14 Results for "

uremic toxin

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "uremic toxin" in MCE Product Catalog:

6
6 Publications Verification
Cat. No.: HY-111431
CAS No.: 3233-58-7
Purity:  99.87%
Synonyms: p-Tolyl sulfate
p-Cresyl sulfate (p-Tolyl sulfate) is a uremic toxin, that can cause renal damage and dysfunction. p-Cresyl sulfate shows antiproliferation activity. p-Cresyl sulfate increases the protein expression of HIF-1α and VHL, decreases the protein expression of HIF-2α. p-Cresyl sulfate induces epithelial-mesenchymal transition (EMT). p-Cresyl sulfate activates the JNK and p38 MAPK signaling pathways .
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6
6 Publications Verification
Cat. No.: HY-111431A
CAS No.: 91978-69-7
Purity:  99.92%
Synonyms: p-Tolyl sulfate potassium
p-Cresyl sulfate potassium is a uremic toxin that binds to a prototype protein. p-Cresyl sulfate potassium activates the JNK and p38 MAPK signaling pathways. p-Cresyl sulfate potassium has pro-inflammatory activity .
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1 Cited Publications
Cat. No.: HY-W011910
CAS No.: 2642-37-7
Potassium 1H-indol-3-yl sulfate is a metabolite of tryptophan, produced by intestinal microorganisms and combined with sulfate in the liver before entering the circulatory system. Potassium 1H-indol-3-yl sulfate is a potent endogenous agonist of the aryl hydrocarbon receptor (AhR) and a urinary toxin. Potassium 1H-indol-3-yl sulfate can be used for research on kidney diseases .
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Cat. No.: HY-113432
CAS No.: 701-44-0
Purity:  99.94%
Synonyms: 2PY
Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibits poly(ADP-ribose) polymerase (PARP-1) activity in vitro .
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Cat. No.: HY-122009
CAS No.: 487-60-5
Purity:  99.88%
Synonyms: Indoxyl-β-D-glucoside
Indican (Indoxyl-β-D-glucoside), a glycoside of indoxyl, is a precursor of the dyesindigo and indirubin. Indican has a major metabolite, indoxyl sulfate (IS). IS, an uremic toxin, is a substrate/inhibitor of organic anion transporter (OAT) 1, OAT 3 and multidrug resistance-associated protein (MRP) 4 .
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Cat. No.: HY-111431AS
CAS No.: 2469278-96-2
Purity:  99.63%
Synonyms: p-Tolyl sulfate-d7 potassium
p-Cresol sulfate-d7 (potassium) is the deuterium labeled p-Cresyl sulfate potassium. p-Methylphenyl potassium sulfate is a prototype protein-bound uremic toxin[1][2].
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Cat. No.: HY-W416250
CAS No.: 17680-99-8
p-Cresol glucuronide, a metabolite of p-cresol, is a prototype protein-bound uremic toxin. p-Cresol glucuronide is associated with chronic kidney disease (CKD) .
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Cat. No.: HY-W674241A
4-Ethylphenyl sulfate sodium is an orally active and brain-penetrant gut microbial metabolite. 4-Ethylphenyl sulfate sodium downregulates Bcl2 expression, upregulates Bax expression, and induces cancer cell apoptosis via the endogenous apoptotic pathway. 4-Ethylphenyl sulfate sodium induces G2/M cell cycle arrest and reactive oxygen species (ROS) production. 4-Ethylphenyl sulfate sodium impairs oligodendrocyte maturation, reduces oligodendrocyte-neuron interactions, decreases axonal myelination levels, and shifts the oligodendrocyte population toward immature precursor cells. 4-Ethylphenyl sulfate sodium alters brain region-specific neural activity and functional connectivity in mice, and correlates with anxiety-like behaviors in mice .
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Cat. No.: HY-113432R
CAS No.: 701-44-0
Synonyms: 2PY (Standard)
Nudifloramide (Standard) is the analytical standard of Nudifloramide. This product is intended for research and analytical applications. Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibits poly(ADP-ribose) polymerase (PARP-1) activity in vitro .
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Cat. No.: HY-111431AR
CAS No.: 91978-69-7
Synonyms: p-Tolyl sulfate potassium (Standard)
p-Cresyl sulfate (potassium) (Standard) is the analytical standard of p-Cresyl sulfate (potassium). This product is intended for research and analytical applications. p-Cresyl sulfate (p-Tolyl sulfate) potassium is a uremic toxin, that can cause renal damage and dysfunction. p-Cresyl sulfate potassium shows antiproliferation activity. p-Cresyl sulfate potassium increases the protein expression of HIF-1α and VHL, decreases the protein expression of HIF-2α. p-Cresyl sulfate potassium induces epithelial-mesenchymal transition (EMT). p-Cresyl sulfate potassium activates the JNK and p38 MAPK signaling pathways .
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Cat. No.: HY-W019720
CAS No.: 22661-87-6
Target:  

Endogenous Metabolite

Research Areas:  

Inflammation/Immunology

1-Methylguanidine hydrochloride is a uremic toxin, which accumulate in dogs with renal failure and chronic kidney disese. 1-Methylguanidine hydrochloride enhances the oxidative metabolism and induces apoptosis in neutrophils .
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Cat. No.: HY-W654121
Synonyms: p-Tolyl sulfate-d4 potassium
p-Cresol sulfate-d4 (potassium) is deuterium labeled p-Cresyl sulfate (potassium). p-Cresyl sulfate potassium is a uremic toxin that binds to a prototype protein. p-Cresyl sulfate potassium activates the JNK and p38 MAPK signaling pathways. p-Cresyl sulfate potassium has pro-inflammatory activity .
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Cat. No.: HY-153993
CAS No.: 4918-96-1
Target:  

Bacterial

Research Areas:  

Endocrinology

Pyrocatechol sulfate is a dietary phenolic metabolite and uremic toxin. Pyrocatechol sulfate can be derived from diet and gut Bacterial metabolism. Plasma levels of Pyrocatechol sulfate are sensitive to alcohol exposure and withdrawal, and are negatively correlated with anxiety, depression, and craving for alcohol in severe alcohol use disorder. Pyrocatechol sulfate can be used in studies related to chronic kidney disease and severe alcohol use disorder .
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Cat. No.: HY-153993A
Target:  

Bacterial

Research Areas:  

Endocrinology

Pyrocatechol sulfate TEA is a dietary phenolic metabolite and uremic toxin. Pyrocatechol sulfate TEA can be derived from diet and gut Bacterial metabolism. Plasma levels of Pyrocatechol sulfate TEA are sensitive to alcohol exposure and withdrawal, and are negatively correlated with anxiety, depression, and craving for alcohol in severe alcohol use disorder. Pyrocatechol sulfate TEA can be used in studies related to chronic kidney disease and severe alcohol use disorder .
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