5 Results for "

thyrotoxicosis

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "thyrotoxicosis" in MCE Product Catalog:

Cat. No.: HY-N10348
CAS No.: 585-95-5
Progoitrin is an orally active glucosinolate. As the precursor of goitrin (HY-N0224A), an antithyroid compound, progoitrin releases goitrin via hydrolysis by myrosinase or gastrointestinal glucosidase. Progoitrin converts to goitrin in vivo and exerts antithyroid activity by inhibiting the accumulation of radioactive iodine in the thyroid gland. Progoitrin can be used in the research of Graves' disease (thyrotoxicosis) .
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Cat. No.: HY-127024A
CAS No.: 1073179-55-1
Research Areas:  

Metabolic Disease

TR antagonist 2 (Compound 10a) is a competitive thyroid hormone receptors (TRα/β) antagonist (IC50=47 nM). TR antagonist 2 competes with triiodothyronine (T3) for binding to the ligand-binding domain of TR to block receptor-coactivator complex formation and inhibit target gene transcription, reducing thyroid hormone-mediated hypermetabolic effects. TR antagonist 2 is promising for research of hyperthyroidism (e.g., Graves' disease) and thyrotoxicosis .
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Cat. No.: HY-186138
CAS No.: 1073180-47-8
Research Areas:  

Metabolic Disease

TR modulator-1 (compound 10c) is a selective thyroid hormone receptor (TR) modulator. TR modulator-1 can be used in the research of hyperthyroidism and thyrotoxicosis .
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Cat. No.: HY-186138A
Research Areas:  

Metabolic Disease

TR modulator-1 (compound 10c) bromide is a selective thyroid hormone receptor (TR) modulator. TR modulator-1 bromide can be used in the research of hyperthyroidism and thyrotoxicosis .
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Cat. No.: HY-N10348A
CAS No.: 21087-77-4
Progoitrin potassium is an orally active glucosinolate. As the precursor of goitrin (HY-N0224A), an antithyroid compound, progoitrin releases goitrin via hydrolysis by myrosinase or gastrointestinal glucosidase. Progoitrin converts to goitrin in vivo and exerts antithyroid activity by inhibiting the accumulation of radioactive iodine in the thyroid gland. Progoitrin potassium can be used in the research of Graves' disease (thyrotoxicosis) .
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