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  3. Pyrocatechol sulfate TEA

Pyrocatechol sulfate TEA is a dietary phenolic metabolite and uremic toxin. Pyrocatechol sulfate TEA can be derived from diet and gut Bacterial metabolism. Plasma levels of Pyrocatechol sulfate TEA are sensitive to alcohol exposure and withdrawal, and are negatively correlated with anxiety, depression, and craving for alcohol in severe alcohol use disorder. Pyrocatechol sulfate TEA can be used in studies related to chronic kidney disease and severe alcohol use disorder.

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Pyrocatechol sulfate TEA

Pyrocatechol sulfate TEA Chemical Structure

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Description

Pyrocatechol sulfate TEA is a dietary phenolic metabolite and uremic toxin. Pyrocatechol sulfate TEA can be derived from diet and gut Bacterial metabolism. Plasma levels of Pyrocatechol sulfate TEA are sensitive to alcohol exposure and withdrawal, and are negatively correlated with anxiety, depression, and craving for alcohol in severe alcohol use disorder. Pyrocatechol sulfate TEA can be used in studies related to chronic kidney disease and severe alcohol use disorder[1][2].

In Vivo

Pyrocatechol sulfate TEA accumulates in the plasma, liver, heart and kidney tissues of rats with chronic kidney disease, with a plasma-tissue level correlation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

291.36

Formula

C12H21NO5S

SMILES

CCN(CC)CC.O=S(O)(OC1=C(O)C=CC=C1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (343.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4322 mL 17.1609 mL 34.3218 mL
5 mM 0.6864 mL 3.4322 mL 6.8644 mL
View the Complete Stock Solution Preparation Table
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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.4322 mL 17.1609 mL 34.3218 mL 85.8045 mL
5 mM 0.6864 mL 3.4322 mL 6.8644 mL 17.1609 mL
10 mM 0.3432 mL 1.7161 mL 3.4322 mL 8.5805 mL
15 mM 0.2288 mL 1.1441 mL 2.2881 mL 5.7203 mL
20 mM 0.1716 mL 0.8580 mL 1.7161 mL 4.2902 mL
25 mM 0.1373 mL 0.6864 mL 1.3729 mL 3.4322 mL
30 mM 0.1144 mL 0.5720 mL 1.1441 mL 2.8602 mL
40 mM 0.0858 mL 0.4290 mL 0.8580 mL 2.1451 mL
50 mM 0.0686 mL 0.3432 mL 0.6864 mL 1.7161 mL
60 mM 0.0572 mL 0.2860 mL 0.5720 mL 1.4301 mL
80 mM 0.0429 mL 0.2145 mL 0.4290 mL 1.0726 mL
100 mM 0.0343 mL 0.1716 mL 0.3432 mL 0.8580 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Pyrocatechol sulfate TEA
Cat. No.:
HY-153993A
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