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13-Deoxydaunorubicin hydroxylase

13-Deoxydaunorubicin hydroxylase (EC 1.14.13.181) shows broad substrate specificity for structures based on an anthracycline aglycone, but have a strong preference for 4-methoxy anthracycline intermediates (13-Deoxydaunorubicin and 13-dihydrodaunorubicin) over their 4-hydroxy analogues (13-deoxycarminomycin and 13-dihydrocarminomycin) , as well as a preference for substrates hydroxylated at the C-13 rather than the C-14 position.

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  • 13-Deoxydaunorubicin hydroxylase Chemical Structure
    13-Deoxydaunorubicin hydroxylase Chemical Structure
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  • 13-Deoxydaunorubicin hydroxylase