbamate is a bifunctional linker component containing a bicyclonon-4-yne click probe and a hydrophilic carbamoyl sulfamide group, which is used for the synthesis of antibody-drug conjugates .
Cat. No.: HY-79019
CAS No.: 14101-58-7
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N-Benzylsulfamide is a benzyl-substituted sulfamide reagent. N-Benzylsulfamide can be used as a synthetic precursor to generate dioxides of bicyclic thiadiazines .
Cat. No.: HY-187174
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CA IX-IN-6 is a selective human carbonic anhydrase IX (hCA IX) inhibitor, with Ki values of 8.9, 50.7, 551, and 64.4 nM against hCA IX, hCA XII, hCA I, and hCA II, respectively. CA IX-IN-6 binds to the active site via a classic sulfamide mode, coordinates with the catalytic Zn 2+ ion, forms a hydrogen bond with Thr200, and interacts with key active site residues. CA IX-IN-6 can be used in studies related to tumor-associated carbonic anhydrase inhibition .
Cat. No.: HY-P11480
CAS No.: 3105660-96-3
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Cat. No.: HY-187173
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CAXII-IN-4 is a human carbonic anhydrase XII (hCA XII) inhibitor with Ki values of 4.9, 3079, 62.5 and 58.4 nM against hCA XII, hCA I, hCA II and hCA IX, respectively, showing high selectivity toward tumor-associated hCA XII. CAXII-IN-4 binds to the active site of hCA XII via a classic sulfamide binding mode, coordinates with Zn 2+, forms a hydrogen bond with Ser133, and stabilizes the enzyme complex to reduce structural deviation. CAXII-IN-4 possesses both lipophilicity and polarity, and is predicted to have superior membrane permeability and oral absorbability. CAXII-IN-4 can be used in studies related to tumor-associated carbonic anhydrase inhibition .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
