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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
tryptophan synthase
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "tryptophan synthase" in MCE Product Catalog:
7
2
2 Cited Publications
1
Research Areas:
Glyphosate, a non-selective systemic biocide with broad-spectrum activity, is an herbicidal derivative of the amino acid glycine. Glyphosate inhibits the enzymatic activity of the 5-endopyruvylshikimate 3-phosphate synthase (EPSPS) in the shikimic acid pathway, preventing the synthesis of the aromatic amino acids tyrosine, phenylalanine, and tryptophan. Glyphosate induces oxidative stress, neuroinflammation, and mitochondrial dysfunction, processes that lead to neuronal death by autophagia, necrosis, or apoptosis, as well as the appearance of behavioral and motor disorders .
Cat. No.: HY-141466A
Purity: 97.85%
Research Areas:
Crotonyl-CoA tetrasodium, a high-energy acyl donor, is an intermediate in the fermentation of butyric acid, and in the metabolism of lysine and tryptophan. Crotonyl-CoA tetrasodium is important in the metabolism of fatty acids and amino acids. Crotonyl-CoA tetrasodium acts as a substrate for p300’s histone crotonyltransferase activity, competing with acetyl-CoA for p300-mediated histone acylation reactions. Crotonyl-CoA tetrasodium regulates global and gene-specific histone crotonylation levels in cells, with cellular concentration changes altering histone crotonylation at regulatory elements of activated genes. Crotonyl-CoA tetrasodium serves as the substrate for crotonyl-CoA reductase/carboxylase (CCRC)-catalyzed NADPH-mediated reduction and carbon dioxide trapping to form unusual alkylmalonyl-CoA polyketide synthase extender units. Crotonyl-CoA tetrasodium can be used for the research of LPS-induced inflammatory response .
Cat. No.: HY-W001542
CAS No.: 3416-18-0
Cat. No.: HY-100807S2
Cat. No.: HY-W747676
CAS No.: 287399-31-9
Cat. No.: HY-100807S1
CAS No.: 1346642-91-8
Cat. No.: HY-W001542R
CAS No.: 3416-18-0
Cat. No.: HY-166309
CAS No.: 116912-55-1
Research Areas:
Crotonyl-CoA tetralithium, a high-energy acyl donor, is an intermediate in the fermentation of butyric acid, and in the metabolism of lysine and tryptophan. Crotonyl-CoA tetralithium is important in the metabolism of fatty acids and amino acids. Crotonyl-CoA tetralithium acts as a substrate for p300’s histone crotonyltransferase activity, competing with acetyl-CoA for p300-mediated histone acylation reactions. Crotonyl-CoA tetralithium regulates global and gene-specific histone crotonylation levels in cells, with cellular concentration changes altering histone crotonylation at regulatory elements of activated genes. Crotonyl-CoA tetralithium serves as the substrate for crotonyl-CoA reductase/carboxylase (CCRC)-catalyzed NADPH-mediated reduction and carbon dioxide trapping to form unusual alkylmalonyl-CoA polyketide synthase extender units. Crotonyl-CoA tetralithium can be used for the research of LPS-induced inflammatory response .
Cat. No.: HY-122016A
CAS No.: 2119598-24-0
Target:
Research Areas:
BRD-4592 is an allosteric inhibitor targeting Mycobacterium tuberculosis tryptophan synthase (TrpAB). BRD-4592 binds at the α-β-subunit interface of TrpAB, with an IC50 of 70.9 nM for the α-subunit and 22.6 nM for the β-subunit .
Cat. No.: HY-W674285
CAS No.: 32999-55-6
Target:
Research Areas:
Oxindolylalanine, a tryptophan analogue, is an inhibitor of tryptophan indole-lyase (Ki: 5 μM) and tryptophan synthase. Tryptophan indole-lyase is a bacterial enzyme which catalyzes the reversible formation of indole and ammonium pyruvate from L-tryptophan.
Cat. No.: HY-B0863B
CAS No.: 38641-94-0
Target:
Research Areas:
Glyphosate isopropylammonium, a non-selective systemic biocide with broad-spectrum activity, is an herbicidal derivative of the amino acid glycine. Glyphosate isopropylammonium inhibits the enzymatic activity of the 5-endopyruvylshikimate 3-phosphate synthase (EPSPS) in the shikimic acid pathway, preventing the synthesis of the aromatic amino acids tyrosine, phenylalanine, and tryptophan. Glyphosate isopropylammonium induces oxidative stress, neuroinflammation, and mitochondrial dysfunction, processes that lead to neuronal death by autophagia, necrosis, or apoptosis, as well as the appearance of behavioral and motor disorders .
Cat. No.: HY-B0863S5
CAS No.: 2732154-65-1
Cat. No.: HY-Z8704
CAS No.: 184955-21-3
Target:
Research Areas:
Dioxyindolylalanine, a tryptophan analogue, is an inhibitor of tryptophan synthase.
Cat. No.: HY-E71817
Target:
Research Areas:
4-Dimethylallyltryptophan synthase (EC 2.5.1.34) is a transferase that can convert dimethylallyl diphosphate and L-tryptophan into 4-(3-methylbut-2-enyl)-L-tryptophan and diphosphate.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
