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urine output

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-128129
    UT-B-IN-1
    1 Publications Verification

    		 Urea Transporter Metabolic Disease
    UT-B-IN-1 (UTBINH-14) is a reversible, competitive and selective urea transporter-B (UT-B) inhibitor with IC50 values of 10 and 25 nM for human and mouse UT-B, respectively. UT-B-IN-1 shows low toxicity and high selectivity for UT-B over UT-A isoforms. UT-B-IN-1 increases urine output and reduces urine osmolality of mice. UT-B-IN-1 can be used for diuretic mechanism research .
    UT-B-IN-1
  • HY-W587755
    Benzylhydrochlorothiazide

    		Sodium Channel Cardiovascular Disease
    Benzylhydrochlorothiazide is an orally active thiazide diuretic. Benzylhydrochlorothiazide acts on the distal convoluted tubules of the kidneys, inhibiting the reabsorption of sodium chloride, thereby increasing urine output and reducing the body's fluid volume. Benzylhydrochlorothiazide has phototoxicity and a potential risk of skin reactions. Benzylhydrochlorothiazide can cause cell death when exposed to UVA radiation. Benzylhydrochlorothiazide is used in research on hypertension and edema .
    Benzylhydrochlorothiazide

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